• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of annrheumdAnnals of the Rheumatic DiseasesCurrent TOCInstructions for authors
Ann Rheum Dis. Oct 2001; 60(10): 940–945.
PMCID: PMC1753380

Incidence and prevalence of juvenile arthritis in an urban population of southern Germany: a prospective study

Abstract

OBJECTIVE—To ascertain the incidence and prevalence of juvenile arthritis in a German urban population.
METHODS—All 766 paediatricians, orthopaedists, and rheumatologists working in practices or outpatient clinics in 12 south German towns were asked to report all patients who consulted them for juvenile arthritis during the year 1995. Patients with continuing symptoms were followed up for 9-12 months to obtain a final diagnosis. Extended measures of quality control were taken to control for known biases.
RESULTS—Of 457 reported cases, 294 were diagnosed with para-/postinfectious arthritis (PPA), 78 with juvenile chronic arthritis (JCA), and 18 with other forms of arthritis. Half of the PPA cases were classified as transient synovitis of the hip (SH). For JCA the reported annual incidence was 6.6 and the prevalence 14.8 per 100 000 subjects under 16 years of age. For PPA the reported incidence was 76 and the prevalence 4.4 per 100 000 subjects under 16. The incidence of rheumatic fever was clearly below 1 per 100 000 people under 16. A correction model was used to control for known biases and to adjust the estimates accordingly.
CONCLUSIONS—The results of this first prospective study on the incidence and prevalence of juvenile arthritis in Germany are consistent with a retrospective study performed in the Berlin area. Based on these results it was estimated that the annual frequency of juvenile arthritis in Germany is as follows: 750-900 incident JCA cases, 21 000 incident SH cases, and 21 000 incidence cases of other forms of PPA a year. The number of incidence cases of rheumatic fever is expected to be markedly lower than 150 a year. The total prevalence is expected to be 3600-4350 JCA cases, 2250-3000 SH cases, and the same number of other forms of PPA.

Full Text

The Full Text of this article is available as a PDF (172K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Truckenbrodt H. Zur Versorgungsstruktur rheumakranker Kinder und Jugendlicher in Westdeutschland. Z Rheumatol. 1990 Sep-Oct;49(5):260–267. [PubMed]
  • Gäre BA, Fasth A. Epidemiology of juvenile chronic arthritis in southwestern Sweden: a 5-year prospective population study. Pediatrics. 1992 Dec;90(6):950–958. [PubMed]
  • Kunnamo I, Kallio P, Pelkonen P. Incidence of arthritis in urban Finnish children. A prospective study. Arthritis Rheum. 1986 Oct;29(10):1232–1238. [PubMed]
  • Prieur AM, Le Gall E, Karman F, Edan C, Lasserre O, Goujard J. Epidemiologic survey of juvenile chronic arthritis in France. Comparison of data obtained from two different regions. Clin Exp Rheumatol. 1987 Jul-Sep;5(3):217–223. [PubMed]
  • Ozdogan H, Kasapçopur O, Dede H, Arisoy N, Beceren T, Yurdakul S, Yazici H. Juvenile chronic arthritis in a Turkish population. Clin Exp Rheumatol. 1991 Jul-Aug;9(4):431–435. [PubMed]
  • Kvien TK, Glennås A, Melby K, Granfors K, Andrup O, Karstensen B, Thoen JE. Reactive arthritis: incidence, triggering agents and clinical presentation. J Rheumatol. 1994 Jan;21(1):115–122. [PubMed]
  • Doubilet P, Begg CB, Weinstein MC, Braun P, McNeil BJ. Probabilistic sensitivity analysis using Monte Carlo simulation. A practical approach. Med Decis Making. 1985 Summer;5(2):157–177. [PubMed]
  • Southwood TR, Petty RE, Malleson PN, Delgado EA, Hunt DW, Wood B, Schroeder ML. Psoriatic arthritis in children. Arthritis Rheum. 1989 Aug;32(8):1007–1013. [PubMed]
  • Briggs RD, Baird KS, Gibson PH. Transient synovitis of the hip joint. J R Coll Surg Edinb. 1990 Feb;35(1):48–50. [PubMed]
  • Landin LA, Danielsson LG, Wattsgård C. Transient synovitis of the hip. Its incidence, epidemiology and relation to Perthes' disease. J Bone Joint Surg Br. 1987 Mar;69(2):238–242. [PubMed]
  • Graf J, Bernd L, Niethard FU, Kaps HP. Die Diagnostik bei der Coxitis fugax, der häufigsten Hüfterkrankung beim Kind. Klin Padiatr. 1991 Nov-Dec;203(6):448–451. [PubMed]
  • Vijlbrief AS, Bruijnzeels MA, van der Wouden JC, van Suijlekom-Smit LW. Incidence and management of transient synovitis of the hip: a study in Dutch general practice. Br J Gen Pract. 1992 Oct;42(363):426–428. [PMC free article] [PubMed]
  • Moe N, Rygg M. Epidemiology of juvenile chronic arthritis in northern Norway: a ten-year retrospective study. Clin Exp Rheumatol. 1998 Jan-Feb;16(1):99–101. [PubMed]
  • Kiessling U, Döring E, Listing J, Meincke J, Schöntube M, Strangfeld A, Zink A. Incidence and prevalence of juvenile chronic arthritis in East Berlin 1980-88. J Rheumatol. 1998 Sep;25(9):1837–1843. [PubMed]

Figures and Tables

Figure 1
Juvenile chronic arthritis (JCA) subgroups.
Figure 2
Distribution of age and sex in juvenile chronic arthritis.
Figure 3
Distribution of age and sex in incident synovitis of the hip.
Figure 4
Distribution of age and sex in incident para-/postinfectious arthritis.

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...