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Sex Transm Infect. Feb 2003; 79(1): e1.
PMCID: PMC1744588

Prevalence of and risk factors for hepatitis C virus infection among STD clinic clientele in Miami, Florida

Abstract

Objectives: Hepatitis C virus (HCV) is the most common chronic blood borne viral infection in the United States. We assessed the HCV prevalence, risk factors, and sensitivity of the Centers for Disease Control and Prevention's (CDC) routine screening criteria among clients of a large urban sexually transmitted disease (STD) clinic.

Methods: Participants were recruited from a public STD clinic in Miami, Florida, and were interviewed regarding known and potential risk factors. The survey assessed CDC screening criteria, as well as other risk factors (for example, intranasal drug use, history of incarceration, exchanging sex for money, number of lifetime sex partners, and history of an STD). Testing was done by enzyme immunoassay (EIA) and confirmed by recombinant immunoblot assay (RIBA).

Results: The prevalence of anti-HCV positivity was 4.7%. Four variables were significantly associated with being anti-HCV positive, independent of confounding factors. These included injection drug use (odds ratio (OR) = 31.6; 95% confidence intervals (CI) 11.0 to 90.5); history of incarceration (OR = 3.0; 95% CI 1.1 to 8.1); sexual contact with an HCV positive person (OR 12.7; 95% CI 2.5 to 64.7); and older age (OR 1.4; 95% CI 1.2, 1.6). The sensitivity of CDC's routine screening criteria was 69% and specificity was 91%.

Conclusions: The prevalence of anti-HCV in this clinic was similar to that determined in studies of comparable populations. Having sexual contact with an HCV positive person and history of incarceration were independently associated with being anti-HCV positive. CDC's screening criteria identified approximately two thirds of the anti-HCV positive participants.

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Selected References

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  • Fiscus SA, Kelly WF, Battigelli DA, Weber DJ, Schoenbach VJ, Landis SE, Wilber JC, Van der Horst CM. Hepatitis C virus seroprevalence in clients of sexually transmitted disease clinics in North Carolina. Sex Transm Dis. 1994 May-Jun;21(3):155–160. [PubMed]
  • Alter MJ, Hadler SC, Judson FN, Mares A, Alexander WJ, Hu PY, Miller JK, Moyer LA, Fields HA, Bradley DW, et al. Risk factors for acute non-A, non-B hepatitis in the United States and association with hepatitis C virus infection. JAMA. 1990 Nov 7;264(17):2231–2235. [PubMed]
  • Wejstål R. Sexual transmission of hepatitis C virus. J Hepatol. 1999;31 (Suppl 1):92–95. [PubMed]
  • Thomas DL, Zenilman JM, Alter HJ, Shih JW, Galai N, Carella AV, Quinn TC. Sexual transmission of hepatitis C virus among patients attending sexually transmitted diseases clinics in Baltimore--an analysis of 309 sex partnerships. J Infect Dis. 1995 Apr;171(4):768–775. [PubMed]
  • Nakashima K, Kashiwagi S, Hayashi J, Noguchi A, Hirata M, Kajiyama W, Urabe K, Minami K, Maeda Y. Sexual transmission of hepatitis C virus among female prostitutes and patients with sexually transmitted diseases in Fukuoka, Kyushu, Japan. Am J Epidemiol. 1992 Nov 1;136(9):1132–1137. [PubMed]
  • Thomas DL, Cannon RO, Shapiro CN, Hook EW, 3rd, Alter MJ, Quinn TC. Hepatitis C, hepatitis B, and human immunodeficiency virus infections among non-intravenous drug-using patients attending clinics for sexually transmitted diseases. J Infect Dis. 1994 May;169(5):990–995. [PubMed]
  • Akahane Y, Kojima M, Sugai Y, Sakamoto M, Miyazaki Y, Tanaka T, Tsuda F, Mishiro S, Okamoto H, Miyakawa Y, et al. Hepatitis C virus infection in spouses of patients with type C chronic liver disease. Ann Intern Med. 1994 May 1;120(9):748–752. [PubMed]
  • Serfaty L. Modes de transmission non transfusionnelle et non par toxicomanie intra-veineuse du VHC. Presse Med. 1999 Jun 12;28(21):1135–1140. [PubMed]
  • Hershow RC, Kalish LA, Sha B, Till M, Cohen M. Hepatitis C virus infection in Chicago women with or at risk for HIV infection: evidence for sexual transmission. Sex Transm Dis. 1998 Nov;25(10):527–532. [PubMed]
  • Conry-Cantilena C, VanRaden M, Gibble J, Melpolder J, Shakil AO, Viladomiu L, Cheung L, DiBisceglie A, Hoofnagle J, Shih JW, et al. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection. N Engl J Med. 1996 Jun 27;334(26):1691–1696. [PubMed]
  • Mele A, Corona R, Tosti ME, Palumbo F, Moiraghi A, Novaco F, Galanti C, Bernacchia R, Ferraro P. Beauty treatments and risk of parenterally transmitted hepatitis: results from the hepatitis surveillance system in Italy. Scand J Infect Dis. 1995;27(5):441–444. [PubMed]
  • Sun DX, Zhang FG, Geng YQ, Xi DS. Hepatitis C transmission by cosmetic tattooing in women. Lancet. 1996 Feb 24;347(9000):541–541. [PubMed]
  • Gunn RA, Murray PJ, Ackers ML, Hardison WG, Margolis HS. Screening for chronic hepatitis B and C virus infections in an urban sexually transmitted disease clinic: rationale for integrating services. Sex Transm Dis. 2001 Mar;28(3):166–170. [PubMed]
  • Weinstock HS, Bolan G, Reingold AL, Polish LB. Hepatitis C virus infection among patients attending a clinic for sexually transmitted diseases. JAMA. 1993 Jan 20;269(3):392–394. [PubMed]
  • Diaz T, Des Jarlais DC, Vlahov D, Perlis TE, Edwards V, Friedman SR, Rockwell R, Hoover D, Williams IT, Monterroso ER. Factors associated with prevalent hepatitis C: differences among young adult injection drug users in lower and upper Manhattan, New York City. Am J Public Health. 2001 Jan;91(1):23–30. [PMC free article] [PubMed]
  • Añn C, del Olmo JA, Llovet F, Serra MA, Gilabert S, Rodríguez F, Rodrigo JM. Virus C de la hepatitis entre la población penitenciaria de Valencia. Rev Esp Enferm Dig. 1995 Jul;87(7):505–508. [PubMed]
  • Haber PS, Parsons SJ, Harper SE, White PA, Rawlinson WD, Lloyd AR. Transmission of hepatitis C within Australian prisons. Med J Aust. 1999 Jul 5;171(1):31–33. [PubMed]
  • Butler TG, Dolan KA, Ferson MJ, McGuinness LM, Brown PR, Robertson PW. Hepatitis B and C in New South Wales prisons: prevalence and risk factors. Med J Aust. 1997 Feb 3;166(3):127–130. [PubMed]
  • Hedouin V, Gosset D. Infection par le virus de l'hépatite C en milieu carcéral. Etude prospective réalisée à Loos-lez-Lille. Gastroenterol Clin Biol. 1998 Jan;22(1):55–58. [PubMed]

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