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Am J Public Health. 1993 December; 83(12): 1712–1716.
PMCID: PMC1694912

Estimates of the US health impact of influenza.


OBJECTIVES. Data from the Tecumseh Community Health Study were used to estimate excess morbidity owing to influenza, and results were compared with estimates made previously using different methodology for an Institute of Medicine report. METHODS. Study participants from Tecumseh, Michigan, were classified as infected or noninfected based on laboratory results. The excess numbers of respiratory illnesses, respiratory illness days, and bed and restricted activity days experienced by the infected compared with the noninfected were estimated. RESULTS. The number of excess influenza-related respiratory illnesses was lower than that estimated in the Institute of Medicine report, in which all illnesses of certain characteristics occurring during an influenza season were attributed to influenza. It is now estimated that the US population under 20 years of age experiences a yearly average of 13.8 to 16.0 million influenza-related excess respiratory illnesses; for older individuals, the yearly estimate is 4.1 to 4.4 million excess illnesses. CONCLUSIONS. For public health purposes, estimates of excess morbidity as well as of total morbidity associated with influenza should be used in setting health priorities.

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  • Monto AS, Cavallaro JJ. The Tecumseh study of respiratory illness. II. Patterns of occurrence of infection with respiratory pathogens, 1965-1969. Am J Epidemiol. 1971 Sep;94(3):280–289. [PubMed]
  • Monto AS, Lim SK. The Tecumseh study of respiratory illness. 3. Incidence and periodicity of respiratory syncytial virus and Mycoplasma pneumoniae infections. Am J Epidemiol. 1971 Sep;94(3):290–301. [PubMed]
  • Monto AS, Koopman JS, Longini IM., Jr Tecumseh study of illness. XIII. Influenza infection and disease, 1976-1981. Am J Epidemiol. 1985 Jun;121(6):811–822. [PubMed]
  • Monto AS, Napier JA, Metzner HL. The Tecumseh study of respiratory illness. I. Plan of study and observations on syndromes of acute respiratory disease. Am J Epidemiol. 1971 Sep;94(3):269–279. [PubMed]
  • Monto AS, Kioumehr F. The Tecumseh Study of Respiratory Illness. IX. Occurence of influenza in the community, 1966--1971. Am J Epidemiol. 1975 Dec;102(6):553–563. [PubMed]
  • Monto AS, Maassab HF. Ether treatment of type B influenza virus antigen for the hemagglutination inhibition test. J Clin Microbiol. 1981 Jan;13(1):54–57. [PMC free article] [PubMed]
  • Longini IM, Jr, Koopman JS, Haber M, Cotsonis GA. Statistical inference for infectious diseases. Risk-specific household and community transmission parameters. Am J Epidemiol. 1988 Oct;128(4):845–859. [PubMed]
  • Glezen WP. Serious morbidity and mortality associated with influenza epidemics. Epidemiol Rev. 1982;4:25–44. [PubMed]
  • Lui KJ, Kendal AP. Impact of influenza epidemics on mortality in the United States from October 1972 to May 1985. Am J Public Health. 1987 Jun;77(6):712–716. [PMC free article] [PubMed]
  • FRANCIS T, Jr, DAVENPORT FM, HENNESSY AV. A serological recapitulation of human infection with different strains of influenza virus. Trans Assoc Am Physicians. 1953;66:231–239. [PubMed]
  • Sonoguchi T, Naito H, Hara M, Takeuchi Y, Fukumi H. Cross-subtype protection in humans during sequential, overlapping, and/or concurrent epidemics caused by H3N2 and H1N1 influenza viruses. J Infect Dis. 1985 Jan;151(1):81–88. [PubMed]
  • Ackerman E, Longini IM, Jr, Seaholm SK, Hedin AS. Simulation of mechanisms of viral interference in influenza. Int J Epidemiol. 1990 Jun;19(2):444–454. [PubMed]

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