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Clin Microbiol Rev. 1996 Apr; 9(2): 148–165.
PMCID: PMC172888

Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features.

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  • Abrutyn E, Goodhart GL, Roos K, Anderson R, Buxton A. Acinetobacter calcoaceticus outbreak associated with peritoneal dialysis. Am J Epidemiol. 1978 Apr;107(4):328–335. [PubMed]
  • Actis LA, Tolmasky ME, Crosa LM, Crosa JH. Effect of iron-limiting conditions on growth of clinical isolates of Acinetobacter baumannii. J Clin Microbiol. 1993 Oct;31(10):2812–2815. [PMC free article] [PubMed]
  • Alexander M, Ismail F, Jackman PJ, Noble WC. Fingerprinting Acinetobacter strains from clinical sources by numerical analysis of electrophoretic protein patterns. J Med Microbiol. 1984 Aug;18(1):55–64. [PubMed]
  • Alexander M, Rahman M, Taylor M, Noble WC. A study of the value of electrophoretic and other techniques for typing Acinetobacter calcoaceticus. J Hosp Infect. 1988 Nov;12(4):273–287. [PubMed]
  • Allardet-Servent A, Bouziges N, Carles-Nurit MJ, Bourg G, Gouby A, Ramuz M. Use of low-frequency-cleavage restriction endonucleases for DNA analysis in epidemiological investigations of nosocomial bacterial infections. J Clin Microbiol. 1989 Sep;27(9):2057–2061. [PMC free article] [PubMed]
  • Allen KD, Green HT. Hospital outbreak of multi-resistant Acinetobacter anitratus: an airborne mode of spread? J Hosp Infect. 1987 Mar;9(2):110–119. [PubMed]
  • Andrews HJ. Acinetobacter bacteriocin typing. J Hosp Infect. 1986 Mar;7(2):169–175. [PubMed]
  • Barre ME, Cook ML. Microbial factors in contact lens fitting. Am J Optom Physiol Opt. 1984 Jun;61(6):389–396. [PubMed]
  • Bauernfeind A. Classification of beta-lactamases. Rev Infect Dis. 1986 Nov-Dec;8 (Suppl 5):S470–S481. [PubMed]
  • Baumann P. Isolation of Acinetobacter from soil and water. J Bacteriol. 1968 Jul;96(1):39–42. [PMC free article] [PubMed]
  • Baumann P, Doudoroff M, Stanier RY. A study of the Moraxella group. II. Oxidative-negative species (genus Acinetobacter). J Bacteriol. 1968 May;95(5):1520–1541. [PMC free article] [PubMed]
  • Beck-Sagué CM, Jarvis WR, Brook JH, Culver DH, Potts A, Gay E, Shotts BW, Hill B, Anderson RL, Weinstein MP. Epidemic bacteremia due to Acinetobacter baumannii in five intensive care units. Am J Epidemiol. 1990 Oct;132(4):723–733. [PubMed]
  • Bergogne-Berezin E, Joly-Guillou ML. An underestimated nosocomial pathogen, Acinetobacter calcoaceticus. J Antimicrob Chemother. 1985 Nov;16(5):535–538. [PubMed]
  • Bergogne-Bérézin E, Joly-Guillou ML. Hospital infection with Acinetobacter spp.: an increasing problem. J Hosp Infect. 1991 Jun;18 (Suppl A):250–255. [PubMed]
  • Bergogne-Bérézin E, Joly-Guillou ML, Vieu JF. Epidemiology of nosocomial infections due to Acinetobacter calcoaceticus. J Hosp Infect. 1987 Sep;10(2):105–113. [PubMed]
  • Berk SL, McCabe WR. Meningitis caused by Acinetobacter calcoaceticus var anitratus. A specific hazard in neurosurgical patients. Arch Neurol. 1981 Feb;38(2):95–98. [PubMed]
  • Bernards AT, Dijkshoorn L, Van der Toorn J, Bochner BR, Van Boven CP. Phenotypic characterisation of Acinetobacter strains of 13 DNA-DNA hybridisation groups by means of the biolog system. J Med Microbiol. 1995 Feb;42(2):113–119. [PubMed]
  • Bouvet PJ, Grimont PA. Identification and biotyping of clinical isolates of Acinetobacter. Ann Inst Pasteur Microbiol. 1987 Sep-Oct;138(5):569–578. [PubMed]
  • Bouvet PJ, Jeanjean S. Delineation of new proteolytic genomic species in the genus Acinetobacter. Res Microbiol. 1989 May-Jun;140(4-5):291–299. [PubMed]
  • Bouvet PJ, Jeanjean S, Vieu JF, Dijkshoorn L. Species, biotype, and bacteriophage type determinations compared with cell envelope protein profiles for typing Acinetobacter strains. J Clin Microbiol. 1990 Feb;28(2):170–176. [PMC free article] [PubMed]
  • BRISOU J. Contribution a l'étude de la systématique des Pseudomonadaceae. Ann Inst Pasteur (Paris) 1957 Sep;93(3):397–404. [PubMed]
  • BRISOU J, PREVOT AR. Etudes de systématique bactérienne. X. Révision des especes réunies dans le genre Achromobacter. Ann Inst Pasteur (Paris) 1954 Jun;86(6):722–728. [PubMed]
  • Buisson Y, Tran Van Nhieu G, Ginot L, Bouvet P, Schill H, Driot L, Meyran M. Nosocomial outbreaks due to amikacin-resistant tobramycin-sensitive Acinetobacter species: correlation with amikacin usage. J Hosp Infect. 1990 Jan;15(1):83–93. [PubMed]
  • Buxton AE, Anderson RL, Werdegar D, Atlas E. Nosocomial respiratory tract infection and colonization with Acinetobacter calcoaceticus. Epidemiologic characteristics. Am J Med. 1978 Sep;65(3):507–513. [PubMed]
  • Castle M, Tenney JH, Weinstein MP, Eickhoff TC. Outbreak of a multiply resistant Acinetobacter in a surgical intensive care unit: epidemiology and control. Heart Lung. 1978 Jul-Aug;7(4):641–644. [PubMed]
  • Cefai C, Richards J, Gould FK, McPeake P. An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment. J Hosp Infect. 1990 Feb;15(2):177–182. [PubMed]
  • Chirnside ED, Emmerson AM, Smith JT. A follow-up survey of transferable, plasmid-encoded trimethoprim resistance in a general hospital (1975-1983). J Antimicrob Chemother. 1985 Oct;16(4):419–434. [PubMed]
  • Chopade BA, Wise PJ, Towner KJ. Plasmid transfer and behaviour in Acinetobacter calcoaceticus EBF65/65. J Gen Microbiol. 1985 Oct;131(10):2805–2811. [PubMed]
  • Christensen EA, Gerner-Smidt P, Kristensen H. Radiation resistance of clinical Acinetobacter spp.: a need for concern? J Hosp Infect. 1991 Jun;18(2):85–92. [PubMed]
  • Collis CM, Grammaticopoulos G, Briton J, Stokes HW, Hall RM. Site-specific insertion of gene cassettes into integrons. Mol Microbiol. 1993 Jul;9(1):41–52. [PubMed]
  • Craven DE, Barber TW, Steger KA, Montecalvo MA. Nosocomial pneumonia in the 1990s: update of epidemiology and risk factors. Semin Respir Infect. 1990 Sep;5(3):157–172. [PubMed]
  • Crombach WH, Dijkshoorn L, van Noort-Klaassen M, Niessen J, van Knippenberg-Gordebeke G. Control of an epidemic spread of a multi-resistant strain of Acinetobacter calcoaceticus in a hospital. Intensive Care Med. 1989;15(3):166–170. [PubMed]
  • Cunha BA, Klimek JJ, Gracewski J, McLaughlin JC, Quintiliani R. A common source outbreak of Acinetobacter pulmonary infections traced to Wright respirometers. Postgrad Med J. 1980 Mar;56(653):169–172. [PMC free article] [PubMed]
  • Das BC, Ayliffe G. Serotyping of Acinetobacter calcoaceticus. J Clin Pathol. 1984 Dec;37(12):1388–1391. [PMC free article] [PubMed]
  • Devaud M, Kayser FH, Bächi B. Transposon-mediated multiple antibiotic resistance in Acinetobacter strains. Antimicrob Agents Chemother. 1982 Aug;22(2):323–329. [PMC free article] [PubMed]
  • Dietz JW, Jr, Goodrich JA, Brown WB. Acinetobacter calcoaceticus foot infection secondary to high-pressure injection injury: a case report. Foot Ankle. 1988 Feb;8(4):216–222. [PubMed]
  • Dijkshoorn L, Aucken HM, Gerner-Smidt P, Kaufmann ME, Ursing J, Pitt TL. Correlation of typing methods for Acinetobacter isolates from hospital outbreaks. J Clin Microbiol. 1993 Mar;31(3):702–705. [PMC free article] [PubMed]
  • Dijkshoorn L, Michel MF, Degener JE. Cell envelope protein profiles of Acinetobacter calcoaceticus strains isolated in hospitals. J Med Microbiol. 1987 Jun;23(4):313–319. [PubMed]
  • Dijkshoorn L, van Dalen R, van Ooyen A, Bijl D, Tjernberg I, Michel MF, Horrevorts AM. Endemic acinetobacter in intensive care units: epidemiology and clinical impact. J Clin Pathol. 1993 Jun;46(6):533–536. [PMC free article] [PubMed]
  • Dijkshoorn L, Van Ooyen A, Hop WC, Theuns M, Michel MF. Comparison of clinical Acinetobacter strains using a carbon source growth assay. Epidemiol Infect. 1990 Jun;104(3):443–453. [PMC free article] [PubMed]
  • Dijkshoorn L, Van Vianen W, Degener JE, Michel MF. Typing of Acinetobacter calcoaceticus strains isolated from hospital patients by cell envelope protein profiles. Epidemiol Infect. 1987 Dec;99(3):659–667. [PMC free article] [PubMed]
  • Dowding JE. A novel aminoglycoside-modifying enzyme from a clinical isolate of Acinetobacter. J Gen Microbiol. 1979 Jan;110(1):239–241. [PubMed]
  • Echenique JR, Arienti H, Tolmasky ME, Read RR, Staneloni RJ, Crosa JH, Actis LA. Characterization of a high-affinity iron transport system in Acinetobacter baumannii. J Bacteriol. 1992 Dec;174(23):7670–7679. [PMC free article] [PubMed]
  • Elisha BG, Steyn LM. Aminoglycoside-O-phosphotransferase (APH (3'')) activity in a clinical isolate of Acinetobacter calcoaceticus. S Afr Med J. 1989 Mar 4;75(5):220–222. [PubMed]
  • Fagon JY, Chastre J, Domart Y, Trouillet JL, Pierre J, Darne C, Gibert C. Nosocomial pneumonia in patients receiving continuous mechanical ventilation. Prospective analysis of 52 episodes with use of a protected specimen brush and quantitative culture techniques. Am Rev Respir Dis. 1989 Apr;139(4):877–884. [PubMed]
  • Fagon JY, Chastre J, Hance AJ, Montravers P, Novara A, Gibert C. Nosocomial pneumonia in ventilated patients: a cohort study evaluating attributable mortality and hospital stay. Am J Med. 1993 Mar;94(3):281–288. [PubMed]
  • French GL, Casewell MW, Roncoroni AJ, Knight S, Phillips I. A hospital outbreak of antibiotic-resistant Acinetobacter anitratus: epidemiology and control. J Hosp Infect. 1980 Jun;1(2):125–131. [PubMed]
  • Galvao C, Swartz R, Rocher L, Reynolds J, Starmann B, Wilson D. Acinetobacter peritonitis during chronic peritoneal dialysis. Am J Kidney Dis. 1989 Aug;14(2):101–104. [PubMed]
  • Garcia I, Fainstein V, LeBlanc B, Bodey GP. In vitro activities of new beta-lactam antibiotics against Acinetobacter spp. Antimicrob Agents Chemother. 1983 Aug;24(2):297–299. [PMC free article] [PubMed]
  • Seifert H, Baginski R, Schulze A, Pulverer G. The distribution of Acinetobacter species in clinical culture materials. Zentralbl Bakteriol. 1993 Nov;279(4):544–552. [PubMed]
  • Gerner-Smidt P. Endemic occurrence of Acinetobacter calcoaceticus biovar anitratus in an intensive care unit. J Hosp Infect. 1987 Nov;10(3):265–272. [PubMed]
  • Gerner-Smidt P. Frequency of plasmids in strains of Acinetobacter calcoaceticus. J Hosp Infect. 1989 Jul;14(1):23–28. [PubMed]
  • Gerner-Smidt P. Ribotyping of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex. J Clin Microbiol. 1992 Oct;30(10):2680–2685. [PMC free article] [PubMed]
  • Gerner-Smidt P. Acinetobacter: epidemiological and taxonomic aspects. APMIS Suppl. 1994;47:1–41. [PubMed]
  • Gerner-Smidt P, Frederiksen W. Acinetobacter in Denmark: I. Taxonomy, antibiotic susceptibility, and pathogenicity of 112 clinical strains. APMIS. 1993 Nov;101(11):815–825. [PubMed]
  • Gerner-Smidt P, Tjernberg I. Acinetobacter in Denmark: II. Molecular studies of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex. APMIS. 1993 Nov;101(11):826–832. [PubMed]
  • Gerner-Smidt P, Tjernberg I, Ursing J. Reliability of phenotypic tests for identification of Acinetobacter species. J Clin Microbiol. 1991 Feb;29(2):277–282. [PMC free article] [PubMed]
  • Getchell-White SI, Donowitz LG, Gröschel DH. The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calcoaceticus. Infect Control Hosp Epidemiol. 1989 Sep;10(9):402–407. [PubMed]
  • Giammanco A, Vieu JF, Bouvet PJ, Sarzana A, Sinatra A. A comparative assay of epidemiological markers for Acinetobacter strains isolated in a hospital. Zentralbl Bakteriol. 1989 Dec;272(2):231–241. [PubMed]
  • Glew RH, Moellering RC, Jr, Kunz LJ. Infections with Acinetobacter calcoaceticus (Herellea vaginicola): clinical and laboratory studies. Medicine (Baltimore) 1977 Mar;56(2):79–97. [PubMed]
  • Go ES, Urban C, Burns J, Kreiswirth B, Eisner W, Mariano N, Mosinka-Snipas K, Rahal JJ. Clinical and molecular epidemiology of acinetobacter infections sensitive only to polymyxin B and sulbactam. Lancet. 1994 Nov 12;344(8933):1329–1332. [PubMed]
  • Goldstein FW, Labigne-Roussel A, Gerbaud G, Carlier C, Collatz E, Courvalin P. Transferable plasmid-mediated antibiotic resistance in Acinetobacter. Plasmid. 1983 Sep;10(2):138–147. [PubMed]
  • Gouby A, Carles-Nurit MJ, Bouziges N, Bourg G, Mesnard R, Bouvet PJ. Use of pulsed-field gel electrophoresis for investigation of hospital outbreaks of Acinetobacter baumannii. J Clin Microbiol. 1992 Jun;30(6):1588–1591. [PMC free article] [PubMed]
  • GRABER CD, RABIN ER, MASON AD, Jr, VOGEL EH., Jr Increasing incidence of nosocomial Herellea vaginicola infections in burned patients. Surg Gynecol Obstet. 1962 Jan;114:109–112. [PubMed]
  • Gradon JD, Chapnick EK, Lutwick LI. Infective endocarditis of a native valve due to Acinetobacter: case report and review. Clin Infect Dis. 1992 May;14(5):1145–1148. [PubMed]
  • Gräser Y, Klare I, Halle E, Gantenberg R, Buchholz P, Jacobi HD, Presber W, Schönian G. Epidemiological study of an Acinetobacter baumannii outbreak by using polymerase chain reaction fingerprinting. J Clin Microbiol. 1993 Sep;31(9):2417–2420. [PMC free article] [PubMed]
  • Green AR, Milling MA. Infection with Acinetobacter in a burns unit. Burns Incl Therm Inj. 1983 Mar;9(4):292–294. [PubMed]
  • Grehn M, von Graevenitz A. Search for Acinetobacter calcoaceticus subsp. anitratus: enrichment of fecal samples. J Clin Microbiol. 1978 Sep;8(3):342–343. [PMC free article] [PubMed]
  • Hartstein AI, Rashad AL, Liebler JM, Actis LA, Freeman J, Rourke JW, Jr, Stibolt TB, Tolmasky ME, Ellis GR, Crosa JH. Multiple intensive care unit outbreak of Acinetobacter calcoaceticus subspecies anitratus respiratory infection and colonization associated with contaminated, reusable ventilator circuits and resuscitation bags. Am J Med. 1988 Nov;85(5):624–631. [PubMed]
  • Henriksen SD. Moraxella, Acinetobacter, and the Mimeae. Bacteriol Rev. 1973 Dec;37(4):522–561. [PMC free article] [PubMed]
  • Herman NJ, Juni E. Isolation and characterization of a generalized transducing bacteriophage for Acinetobacter. J Virol. 1974 Jan;13(1):46–52. [PMC free article] [PubMed]
  • Hikida M, Yoshida M, Mitsuhashi S, Inoue M. Purification and properties of a cephalosporinase from Acinetobacter calcoaceticus. J Antibiot (Tokyo) 1989 Jan;42(1):123–126. [PubMed]
  • Hoffmann S, Mabeck CE, Vejlsgaard R. Bacteriuria caused by Acinetobacter calcoaceticus biovars in a normal population and in general practice. J Clin Microbiol. 1982 Sep;16(3):443–451. [PMC free article] [PubMed]
  • Holton J. A note on the preparation and use of a selective differential medium for the isolation of Acinetobacter spp. from clinical sources. J Appl Bacteriol. 1983 Feb;54(1):141–142. [PubMed]
  • Horrevorts A, Bergman K, Kollée L, Breuker I, Tjernberg I, Dijkshoorn L. Clinical and epidemiological investigations of Acinetobacter genomospecies 3 in a neonatal intensive care unit. J Clin Microbiol. 1995 Jun;33(6):1567–1572. [PMC free article] [PubMed]
  • Jawad A, Hawkey PM, Heritage J, Snelling AM. Description of Leeds Acinetobacter Medium, a new selective and differential medium for isolation of clinically important Acinetobacter spp., and comparison with Herellea agar and Holton's agar. J Clin Microbiol. 1994 Oct;32(10):2353–2358. [PMC free article] [PubMed]
  • Johnson DR, Love-Dixon MA, Brown WJ, Levine DP, Downes FP, Hall WN. Delayed detection of an increase in resistant Acinetobacter at a Detroit hospital. Infect Control Hosp Epidemiol. 1992 Jul;13(7):394–398. [PubMed]
  • Johnson JL, Anderson RS, Ordal EJ. Nucleic acid homologies among oxidase-negative Moraxella species. J Bacteriol. 1970 Feb;101(2):568–573. [PMC free article] [PubMed]
  • Joly-Guillou ML, Bergogne-Berezin E. Evolution d'Acinetobacter calcoaceticus en milieu hospitalier, de 1971 à 1984. Presse Med. 1985 Dec 28;14(46):2331–2335. [PubMed]
  • Joly-Guillou ML, Bergogne-Berezin E, Vieu JF. Epidémiologie et résistance aux antibiotiques des Acinetobacter en milieu hospitalier. Bilan de 5 années. Presse Med. 1990 Mar 3;19(8):357–361. [PubMed]
  • Joly-Guillou ML, Bergogne-Berezin E. Présence d'une beta-lactamase à spectre élargi chez Acinetobacter baumanii. Presse Med. 1990 Apr 7;19(14):672–673. [PubMed]
  • Joly-Guillou ML, Bergogne-Bérézin E. In-vitro activity of sparfloxacin, pefloxacin, ciprofloxacin and temafloxacin against clinical isolates of Acinetobacter spp. J Antimicrob Chemother. 1992 Apr;29(4):466–468. [PubMed]
  • Joly-Guillou ML, Bergogne-Bérézin E, Moreau N. Enzymatic resistance to beta-lactams and aminoglycosides in Acinetobacter calcoaceticus. J Antimicrob Chemother. 1987 Dec;20(6):773–776. [PubMed]
  • Joly-Guillo ML, Vallée E, Bergogne-Bérézin E, Philippon A. Distribution of beta-lactamases and phenotype analysis in clinical strains of Acinetobacter calcoaceticus. J Antimicrob Chemother. 1988 Nov;22(5):597–604. [PubMed]
  • Joly-Guillou ML, Bergogne-Berezin E, Vieu JF. A study of the relationships between antibiotic resistance phenotypes, phage-typing and biotyping of 117 clinical isolates of Acinetobacter spp. J Hosp Infect. 1990 Jul;16(1):49–58. [PubMed]
  • Juni E. Interspecies transformation of Acinetobacter: genetic evidence for a ubiquitous genus. J Bacteriol. 1972 Nov;112(2):917–931. [PMC free article] [PubMed]
  • Juni E. Genetics and physiology of Acinetobacter. Annu Rev Microbiol. 1978;32:349–371. [PubMed]
  • Juni E, Janik A. Transformation of Acinetobacter calco-aceticus (Bacterium anitratum). J Bacteriol. 1969 Apr;98(1):281–288. [PMC free article] [PubMed]
  • Kämpfer P, Tjernberg I, Ursing J. Numerical classification and identification of Acinetobacter genomic species. J Appl Bacteriol. 1993 Sep;75(3):259–268. [PubMed]
  • Kaplan N, Rosenberg E, Jann B, Jann K. Structural studies of the capsular polysaccharide of Acinetobacter calcoaceticus BD4. Eur J Biochem. 1985 Oct 15;152(2):453–458. [PubMed]
  • Kelkar R, Gordon SM, Giri N, Rao K, Ramakrishnan G, Saikia T, Nair CN, Kurkure PA, Pai SK, Jarvis WR, et al. Epidemic iatrogenic Acinetobacter spp. meningitis following administration of intrathecal methotrexate. J Hosp Infect. 1989 Oct;14(3):233–243. [PubMed]
  • Kitzis MD, Goldstein FW, Labia R, Acar JF. Activité du sulbactam et de l'acide clavulanique, seuls et associés, sur Acinetobacter calcoaceticus. Ann Microbiol (Paris) 1983 Mar-Apr;134A(2):163–168. [PubMed]
  • Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985 Oct;13(10):818–829. [PubMed]
  • Kropec A, Hübner J, Daschner FD. Comparison of three typing methods in hospital outbreaks of Acinetobacter calcoaceticus infection. J Hosp Infect. 1993 Feb;23(2):133–141. [PubMed]
  • Lambert T, Gerbaud G, Bouvet P, Vieu JF, Courvalin P. Dissemination of amikacin resistance gene aphA6 in Acinetobacter spp. Antimicrob Agents Chemother. 1990 Jun;34(6):1244–1248. [PMC free article] [PubMed]
  • Lambert T, Gerbaud G, Courvalin P. Transferable amikacin resistance in Acinetobacter spp. due to a new type of 3'-aminoglycoside phosphotransferase. Antimicrob Agents Chemother. 1988 Jan;32(1):15–19. [PMC free article] [PubMed]
  • Lambert T, Gerbaud G, Galimand M, Courvalin P. Characterization of Acinetobacter haemolyticus aac(6')-Ig gene encoding an aminoglycoside 6'-N-acetyltransferase which modifies amikacin. Antimicrob Agents Chemother. 1993 Oct;37(10):2093–2100. [PMC free article] [PubMed]
  • Larson E. A decade of nosocomial Acinetobacter. Am J Infect Control. 1984 Feb;12(1):14–18. [PubMed]
  • Leonov Y, Schlaeffer F, Karpuch J, Bourvin A, Shemesh Y, Lewinson G. Ciprofloxacin in the treatment of nosocomial multiply resistant Acinetobacter calcoaceticus bacteremia. Infection. 1990 Jul-Aug;18(4):234–236. [PubMed]
  • Lortholary O, Fagon JY, Hoi AB, Slama MA, Pierre J, Giral P, Rosenzweig R, Gutmann L, Safar M, Acar J. Nosocomial acquisition of multiresistant Acinetobacter baumannii: risk factors and prognosis. Clin Infect Dis. 1995 Apr;20(4):790–796. [PubMed]
  • Lye WC, Lee EJ, Ang KK. Acinetobacter peritonitis in patients on CAPD: characteristics and outcome. Adv Perit Dial. 1991;7:176–179. [PubMed]
  • Mark DB, Gaynon MW. Trauma-induced endophthalmitis caused by Acinetobacter anitratus. Br J Ophthalmol. 1983 Feb;67(2):124–126. [PMC free article] [PubMed]
  • Martin P, Jullien E, Courvalin P. Nucleotide sequence of Acinetobacter baumannii aphA-6 gene: evolutionary and functional implications of sequence homologies with nucleotide-binding proteins, kinases and other aminoglycoside-modifying enzymes. Mol Microbiol. 1988 Sep;2(5):615–625. [PubMed]
  • Martin RW, Martin DL, Levy CS. Acinetobacter osteomyelitis from a hamster bite. Pediatr Infect Dis J. 1988 May;7(5):364–365. [PubMed]
  • Melki TS, Sramek SJ. Trauma-induced Acinetobacter lwoffi endophthalmitis. Am J Ophthalmol. 1992 May 15;113(5):598–599. [PubMed]
  • Morohoshi T, Saito T. beta-Lactamase and beta-lactam antibiotics resistance in acinetobacter anitratum (syn: A. calcoaceticus). J Antibiot (Tokyo) 1977 Nov;30(11):969–973. [PubMed]
  • Mortensen JE, LaRocco MT, Steiner B, Ribner B. Protein fingerprinting for the determination of relatedness in Acinetobacter calcoaceticus subspecies anitratus isolated from patients in a surgical intensive care unit. Infect Control. 1987 Dec;8(12):512–515. [PubMed]
  • Muller-Serieys C, Lesquoy JB, Perez E, Fichelle A, Boujeois B, Joly-Guillou ML, Bergogne-Berezin E. Infections nosocomiales à acinetobacter. Epidémiologie et difficultés thérapeutiques. Presse Med. 1989 Jan 28;18(3):107–110. [PubMed]
  • Murray BE, Moellering RC., Jr Aminoglycoside-modifying enzymes among clinical isolates of Acinetobacter calcoaceticus subsp. anitratus (Herellea vaginicola): explanation for high-level aminoglycoside resistance. Antimicrob Agents Chemother. 1979 Feb;15(2):190–199. [PMC free article] [PubMed]
  • Murray BE, Moellering RC., Jr Evidence of plasmid-mediated production of aminoglycoside-modifying enzymes not previously described in Acinetobacter. Antimicrob Agents Chemother. 1980 Jan;17(1):30–36. [PMC free article] [PubMed]
  • Musa EK, Desai N, Casewell MW. The survival of Acinetobacter calcoaceticus inoculated on fingertips and on formica. J Hosp Infect. 1990 Apr;15(3):219–227. [PubMed]
  • Nagler A, Pavel L, Naparstek E, Muggia-Sullam M, Slavin S. Typhlitis occurring in autologous bone marrow transplantation. Bone Marrow Transplant. 1992 Jan;9(1):63–64. [PubMed]
  • Neu HC. Bacterial resistance to fluoroquinolones. Rev Infect Dis. 1988 Jan-Feb;10 (Suppl 1):S57–S63. [PubMed]
  • Ng PC, Herrington RA, Beane CA, Ghoneim AT, Dear PR. An outbreak of acinetobacter septicaemia in a neonatal intensive care unit. J Hosp Infect. 1989 Nov;14(4):363–368. [PubMed]
  • Struelens MJ, Carlier E, Maes N, Serruys E, Quint WG, van Belkum A. Nosocomial colonization and infection with multiresistant Acinetobacter baumannii: outbreak delineation using DNA macrorestriction analysis and PCR-fingerprinting. J Hosp Infect. 1993 Sep;25(1):15–32. [PubMed]
  • Nowak A, Burkiewicz A, Kur J. PCR differentiation of seventeen genospecies of Acinetobacter. FEMS Microbiol Lett. 1995 Feb 15;126(2):181–187. [PubMed]
  • Obana Y. Pathogenic significance of Acinetobacter calcoaceticus: analysis of experimental infection in mice. Microbiol Immunol. 1986;30(7):645–657. [PubMed]
  • Obana Y, Nishino T, Tanino T. In-vitro and in-vivo activities of antimicrobial agents against Acinetobacter calcoaceticus. J Antimicrob Chemother. 1985 Apr;15(4):441–448. [PubMed]
  • Obara M, Nakae T. Mechanisms of resistance to beta-lactam antibiotics in Acinetobacter calcoaceticus. J Antimicrob Chemother. 1991 Dec;28(6):791–800. [PubMed]
  • Pagel JE, Seyfried PL. Numerical taxonomy of aquatic Acinetobacter isolates. J Gen Microbiol. 1976 Aug;96(2):220–232. [PubMed]
  • Patterson JE, Vecchio J, Pantelick EL, Farrel P, Mazon D, Zervos MJ, Hierholzer WJ., Jr Association of contaminated gloves with transmission of Acinetobacter calcoaceticus var. anitratus in an intensive care unit. Am J Med. 1991 Nov;91(5):479–483. [PubMed]
  • Peacock JE, Jr, Sorrell L, Sottile FD, Price LE, Rutala WA. Nosocomial respiratory tract colonization and infection with aminoglycoside-resistant Acinetobacter calcoaceticus var anitratus: epidemiologic characteristics and clinical significance. Infect Control Hosp Epidemiol. 1988 Jul;9(7):302–308. [PubMed]
  • Pedersen MM, Marso E, Pickett MJ. Nonfermentative bacilli associated with man. 3. Pathogenicity and antibiotic susceptibility. Am J Clin Pathol. 1970 Aug;54(2):178–192. [PubMed]
  • Pedraza F, Andreu A, Saune M, Moreno A, Ramírez L, García L. Brote urinario de Acinetobacter baumanii en una unidad de lesionados medulares. An Med Interna. 1993 Feb;10(2):55–58. [PubMed]
  • Picard B, Goullet P, Bouvet PJ, Decoux G, Denis JB. Characterization of bacterial genospecies by computer-assisted statistical analysis of enzyme electrophoretic data. Electrophoresis. 1989 Oct;10(10):680–685. [PubMed]
  • PIECHAUD D, PIECHAUD M, SECOND L. Variétes protéolytiques de Moraxella lwoffi et de Moraxella glucidolytica (Bact. anitratum). Ann Inst Pasteur (Paris) 1956 Apr;90(4):517–522. [PubMed]
  • Poh CL, Loh GK. Enzymatic profile of clinical isolates of Acinetobacter calcoaceticus. Med Microbiol Immunol. 1985;174(1):29–33. [PubMed]
  • Reboli AC, Houston ED, Monteforte JS, Wood CA, Hamill RJ. Discrimination of epidemic and sporadic isolates of Acinetobacter baumannii by repetitive element PCR-mediated DNA fingerprinting. J Clin Microbiol. 1994 Nov;32(11):2635–2640. [PMC free article] [PubMed]
  • Regev R, Dolfin T, Zelig I, Givoni S, Wolach B. Acinetobacter septicemia: a threat to neonates? Special aspects in a neonatal intensive care unit. Infection. 1993 Nov-Dec;21(6):394–396. [PubMed]
  • Retailliau HF, Hightower AW, Dixon RE, Allen JR. Acinetobacter calcoaceticus: a nosocomial pathogen with an unusual seasonal pattern. J Infect Dis. 1979 Mar;139(3):371–375. [PubMed]
  • Rolston K, Guan Z, Bodey GP, Elting L. Acinetobacter calcoaceticus septicemia in patients with cancer. South Med J. 1985 Jun;78(6):647–651. [PubMed]
  • Rosenberg M, Bayer EA, Delarea J, Rosenberg E. Role of Thin Fimbriae in Adherence and Growth of Acinetobacter calcoaceticus RAG-1 on Hexadecane. Appl Environ Microbiol. 1982 Oct;44(4):929–937. [PMC free article] [PubMed]
  • Rosenthal S, Tager IB. Prevalence of gram-negative rods in the normal pharyngeal flora. Ann Intern Med. 1975 Sep;83(3):355–357. [PubMed]
  • Rosenthal SL. Sources of pseudomonas and acinetobacter species found in human culture materials. Am J Clin Pathol. 1974 Dec;62(6):807–811. [PubMed]
  • Sacks-Berg A, Calubiran OV, Epstein HY, Cunha BA. Sepsis associated with transhepatic cholangiography. J Hosp Infect. 1992 Jan;20(1):43–50. [PubMed]
  • Sakata H, Fujita K, Maruyama S, Kakehashi H, Mori Y, Yoshioka H. Acinetobacter calcoaceticus biovar anitratus septicaemia in a neonatal intensive care unit: epidemiology and control. J Hosp Infect. 1989 Jul;14(1):15–22. [PubMed]
  • Santos Ferreira MO, Vieu JF, Klein B. Phage-types and susceptibility to 26 antibiotics of nosocomial strains of Acinetobacter isolated in Portugal. J Int Med Res. 1984;12(6):364–368. [PubMed]
  • Sato K, Nakae T. Outer membrane permeability of Acinetobacter calcoaceticus and its implication in antibiotic resistance. J Antimicrob Chemother. 1991 Jul;28(1):35–45. [PubMed]
  • Scaife W, Young HK, Paton RH, Amyes SG. Transferable imipenem-resistance in Acinetobacter species from a clinical source. J Antimicrob Chemother. 1995 Sep;36(3):585–586. [PubMed]
  • Schaberg DR, Culver DH, Gaynes RP. Major trends in the microbial etiology of nosocomial infection. Am J Med. 1991 Sep 16;91(3B):72S–75S. [PubMed]
  • Schaub IG, Hauber FD. A Biochemical and Serological Study of a Group of Identical Unidentifiable Gram-negative Bacilli from Human Sources. J Bacteriol. 1948 Oct;56(4):379–385. [PMC free article] [PubMed]
  • Seifert H, Baginski R, Schulze A, Pulverer G. The distribution of Acinetobacter species in clinical culture materials. Zentralbl Bakteriol. 1993 Nov;279(4):544–552. [PubMed]
  • Seifert H, Baginski R, Schulze A, Pulverer G. Antimicrobial susceptibility of Acinetobacter species. Antimicrob Agents Chemother. 1993 Apr;37(4):750–753. [PMC free article] [PubMed]
  • Seifert H, Richter W, Pulverer G. Clinical and bacteriological features of relapsing shunt-associated meningitis due to Acinetobacter baumannii. Eur J Clin Microbiol Infect Dis. 1995 Feb;14(2):130–134. [PubMed]
  • Seifert H, Schulze A, Baginski R, Pulverer G. Plasmid DNA fingerprinting of Acinetobacter species other than Acinetobacter baumannii. J Clin Microbiol. 1994 Jan;32(1):82–86. [PMC free article] [PubMed]
  • Seifert H, Schulze A, Baginski R, Pulverer G. Comparison of four different methods for epidemiologic typing of Acinetobacter baumannii. J Clin Microbiol. 1994 Jul;32(7):1816–1819. [PMC free article] [PubMed]
  • Seifert H, Strate A, Schulze A, Pulverer G. Vascular catheter-related bloodstream infection due to Acinetobacter johnsonii (formerly Acinetobacter calcoaceticus var. lwoffi): report of 13 cases. Clin Infect Dis. 1993 Oct;17(4):632–636. [PubMed]
  • Selander RK, Caugant DA, Ochman H, Musser JM, Gilmour MN, Whittam TS. Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics. Appl Environ Microbiol. 1986 May;51(5):873–884. [PMC free article] [PubMed]
  • Shannon KP, Phillips I, King BA. Aminoglycoside resistance among Enterobacteriaceae and Acinetobacter species. J Antimicrob Chemother. 1978 Mar;4(2):131–142. [PubMed]
  • Shaw KJ, Hare RS, Sabatelli FJ, Rizzo M, Cramer CA, Naples L, Kocsi S, Munayyer H, Mann P, Miller GH, et al. Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates. Antimicrob Agents Chemother. 1991 Nov;35(11):2253–2261. [PMC free article] [PubMed]
  • Shaw KJ, Rather PN, Hare RS, Miller GH. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. Microbiol Rev. 1993 Mar;57(1):138–163. [PMC free article] [PubMed]
  • Sherertz RJ, Sullivan ML. An outbreak of infections with Acinetobacter calcoaceticus in burn patients: contamination of patients' mattresses. J Infect Dis. 1985 Feb;151(2):252–258. [PubMed]
  • Siegman-Igra Y, Bar-Yosef S, Gorea A, Avram J. Nosocomial acinetobacter meningitis secondary to invasive procedures: report of 25 cases and review. Clin Infect Dis. 1993 Nov;17(5):843–849. [PubMed]
  • Smego RA., Jr Endemic nosocomial Acinetobacter calcoaceticus bacteremia. Clinical significance, treatment, and prognosis. Arch Intern Med. 1985 Dec;145(12):2174–2179. [PubMed]
  • Smith AW, Freeman S, Minett WG, Lambert PA. Characterisation of a siderophore from Acinetobacter calcoaceticus. FEMS Microbiol Lett. 1990 Jun 15;58(1):29–32. [PubMed]
  • Smith PW, Massanari RM. Room humidifiers as the source of Acinetobacter infections. JAMA. 1977 Feb 21;237(8):795–797. [PubMed]
  • Somerville DA, Noble WC. A note on the gram negative bacilli of human skin. Rev Eur Etud Clin Biol. 1970 Jun-Jul;15(6):669–671. [PubMed]
  • Struelens MJ, Carlier E, Maes N, Serruys E, Quint WG, van Belkum A. Nosocomial colonization and infection with multiresistant Acinetobacter baumannii: outbreak delineation using DNA macrorestriction analysis and PCR-fingerprinting. J Hosp Infect. 1993 Sep;25(1):15–32. [PubMed]
  • Tankovic J, Legrand P, De Gatines G, Chemineau V, Brun-Buisson C, Duval J. Characterization of a hospital outbreak of imipenem-resistant Acinetobacter baumannii by phenotypic and genotypic typing methods. J Clin Microbiol. 1994 Nov;32(11):2677–2681. [PMC free article] [PubMed]
  • Thurm V, Ritter E. Genetic diversity and clonal relationships of Acinetobacter baumannii strains isolated in a neonatal ward: epidemiological investigations by allozyme, whole-cell protein and antibiotic resistance analysis. Epidemiol Infect. 1993 Dec;111(3):491–498. [PMC free article] [PubMed]
  • Tilley PA, Roberts FJ. Bacteremia with Acinetobacter species: risk factors and prognosis in different clinical settings. Clin Infect Dis. 1994 Jun;18(6):896–900. [PubMed]
  • Tjernberg I, Ursing J. Clinical strains of Acinetobacter classified by DNA-DNA hybridization. APMIS. 1989 Jul;97(7):595–605. [PubMed]
  • Torres A, Aznar R, Gatell JM, Jiménez P, González J, Ferrer A, Celis R, Rodriguez-Roisin R. Incidence, risk, and prognosis factors of nosocomial pneumonia in mechanically ventilated patients. Am Rev Respir Dis. 1990 Sep;142(3):523–528. [PubMed]
  • Towner KJ. Chromosome mapping in Acinetobacter calcoaceticus. J Gen Microbiol. 1978 Feb;104(2):175–180. [PubMed]
  • Towner KJ. Transposon-directed mutagenesis and chromosome mobilization in Acinetobacter calcoaceticus EBF65/65. Genet Res. 1983 Feb;41(1):97–102. [PubMed]
  • Towner KJ, Chopade BA. Biotyping of Acinetobacter calcoaceticus using the API 2ONE system. J Hosp Infect. 1987 Sep;10(2):145–151. [PubMed]
  • Towner KJ, Vivian A. RP4-mediated conjugation in Acinetobacter calcoaceticus. J Gen Microbiol. 1976 Apr;93(2):355–360. [PubMed]
  • Traub WH. Acinetobacter baumannii serotyping for delineation of outbreaks of nosocomial cross-infection. J Clin Microbiol. 1989 Dec;27(12):2713–2716. [PMC free article] [PubMed]
  • Traub WH. Serotyping of clinical isolates of Acinetobacter: serovars of genospecies 3. Zentralbl Bakteriol. 1990 May;273(1):12–23. [PubMed]
  • Traub WH, Spohr M. Antimicrobial drug susceptibility of clinical isolates of Acinetobacter species (A. baumannii, A. haemolyticus, genospecies 3, and genospecies 6). Antimicrob Agents Chemother. 1989 Sep;33(9):1617–1619. [PMC free article] [PubMed]
  • Urban C, Go E, Mariano N, Berger BJ, Avraham I, Rubin D, Rahal JJ. Effect of sulbactam on infections caused by imipenem-resistant Acinetobacter calcoaceticus biotype anitratus. J Infect Dis. 1993 Feb;167(2):448–451. [PubMed]
  • Valdez JM, Asperilla MO, Smego RA., Jr Acinetobacter peritonitis in patients receiving continuous ambulatory peritoneal dialysis. South Med J. 1991 May;84(5):607–610. [PubMed]
  • Vandenbroucke-Grauls CM, Kerver AJ, Rommes JH, Jansen R, den Dekker C, Verhoef J. Endemic Acinetobacter anitratus in a surgical intensive care unit: mechanical ventilators as reservoir. Eur J Clin Microbiol Infect Dis. 1988 Aug;7(4):485–489. [PubMed]
  • Vaneechoutte M, Dijkshoorn L, Tjernberg I, Elaichouni A, de Vos P, Claeys G, Verschraegen G. Identification of Acinetobacter genomic species by amplified ribosomal DNA restriction analysis. J Clin Microbiol. 1995 Jan;33(1):11–15. [PMC free article] [PubMed]
  • Versalovic J, Koeuth T, Lupski JR. Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes. Nucleic Acids Res. 1991 Dec 25;19(24):6823–6831. [PMC free article] [PubMed]
  • Vila J, Almela M, Jimenez de Anta MT. Laboratory investigation of hospital outbreak caused by two different multiresistant Acinetobacter calcoaceticus subsp. anitratus strains. J Clin Microbiol. 1989 May;27(5):1086–1089. [PMC free article] [PubMed]
  • Vila J, Marcos A, Marco F, Abdalla S, Vergara Y, Reig R, Gomez-Lus R, Jimenez de Anta T. In vitro antimicrobial production of beta-lactamases, aminoglycoside-modifying enzymes, and chloramphenicol acetyltransferase by and susceptibility of clinical isolates of Acinetobacter baumannii. Antimicrob Agents Chemother. 1993 Jan;37(1):138–141. [PMC free article] [PubMed]
  • Warskow AL, Juni E. Nutritional requirements of Acinetobacter strains isolated from soil, water, and sewage. J Bacteriol. 1972 Nov;112(2):1014–1016. [PMC free article] [PubMed]
  • Weaver RE, Actis LA. Identification of Acinetobacter species. J Clin Microbiol. 1994 Jul;32(7):1833–1833. [PMC free article] [PubMed]
  • Weernink A, Severin WP, Tjernberg I, Dijkshoorn L. Pillows, an unexpected source of Acinetobacter. J Hosp Infect. 1995 Mar;29(3):189–199. [PubMed]
  • Wise KA, Tosolini FA. Epidemiological surveillance of Acinetobacter species. J Hosp Infect. 1990 Nov;16(4):319–329. [PubMed]
  • Zabel RW, Winegarden T, Holland EJ, Doughman DJ. Acinetobacter corneal ulcer after penetrating keratoplasty. Am J Ophthalmol. 1989 Jun 15;107(6):677–678. [PubMed]

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