• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of procbhomepageaboutsubmitalertseditorial board
Proc Biol Sci. Aug 7, 2003; 270(Suppl 1): S96–S99.
PMCID: PMC1698023

Barcoding animal life: cytochrome c oxidase subunit 1 divergences among closely related species.

Abstract

With millions of species and their life-stage transformations, the animal kingdom provides a challenging target for taxonomy. Recent work has suggested that a DNA-based identification system, founded on the mitochondrial gene, cytochrome c oxidase subunit 1 (COI), can aid the resolution of this diversity. While past work has validated the ability of COI sequences to diagnose species in certain taxonomic groups, the present study extends these analyses across the animal kingdom. The results indicate that sequence divergences at COI regularly enable the discrimination of closely allied species in all animal phyla except the Cnidaria. This success in species diagnosis reflects both the high rates of sequence change at COI in most animal groups and constraints on intraspecific mitochondrial DNA divergence arising, at least in part, through selective sweeps mediated via interactions with the nuclear genome.

Full Text

The Full Text of this article is available as a PDF (75K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Avise JC, Walker D. Species realities and numbers in sexual vertebrates: perspectives from an asexually transmitted genome. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):992–995. [PMC free article] [PubMed]
  • Ballard JW. Comparative genomics of mitochondrial DNA in Drosophila simulans. J Mol Evol. 2000 Jul;51(1):64–75. [PubMed]
  • Barrientos A, Müller S, Dey R, Wienberg J, Moraes CT. Cytochrome c oxidase assembly in primates is sensitive to small evolutionary variations in amino acid sequence. Mol Biol Evol. 2000 Oct;17(10):1508–1519. [PubMed]
  • Blaxter Mark. Molecular systematics: Counting angels with DNA. Nature. 2003 Jan 9;421(6919):122–124. [PubMed]
  • Jamieson Glyn G, France Michael, Watson David I. Results of laparoscopic antireflux operations in patients who have Barrett's esophagus. Chest Surg Clin N Am. 2002 Feb;12(1):149–155. [PubMed]
  • Gerber AS, Loggins R, Kumar S, Dowling TE. Does nonneutral evolution shape observed patterns of DNA variation in animal mitochondrial genomes? Annu Rev Genet. 2001;35:539–566. [PubMed]
  • Godfray H Charles J. Challenges for taxonomy. Nature. 2002 May 2;417(6884):17–19. [PubMed]
  • Hebert Paul D N, Cywinska Alina, Ball Shelley L, deWaard Jeremy R. Biological identifications through DNA barcodes. Proc Biol Sci. 2003 Feb 7;270(1512):313–321. [PMC free article] [PubMed]
  • Inagaki Y, Ehara M, Watanabe KI, Hayashi-Ishimaru Y, Ohama T. Directionally evolving genetic code: the UGA codon from stop to tryptophan in mitochondria. J Mol Evol. 1998 Oct;47(4):378–384. [PubMed]
  • Johns GC, Avise JC. A comparative summary of genetic distances in the vertebrates from the mitochondrial cytochrome b gene. Mol Biol Evol. 1998 Nov;15(11):1481–1490. [PubMed]
  • Schmidt TR, Wu W, Goodman M, Grossman LI. Evolution of nuclear- and mitochondrial-encoded subunit interaction in cytochrome c oxidase. Mol Biol Evol. 2001 Apr;18(4):563–569. [PubMed]
  • Shearer TL, Van Oppen MJH, Romano SL, Wörheide G. Slow mitochondrial DNA sequence evolution in the Anthozoa (Cnidaria). Mol Ecol. 2002 Dec;11(12):2475–2487. [PubMed]
  • Willett CS, Burton RS. Viability of cytochrome c genotypes depends on cytoplasmic backgrounds in Tigriopus californicus. Evolution. 2001 Aug;55(8):1592–1599. [PubMed]
  • Wu W, Schmidt TR, Goodman M, Grossman LI. Molecular evolution of cytochrome c oxidase subunit I in primates: is there coevolution between mitochondrial and nuclear genomes? Mol Phylogenet Evol. 2000 Nov;17(2):294–304. [PubMed]

Articles from Proceedings of the Royal Society B: Biological Sciences are provided here courtesy of The Royal Society

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...