|
|
Br Med J. 1974 October 12; 4(5936): 78–79. | PMCID: PMC1612188 |
Organ-specific Antibodies in Patients with Lichen Sclerosus S. K. Goolamali, E. W. Barnes, W. J. Irvine, and Sam Shuster Abstract Organ-specific antibodies were looked for in 26 patients with lichen sclerosus. Ten of the 25 female patients (40%) had organ-specific antibodies to thyroid cytoplasm and 11 (44%) had organ-specific antibodies to gastric parietal cells. Both values were significantly greater than those obtained in age-matched controls. None of the sera from patients with lichen sclerosus contained antibodies to steroid-producing tissues. No organ-specific antibodies were found in the one male patient. The findings suggest that lichen sclerosus may be related to an autoimmune process. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (372K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - Ardeman S, Chanarin I, Krafchik B, Singer W. Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders. Q J Med. 1966 Jul;35(139):421–431. [PubMed]
- Bor S, Feiwel M, Chanarin I. Vitiligo and its aetiological relationship to organ-specific autoimmune disease. Br J Dermatol. 1969 Feb;81(2):83–88. [PubMed]
- Britt RP, Bolton FG, Cull AC, Spray GH. Experience with a simplified method of radio-isotopic assay of serum vitamin B 12. Br J Haematol. 1969 May;16(5):457–464. [PubMed]
- Cunliffe WJ, Hall R, Newell DJ, Stevenson CJ. Vitiligo, thyroid disease and autoimmunity. Br J Dermatol. 1968 Mar;80(3):135–139. [PubMed]
- GOUDIE RB, ANDERSON JR, GRAY KG. Complement-fixing antithyroid antibodies in hospital patients with asymptomatic thyroid lesions. J Pathol Bacteriol. 1959 Apr;77(2):389–400. [PubMed]
- Irvine WJ, Chan MM, Scarth L. The further characterization of autoantibodies reactive with extra-adrenal steroid-producing cells in patients with adrenal disorders. Clin Exp Immunol. 1969 May;4(5):489–503. [PubMed]
- Irvine WJ, Clarke BF, Scarth L, Cullen DR, Duncan LJ. Thyroid and gastric autoimmunity in patients with diabetes mellitus. Lancet. 1970 Jul 25;2(7665):163–168. [PubMed]
- LERNER AB. Vitiligo. J Invest Dermatol. 1959 Feb;32(2,):285–310. [PubMed]
- Mathews JD, Whittingham S, Hooper BM, Mackay IR, Stenhouse NS. Association of autoantibodies with smoking, cardiovascular morbidity, and death in the Busselton population. Lancet. 1973 Oct 6;2(7832):754–758. [PubMed]
- Ungar B, Stocks AE, Martin FI, Whittingham S, Mackay IR. Intrinsic-factor antibody, parietal-cell antibody, and latent pernicious anaemia in diabetes mellitus. Lancet. 1968 Aug 24;2(7565):415–417. [PubMed]
|