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Arch Dis Child. 1980 January; 55(1): 43–45. | PMCID: PMC1626725 |
Serum ferritin, liver iron stores, and liver histology in children with thalassaemia. S de Virgiliis, G Sanna, G Cornacchia, F Argiolu, V Murgia, M Porcu, and A Cao Abstract Serum ferritin, liver iron stores, and liver histology were studied in 38 children with thalassaemia major who were being treated by regular blood transfusions. There was no correlation between serum ferritin levels and either the number of transfusions or the amount of iron deposited in the liver. However, for a given level of iron stores, ferritin levels were higher in patients with chronic hepatitis (including chronic aggressive and chronic persistent forms) than in those with hepatic siderosis only. We conclude that serum ferritin reflects tissue iron deposits in regularly transfused thalassaemic patients, only in the absence of hepatitis. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (387K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - Jacobs A, Miller F, Worwood M, Beamish MR, Wardrop CA. Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. Br Med J. 1972 Oct 28;4(5834):206–208. [PubMed]
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