• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of annrheumdAnnals of the Rheumatic DiseasesCurrent TOCInstructions for authors
Ann Rheum Dis. Jul 1998; 57(7): 401–407.
PMCID: PMC1752666

Correlation between radiographically diagnosed osteophytes and magnetic resonance detected cartilage defects in the tibiofemoral joint

Abstract

OBJECTIVE—To assess the correlation between the presence of radiographically diagnosed osteophytes in the tibiofemoral joint (TFJ) and (1) magnetic resonance (MR) detected cartilage defects and meniscal lesions in the same joint and (2) knee pain.
METHODS—Fifty nine people, 29 men and 30 women, with chronic knee pain (aged 41-58 years, mean 50 years) were examined with posteroanterior weightbearing radiograms in semiflexion of both TFJ. The presence and grade of marginal and central osteophytes were assessed. On the same day, an MR examination was performed of the signal knee with proton density and T2 weighted turbo spin-echo sequences on a 1.0 T imager. Cartilage defects and meniscal abnormalities in the TFJ were noted. The subjects were questioned for current knee pain for each knee.
RESULTS—Marginal osteophytes had a sensitivity of 77%, specificity of 83%, and positive predictive value of 87% for MR detected cartilage defects in the TFJ and a sensitivity of 71%, specificity of 68%, and positive predictive value of 71% for meniscal abnormalities. A correlation (p<0.05) between osteophytes at the medial tibial condyle and knee pain was found.
CONCLUSIONS—With the presence of marginal osteophytes in the TFJ there is a high prevalence of MR detected cartilage defects in the same joint whether joint space narrowing (<3 mm) is present or not.

Keywords: knee; radiogram; osteoarthritis; osteophyte

Full Text

The Full Text of this article is available as a PDF (158K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • KELLGREN JH, LAWRENCE JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957 Dec;16(4):494–502. [PMC free article] [PubMed]
  • Spector TD, Hart DJ, Byrne J, Harris PA, Dacre JE, Doyle DV. Definition of osteoarthritis of the knee for epidemiological studies. Ann Rheum Dis. 1993 Nov;52(11):790–794. [PMC free article] [PubMed]
  • Cicuttini FM, Baker J, Hart DJ, Spector TD. Association of pain with radiological changes in different compartments and views of the knee joint. Osteoarthritis Cartilage. 1996 Jun;4(2):143–147. [PubMed]
  • Cicuttini FM, Baker J, Hart DJ, Spector TD. Choosing the best method for radiological assessment of patellofemoral osteoarthritis. Ann Rheum Dis. 1996 Feb;55(2):134–136. [PMC free article] [PubMed]
  • Hart DJ, Spector TD. The classification and assessment of osteoarthritis. Baillieres Clin Rheumatol. 1995 May;9(2):407–432. [PubMed]
  • Peterfy CG. MR imaging. Baillieres Clin Rheumatol. 1996 Nov;10(4):635–678. [PubMed]
  • Petersson IF, Boegård T, Saxne T, Silman AJ, Svensson B. Radiographic osteoarthritis of the knee classified by the Ahlbäck and Kellgren & Lawrence systems for the tibiofemoral joint in people aged 35-54 years with chronic knee pain. Ann Rheum Dis. 1997 Aug;56(8):493–496. [PMC free article] [PubMed]
  • Boegård T, Rudling O, Petersson IF, Sanfridsson J, Saxne T, Svensson B, Jonsson K. Postero-anterior radiogram of the knee in weight-bearing and semiflexion. Comparison with MR imaging. Acta Radiol. 1997 Nov;38(6):1063–1070. [PubMed]
  • Altman RD, Hochberg M, Murphy WA, Jr, Wolfe F, Lequesne M. Atlas of individual radiographic features in osteoarthritis. Osteoarthritis Cartilage. 1995 Sep;3 (Suppl A):3–70. [PubMed]
  • Buckland-Wright C. Protocols for precise radio-anatomical positioning of the tibiofemoral and patellofemoral compartments of the knee. Osteoarthritis Cartilage. 1995 Sep;3 (Suppl A):71–80. [PubMed]
  • Marshall JL. Periarticular osteophytes. Initiation and formation in the knee of the dog. Clin Orthop Relat Res. 1969 Jan-Feb;62:37–47. [PubMed]
  • Gilbertson EM. Development of periarticular osteophytes in experimentally induced osteoarthritis in the dog. A study using microradiographic, microangiographic, and fluorescent bone-labelling techniques. Ann Rheum Dis. 1975 Feb;34(1):12–25. [PMC free article] [PubMed]
  • Danielsson L, Hernborg J. Clinical and roentgenologic study of knee joints with osteophytes. Clin Orthop Relat Res. 1970 Mar-Apr;69:302–312. [PubMed]
  • Hernborg J, Nilsson BE. The relationship between osteophytes in the knee joint, osteoarthritis and aging. Acta Orthop Scand. 1973;44(1):69–74. [PubMed]
  • Tervonen O, Dietz MJ, Carmichael SW, Ehman RL. MR imaging of knee hyaline cartilage: evaluation of two- and three-dimensional sequences. J Magn Reson Imaging. 1993 Jul-Aug;3(4):663–668. [PubMed]
  • Broderick LS, Turner DA, Renfrew DL, Schnitzer TJ, Huff JP, Harris C. Severity of articular cartilage abnormality in patients with osteoarthritis: evaluation with fast spin-echo MR vs arthroscopy. AJR Am J Roentgenol. 1994 Jan;162(1):99–103. [PubMed]
  • Peterfy CG, van Dijke CF, Janzen DL, Glüer CC, Namba R, Majumdar S, Lang P, Genant HK. Quantification of articular cartilage in the knee with pulsed saturation transfer subtraction and fat-suppressed MR imaging: optimization and validation. Radiology. 1994 Aug;192(2):485–491. [PubMed]
  • Recht MP, Piraino DW, Paletta GA, Schils JP, Belhobek GH. Accuracy of fat-suppressed three-dimensional spoiled gradient-echo FLASH MR imaging in the detection of patellofemoral articular cartilage abnormalities. Radiology. 1996 Jan;198(1):209–212. [PubMed]
  • Disler DG. Fat-suppressed three-dimensional spoiled gradient-recalled MR imaging: assessment of articular and physeal hyaline cartilage. AJR Am J Roentgenol. 1997 Oct;169(4):1117–1123. [PubMed]
  • Fellner C, Geissler A, Held P, Strotzer M, Treibel W, Fellner F. Signal, contrast, and resolution in optimized PD- and T2-weighted turbo SE images of the knee. J Comput Assist Tomogr. 1995 Jan-Feb;19(1):96–105. [PubMed]
  • Escobedo EM, Hunter JC, Zink-Brody GC, Wilson AJ, Harrison SD, Fisher DJ. Usefulness of turbo spin-echo MR imaging in the evaluation of meniscal tears: comparison with a conventional spin-echo sequence. AJR Am J Roentgenol. 1996 Nov;167(5):1223–1227. [PubMed]
  • Cheung LP, Li KC, Hollett MD, Bergman AG, Herfkens RJ. Meniscal tears of the knee: accuracy of detection with fast spin-echo MR imaging and arthroscopic correlation in 293 patients. Radiology. 1997 May;203(2):508–512. [PubMed]
  • McDevitt C, Gilbertson E, Muir H. An experimental model of osteoarthritis; early morphological and biochemical changes. J Bone Joint Surg Br. 1977 Feb;59(1):24–35. [PubMed]
  • Alexander CJ. Osteoarthritis: a review of old myths and current concepts. Skeletal Radiol. 1990;19(5):327–333. [PubMed]
  • Buckland-Wright JC, Macfarlane DG, Jasani MK, Lynch JA. Quantitative microfocal radiographic assessment of osteoarthritis of the knee from weight bearing tunnel and semiflexed standing views. J Rheumatol. 1994 Sep;21(9):1734–1741. [PubMed]
  • Donnelly S, Hart DJ, Doyle DV, Spector TD. Spiking of the tibial tubercles--a radiological feature of osteoarthritis? Ann Rheum Dis. 1996 Feb;55(2):105–108. [PMC free article] [PubMed]
  • Reiff DB, Heron CW, Stoker DJ. Spiking of the tubercles of the intercondylar eminence of the tibial plateau in osteoarthritis. Br J Radiol. 1991 Oct;64(766):915–917. [PubMed]
  • Cooper C, Cushnaghan J, Kirwan JR, Dieppe PA, Rogers J, McAlindon T, McCrae F. Radiographic assessment of the knee joint in osteoarthritis. Ann Rheum Dis. 1992 Jan;51(1):80–82. [PMC free article] [PubMed]
  • Boegård T, Petersson IF, Jonsson K. Tibiofemoral joint space narrowing and meniscal lesions. Br J Rheumatol. 1997 Nov;36(11):1236–1236. [PubMed]

Figures and Tables

Figure 1
A 57 year old woman with a posteroanterior radiogram of the right knee demonstrating a marginal osteophyte grade 2 at the medial tibial condyle and an osteophyte grade 1 at the medial femoral condyle and at the lateral tibial ...
Figure 2
A 57 year old woman with (A) a posteroanterior radiogram of the right knee showing normal joint space width medially (4 mm) and laterally (5 mm). At the medial tibial condyle there is a marginal osteophyte grade 1 (arrow). ...
Figure 3
A 42 year old man with (A) a posteroanterior radiogram of the right knee, demonstrating normal joint space width medially (6 mm) and laterally (5 mm). (B) A close up of the lateral compartment to show a marginal osteophyte grade ...

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • Cited in Books
    Cited in Books
    PubMed Central articles cited in books
  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...