• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of brmedjBMJ helping doctors make better decisionsSearchLatest content
Br Med J. Oct 27, 1979; 2(6197): 1031–1033.
PMCID: PMC1596809

Improving medication compliance: a randomised clinical trial.

Abstract

A medical monitor which recorded the date and hour each time a medicine bottle was opened was used to evaluate a programme for improving patients' compliance with their treatment. Eighty-two patients with glaucoma who had been prescribed pilocarpine eye drops three times daily to prevent visual loss were randomised into two groups. Both groups used the medication monitor during two 20-day periods, but before the second period the experimental group were given an education and tailoring programme in an attempt to improve their compliance. Nine patients missed the second treatment period and were excluded from the analysis. The patients in the experimental group showed significantly improved compliance when compared with the control group. The numbers of missed doses were reduced by about half, as was the proportion of time that exceeded the eight-hour dose intervals. Follow-up studies are needed to determine how long the improved compliance persists, but anyone considering setting up an education and tailoring programme should recognise the extent to which therapeutic efforts are wasted because of non-compliance.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (740K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Stewart RB, Cluff LE. A review of medication errors and compliance in ambulant patients. Clin Pharmacol Ther. 1972 Jul-Aug;13(4):463–468. [PubMed]
  • Sackett DL, Haynes RB, Gibson ES, Taylor DW, Roberts RS, Johnson AL. Hypertension control, compliance and science. Am Heart J. 1977 Nov;94(5):666–667. [PubMed]
  • Stason WB, Weinstein MC. Public-health rounds at the Harvard School of Public Health. Allocation of resources to manage hypertension. N Engl J Med. 1977 Mar 31;296(13):732–739. [PubMed]
  • Bain DJ. Patient knowledge and the content of the consultation in general practice. Med Educ. 1977 Sep;11(5):347–350. [PubMed]
  • Hellström K, Leijd B. Vad vet patienter om sina sjukdomar och deras medikamentella behandling. Lakartidningen. 1976 Mar 10;73(11):968–970. [PubMed]
  • Sackett DL, Haynes RB, Gibson ES, Hackett BC, Taylor DW, Roberts RS, Johnson AL. Randomised clinical trial of strategies for improving medication compliance in primary hypertension. Lancet. 1975 May 31;1(7918):1205–1207. [PubMed]
  • Ley P, Jain VK, Skilbeck CE. A method for decreasing patients' medication errors. Psychol Med. 1976 Nov;6(4):599–601. [PubMed]
  • Haynes RB, Sackett DL, Gibson ES, Taylor DW, Hackett BC, Roberts RS, Johnson AL. Improvement of medication compliance in uncontrolled hypertension. Lancet. 1976 Jun 12;1(7972):1265–1268. [PubMed]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • Compound
    Compound
    PubChem Compound links
  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles
  • Substance
    Substance
    PubChem Substance links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...