• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of aacPermissionsJournals.ASM.orgJournalAAC ArticleJournal InfoAuthorsReviewers
Antimicrob Agents Chemother. Apr 1988; 32(4): 598–600.
PMCID: PMC172230

Activities of Nigerian chewing stick extracts against Bacteroides gingivalis and Bacteroides melaninogenicus.


The in vitro activities of extracts of Nigerian chewing sticks against Bacteroides gingivalis and B. melaninogenicus are presented. The greatest inhibitory action was produced by Serindeia werneckei, whereas Fagara zanthoxyloides produced no appreciable inhibitory effect. A generally good correlation was found between the killing curves and MICs. Only extracts of Anogeissus leiocarpus showed acute toxicity in mice.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (497K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Dzink JL, Socransky SS. Comparative in vitro activity of sanguinarine against oral microbial isolates. Antimicrob Agents Chemother. 1985 Apr;27(4):663–665. [PMC free article] [PubMed]
  • Isaacs SL. Nonphysician distribution of contraception in Latin America and the Caribbean. Fam Plann Perspect. 1975 Jul-Aug;7(4):158–164. [PubMed]
  • Loesche WJ, Hockett RN, Syed SA. The predominant cultivable flora of tooth surface plaque removed from institutionalized subjects. Arch Oral Biol. 1972 Sep;17(9):1311–1325. [PubMed]
  • Loesche WJ, Syed SA, Schmidt E, Morrison EC. Bacterial profiles of subgingival plaques in periodontitis. J Periodontol. 1985 Aug;56(8):447–456. [PubMed]
  • Manley JL, Limongelli WA, Williams AC. The chewing stick: its uses and relationship to oral health. J Prev Dent. 1975 Sep-Oct;2(5):7–9. [PubMed]
  • Odebiyi OO, Sofowora EA. Antimicrobial alkaloids from a Nigerian chewing stick (Fagara zanthoxyloides). Planta Med. 1979 Jul;36(3):204–207. [PubMed]
  • Rotimi VO, Mosadomi HA. The effect of crude extracts of nine African chewing sticks on oral anaerobes. J Med Microbiol. 1987 Feb;23(1):55–60. [PubMed]
  • Slots J. The predominant cultivable microflora of advanced periodontitis. Scand J Dent Res. 1977 Jan-Feb;85(2):114–121. [PubMed]
  • White D, Mayrand D. Association of oral Bacteroides with gingivitis and adult periodontitis. J Periodontal Res. 1981 May;16(3):259–265. [PubMed]
  • Wolinsky LE, Sote EO. Isolation of natural plaque-inhibiting substances from 'Nigerian chewing sticks'. Caries Res. 1984;18(3):216–225. [PubMed]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...