
Improved glucose control in maturity-onset diabetes treated with high-carbohydrate-modified fat diet.
Abstract
Fourteen patients with established maturity-onset diabetes were treated as outpatients with a high-carbohydrate-(about 60% of total daily energy requirements)-modified fat diet (ratio of polyunsaturated fatty acids to other fatty acids greater than or equal to 1:1) for six weeks. Commercially available and acceptable cereal foods and tuberous vegetables high in both digestible and non-digestible carbohydrates were used. Simple sugars were restricted. Compared with their usual, low-carbohydrate diabetic diet this diet resulted in a fall in basal plasma glucose concentration (average of values measured at 0300, 0500, and 0700), mean preprandial plasma glucose concentration (average of values measured at 0800, 1230, and 1730), and percentage of glycosylated haemoglobin. Modifying dietary fat also decreased the fasting plasma cholesterol concentration. The findings suggest that it is no longer justifiable to prescribe a low-carbohydrate diet for maturity-onset diabetes.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (804K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hockaday TD, Hockaday JM, Mann JI, Turner RC. Prospective comparison of modified fat-high-carbohydrate with standard low-carbohydrate dietary advice in the treatment of diabetes: one year follow-up study. Br J Nutr. 1978 Mar;39(2):357–362. [PubMed]
- Brunzell JD, Lerner RL, Porte D, Jr, Bierman EL. Effect of a fat free, high carbohydrate diet on diabetic subjects with fasting hyperglycemia. Diabetes. 1974 Feb;23(2):138–142. [PubMed]
- Miranda PM, Horwitz DL. High-fiber diets in the treatment of diabetes mellitus. Ann Intern Med. 1978 Apr;88(4):482–486. [PubMed]
- Jenkins DJ, Goff DV, Leeds AR, Alberti KG, Wolever TM, Gassull MA, Hockaday TD. Unabsorbable carbohydrates and diabetes: Decreased post-prandial hyperglycaemia. Lancet. 1976 Jul 24;2(7978):172–174. [PubMed]
- Southgate DA, Bailey B, Collinson E, Walker AF. A guide to calculating intakes of dietary fibre. J Hum Nutr. 1976 Oct;30(5):303–313. [PubMed]
- Eggstein M, Kreutz FH. Eine neue Bestimmung der Neutralfette im Blutserum und Gewebe. I. Prinzip, Durchführung und Besprechung der Methode. Klin Wochenschr. 1966 Mar 1;44(5):262–267. [PubMed]
- Burstein M, Scholnick HR, Morfin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res. 1970 Nov;11(6):583–595. [PubMed]
- Moore RA, Oppert S, Eaton P, Mann JI. Triglyceride fatty acids confirm a change in dietary fat. Clin Endocrinol (Oxf) 1977 Aug;7(2):143–149. [PubMed]
- SCHLICHTKRULL J, MUNCK O, JERSILD M. THE M-VALVE, AN INDEX OF BLOOD-SUGAR CONTROL IN DIABETICS. Acta Med Scand. 1965 Jan;177:95–102. [PubMed]
- BRUNNER D, ALTMAN S, NELKEN L, REIDER J. THE RELATIVE ABSENCE OF VASCULAR DISEASE IN DIABETIC YEMENITE JEWS. I. A STUDY OF CLINICAL FINDINGS. Diabetes. 1964 May-Jun;13:268–277. [PubMed]
- Brunzell JD, Lerner RL, Hazzard WR, Porte D, Jr, Bierman EL. Improved glucose tolerance with high carbohydrate feeding in mild diabetes. N Engl J Med. 1971 Mar 11;284(10):521–524. [PubMed]
- Jenkins DJ, Wolever TM, Leeds AR, Gassull MA, Haisman P, Dilawari J, Goff DV, Metz GL, Alberti KG. Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity. Br Med J. 1978 May 27;1(6124):1392–1394. [PMC free article] [PubMed]
- Garcia MJ, McNamara PM, Gordon T, Kannel WB. Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study. Diabetes. 1974 Feb;23(2):105–111. [PubMed]
- ANTONIS A, BERSOHN I. The influence of diet on serumtriglycerides in South Africa white and Bantu prisoners. Lancet. 1961 Jan 7;1(7167):3–9. [PubMed]