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Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate. R J Bull PMCID: PMC1637759 Is Cited by the Following Articles in this Archive: Uncertainties in Biologically-Based Modeling of Formaldehyde-Induced Respiratory Cancer Risk: Identification of Key Issues Ravi P. Subramaniam, Chao Chen, Kenny S. Crump, Danielle DeVoney, John F. Fox, Christopher J. Portier, Paul M. Schlosser, Chad M. Thompson, and Paul White PMCID: PMC2719764 Published in final edited form as: Risk Anal. 2008 August; 28(4): 907–923. Published online 2008 June 28. doi: 10.1111/j.1539-6924.2008.01083.x. Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid Edward A Lock, Celia J Reed, JoEllyn M McMillan, John R Oatis, Jr, and Rick G Schnellmann PMCID: PMC2645029 Published in final edited form as: Toxicology. 2007 February 12; 230(2-3): 234–243. Published online 2006 November 18. doi: 10.1016/j.tox.2006.11.055. Metabolism and Tissue Distribution of Orally Administered Trichloroethylene in Male and Female Rats: Identification of Glutathione- and Cytochrome P450-Derived Metabolites in Liver, Kidney, Blood and Urine Lawrence H. Lash, David A. Putt, and Jean C. Parker PMCID: PMC1474023 Published in final edited form as: J Toxicol Environ Health A. 2006 July; 69(13): 1285–1309. doi: 10.1080/15287390500360133. Application of Cryopreserved Human Hepatocytes in Trichloroethylene Risk
Assessment: Relative Disposition of Chloral Hydrate to Trichloroacetate
and Trichloroethanol Apryl Bronley-DeLancey, David C. McMillan, JoEllyn M. McMillan, David J. Jollow, Lawrence C. Mohr, and David G. Hoel PMCID: PMC1551986 Key Scientific Issues in the Health Risk Assessment of Trichloroethylene Weihsueh A. Chiu, Jane C. Caldwell, Nagalakshmi Keshava, and Cheryl Siegel Scott PMCID: PMC1570079 Key Issues in the Role of Peroxisome Proliferator–Activated Receptor Agonism and Cell Signaling in Trichloroethylene Toxicity Nagalakshmi Keshava and Jane C. Caldwell PMCID: PMC1570084 Issues in the Pharmacokinetics of Trichloroethylene and Its Metabolites Weihsueh A. Chiu, Miles S. Okino, John C. Lipscomb, and Marina V. Evans PMCID: PMC1570093 L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes? Arthur J L Cooper, Boris F Krasnikov, Etsuo Okuno, and Thomas M Jeitner PMCID: PMC1223738 In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane. Ivan D Dobrev, Melvin E Andersen, and Raymond S H Yang PMCID: PMC1241030 Dose-response analyses of the carcinogenic effects of trichloroethylene in experimental animals. L R Rhomberg PMCID: PMC1637760 Biologically based dose-response model for liver tumors induced by trichloroethylene. C W Chen PMCID: PMC1637764 Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene. M M Moore and K Harrington-Brock PMCID: PMC1637765 Modes of action of trichloroethylene for kidney tumorigenesis. L H Lash, J C Parker, and C S Scott PMCID: PMC1637767 Trichloroethylene health risks--state of the science. C S Scott and V J Cogliano PMCID: PMC1637768 Metabolism of trichloroethylene. L H Lash, J W Fisher, J C Lipscomb, and J C Parker PMCID: PMC1637769 Human variability and susceptibility to trichloroethylene. G M Pastino, W Y Yap, and M Carroquino PMCID: PMC1637770
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