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Arch Dis Child. Nov 1997; 77(5): 406–409.
PMCID: PMC1717368

Community study of toxoplasma antibodies in urban and rural schoolchildren aged 4 to 18 years

Abstract



To estimate the prevalence of toxoplasma antibodies in schoolchildren and their association with clinical and environmental data, antibody titres were measured in 1276 children aged 4 to 18 years attending primary and secondary schools. Environmental and clinical data were obtained by questionnaire. Altogether 12.8% (163/1276) of children had antibodies to Toxoplasma gondii with no difference between the sexes. Seroprevalence was higher in country children (16.6% (50/302)) than town children (10.2% (75/737)). The proportion testing positive increased with age in both town and country children. No association with cat ownership was found. Toxoplasma seropositivity was associated with a positive toxocara titre, having had a bitch whelp in the past two years, and having an unwormed dog at home. Lack of energy or tiredness in the last 12 months were the only clinical features associated with a positive titre.

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Selected References

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  • Huldt G, Lagercrantz R, Sheehe PR. On the epidemiology of human toxoplasmosis in Scandinavia especially in children. Acta Paediatr Scand. 1979 Sep;68(5):745–749. [PubMed]
  • Holland CV, O'Lorcain P, Taylor MR, Kelly A. Sero-epidemiology of toxocariasis in school children. Parasitology. 1995 Jun;110(Pt 5):535–545. [PubMed]
  • Parker SP, Cubitt WD. Modified latex agglutination test for antibodies to Toxoplasma gondii in eluates from Guthrie cards. J Clin Pathol. 1992 Oct;45(10):907–909. [PMC free article] [PubMed]
  • Taylor MR, Holland CV, Spencer R, Jackson JF, O'Connor GI, O'Donnell JR. Haematological reference ranges for schoolchildren. Clin Lab Haematol. 1997 Mar;19(1):1–15. [PubMed]
  • Johnson J, Duffy K, New L, Holliman RE, Chessum BS, Fleck DG. Direct agglutination test and other assays for measuring antibodies to Toxoplasma gondii. J Clin Pathol. 1989 May;42(5):536–541. [PMC free article] [PubMed]
  • Patel B, Holliman RE. Antibodies to Toxoplasma gondii in eluates from filter paper blood specimens. Br J Biomed Sci. 1994 Jun;51(2):104–108. [PubMed]
  • Walker J, Nokes DJ, Jennings R. Longitudinal study of Toxoplasma seroprevalence in South Yorkshire. Epidemiol Infect. 1992 Feb;108(1):99–106. [PMC free article] [PubMed]
  • Etheredge GD, Frenkel JK. Human Toxoplasma infection in Kuna and Embera children in the Bayano and San Blas, eastern Panama. Am J Trop Med Hyg. 1995 Nov;53(5):448–457. [PubMed]
  • Frenkel JK, Hassanein KM, Hassanein RS, Brown E, Thulliez P, Quintero-Nunez R. Transmission of Toxoplasma gondii in Panama City, Panama: a five-year prospective cohort study of children, cats, rodents, birds, and soil. Am J Trop Med Hyg. 1995 Nov;53(5):458–468. [PubMed]
  • French JG, Messinger HB, MacCarthy J. A study of Toxoplasma gondii infection in farm and non-farm groups in the same geographic location. Am J Epidemiol. 1970 Feb;91(2):185–191. [PubMed]
  • BEATTIE CP. Clinical and epidemiological aspects of toxoplasmosis. Trans R Soc Trop Med Hyg. 1957 Mar;51(2):96–103. [PubMed]
  • BEVERLEY JK, BEATTIE CP. Glandular toxoplasmosis; a survey of 30 cases. Lancet. 1958 Aug 23;2(7043):379–384. [PubMed]

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