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Journal List > Br Med J > v.3(5977); Jul 26, 1975

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Br Med J. 1975 July 26; 3(5977): 195–197.
PMCID: PMC1674130
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Effect of new beta-adrenergic blocking agent, Atenolol (Tenormin), on pain frequency, trinitrin consumption, and exercise ability.
P Roy, L Day, and E Sowton
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Abstract
In 11 patients with severe angina pectoris a new beta-blocking drug, atenolol (Tenormin; I.C.I.66082), was found in a double-blind randomized trial to reduce significantly the frequency of anginal attacks (P less than 0-001) and the amount of trinitrin consumed (P less than 0-03) in comparison with practolol and placebo. There was no significant improvement in the patients' ability to exercise on the bicycle ergometer.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Gillam PM, Prichard BN. Propranolol in the therapy of angina pectoris. Am J Cardiol. 1966 Sep;18(3):366–369. [PubMed]
  • KEELAN P. DOUBLE-BLIND TRIAL OF PROPRANOLOL (INDERAL) IN ANGINA PECTORIS. Br Med J. 1965 Apr 3;1(5439):897–898. [PubMed]
  • Wilson DF, Turner AS. Trasicor (39,089/Ba) in angina pectoris. A single-blind trial. N Z Med J. 1968 Mar;67(430):406–407. [PubMed]
  • Aström H, Vallin H. Effect of a new beta-adrenergic blocking agent, ICI 66o82, on exercise haemodynamics and airway resistance in angina pectoris. Br Heart J. 1974 Dec;36(12):1194–1200. [PubMed]
  • MCNEILL RS. EFFECT OF A BETA-ADRENERGIC-BLOCKING AGENT, PROPRANOLOL, ON ASTHMATICS. Lancet. 1964 Nov 21;2(7369):1101–1102. [PubMed]
  • Hamer J, Sowton E. Cardiac output after beta-adrenergic blockade in ischaemic heart disease. Br Heart J. 1965 Nov;27(6):892–895. [PubMed]
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