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Am J Hum Genet. 1993 Jan; 52(1): 96–98.
PMCID: PMC1682100

The morquio A syndrome (mucopolysaccharidosis IVA) gene maps to 16q24.3.


The gene for N-acetylgalactosamine-6-sulfatase, the deficiency of which results in Morquio A syndrome (mucopolysaccharidosis type IVA), was assigned to chromosome 16 at band q24.3 by fluorescence in situ hybridization. Localization of this band was confirmed by PCR analysis of a somatic cell hybrid panel used for fine mapping of chromosome 16.

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Selected References

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  • Shows TB, Scrafford-Wolff LR, Brown JA, Meisler MH. GM1-gangliosidosis: chromosome 3 assignment of the beta-galactosidase-A gene (beta GALA). Somatic Cell Genet. 1979 Mar;5(2):147–158. [PubMed]
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