• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of cdliPermissionsJournals.ASM.orgAEM ArticleJournal InfoAuthorsReviewers
Clin Diagn Lab Immunol. May 1996; 3(3): 361–362.
PMCID: PMC170348

Time to peak serum antibody response to influenza vaccine in the elderly.


The earliest time at which serum antibody peaks following administration of influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 2 and 4 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91(H1N1), A/Shangdong/9/93(H3N2), and B/Panama/45/90 was used. The hemagglutination inhibition antibody titers at 2 weeks after vaccination were identical to the hemagglutination inhibition antibody titers at 4 weeks for all three vaccine components.

Full Text

The Full Text of this article is available as a PDF (142K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Clements ML, Murphy BR. Development and persistence of local and systemic antibody responses in adults given live attenuated or inactivated influenza A virus vaccine. J Clin Microbiol. 1986 Jan;23(1):66–72. [PMC free article] [PubMed]
  • Foy HM, Cooney MK, McMahan R. A Hong Kong influenza immunity three years after immunization. JAMA. 1973 Nov 12;226(7):758–761. [PubMed]
  • Gross PA, Davis AE. Neutralization test in influenza: use in individuals without hemagglutination inhibition antibody. J Clin Microbiol. 1979 Sep;10(3):382–384. [PMC free article] [PubMed]
  • Gross PA, Ennis FA, Gaerlan PF, Denson LJ, Denning CR, Schiffman D. A controlled double-blind comparison of reactogenicity, immunogenicity, and protective efficacy of whole-virus and split-product influenza vaccines in children. J Infect Dis. 1977 Nov;136(5):623–632. [PubMed]
  • Rastogi S, Gross PA, Bonelli J, Dran S, Levandowski RA, Russo C, Weksler ME, Kaye D, Levison M, Abrutyn E, et al. Time to peak serum antibody response to influenza vaccine. Clin Diagn Lab Immunol. 1995 Jan;2(1):120–121. [PMC free article] [PubMed]

Articles from Clinical and Diagnostic Laboratory Immunology are provided here courtesy of American Society for Microbiology (ASM)


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...