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Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants
Patricia S Fletcher, Gregory S Wallace, Pedro MM Mesquita, Robin J Shattock
Retrovirology. 2006; 3: 46. Published online 2006 August 1. doi: 10.1186/1742-4690-3-46
PMCID:
PMC1590048
Abstract Full Text PDF–746K

Is Cited by the Following 22 Articles in this Archive:

Inhibition of HIV-1 Infection in Ex Vivo Cervical Tissue Model of Human Vagina by Palmitic Acid; Implications for a Microbicide Development
Xudong Lin, Elena E. Paskaleva, William Chang, Alexander Shekhtman, Mario Canki
PLoS One. 2011; 6(9): e24803. Published online 2011 September 19. doi: 10.1371/journal.pone.0024803
PMCID:
PMC3176227
Abstract Full Text PDF–248K
Decoding the Membrane Activity of the Cyclotide Kalata B1: THE IMPORTANCE OF PHOSPHATIDYLETHANOLAMINE PHOSPHOLIPIDS AND LIPID ORGANIZATION ON HEMOLYTIC AND ANTI-HIV ACTIVITIES
Sónia Troeira Henriques, Yen-Hua Huang, K. Johan Rosengren, Henri G. Franquelim, Filomena A. Carvalho, Adam Johnson, Secondo Sonza, Gilda Tachedjian, Miguel A. R. B. Castanho, Norelle L. Daly, David J. Craik
J Biol Chem. 2011 July 8; 286(27): 24231–24241. Published online 2011 May 16. doi: 10.1074/jbc.M111.253393
PMCID:
PMC3129204
Free in PMC on 2012/07/08
Enzymatic Triggered Release of an HIV-1 Entry Inhibitor from Prostate Specific Antigen Degradable Microparticles
Meredith R. Clark, Hyder A. Aliyar, Chang-won Lee, Julie I. Jay, Kavita M. Gupta, Karen M. Watson, Russell J. Stewart, Robert W. Buckheit, Patrick F. Kiser
Int J Pharm. Author manuscript; available in PMC 2012 July 15.
Published in final edited form as: Int J Pharm. 2011 July 15; 413(1-2): 10–18. Published online 2011 April 12. doi: 10.1016/j.ijpharm.2011.04.004
PMCID:
PMC3109121
Free in PMC on 2012/07/15
Virucidal Activity of the Dendrimer Microbicide SPL7013 Against HIV-1
Sushama Telwatte, Katie Moore, Adam Johnson, David Tyssen, Jasminka Sterjovski, Muriel Aldunate, Paul R Gorry, Paul A Ramsland, Gareth R Lewis, Jeremy R A Paull, Secondo Sonza, Gilda Tachedjian
Antiviral Res. Author manuscript; available in PMC 2012 June 1.
Published in final edited form as: Antiviral Res. 2011 June; 90(3): 195–199. Published online 2011 April 1. doi: 10.1016/j.antiviral.2011.03.186
PMCID:
PMC3115201
Free in PMC on 2012/06/01
Mucosal Human Defensins 5 and 6 Antagonize the Anti-HIV Activity of Candidate Polyanion Microbicides
Jian Ding, Aprille Rapista, Natalia Teleshova, Wuyuan Lu, Mary E. Klotman, Theresa L. Chang
J Innate Immun. 2011 February; 3(2): 208–212. Published online 2010 December 16. doi: 10.1159/000322355
PMCID:
PMC3072205
Abstract Full Text PDF–117K
Requirements for Receptor Engagement during Infection by Adenovirus Complexed with Blood Coagulation Factor X
Angela C. Bradshaw, Alan L. Parker, Margaret R. Duffy, Lynda Coughlan, Nico van Rooijen, Veli-Matti Kähäri, Stuart A. Nicklin, Andrew H. Baker
PLoS Pathog. 2010 October; 6(10): e1001142. Published online 2010 October 7. doi: 10.1371/journal.ppat.1001142
PMCID:
PMC2951380
Abstract Full Text PDF–11M Supplementary Material
In Vitro Evaluation of Viability, Integrity, and Inflammation in Genital Epithelia upon Exposure to Pharmaceutical Excipients and Candidate Microbicides
Youssef Gali, Olivier Delezay, Joachim Brouwers, Noura Addad, Patrick Augustijns, Thomas Bourlet, Hind Hamzeh-Cognasse, Kevin K. Ariën, Bruno Pozzetto, Guido Vanham
Antimicrob Agents Chemother. 2010 December; 54(12): 5105–5114. Published online 2010 October 4. doi: 10.1128/AAC.00456-10
PMCID:
PMC2981258
Abstract Full Text PDF–1.0M
Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity
David Tyssen, Scott A. Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Jennifer La, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P. Giannis, Guy Krippner, Steve Wesselingh, Tom McCarthy, Paul R. Gorry, Paul A. Ramsland, Richard Cone, Jeremy R. A. Paull, Gareth R. Lewis, Gilda Tachedjian
PLoS One. 2010; 5(8): e12309. Published online 2010 August 23. doi: 10.1371/journal.pone.0012309
PMCID:
PMC2925893
Abstract Full Text PDF–1.0M Supplementary Material
Ex Vivo Comparison of Microbicide Efficacies for Preventing HIV-1 Genomic Integration in Intraepithelial Vaginal Cells
M. Juliana McElrath, Lamar Ballweber, Andrew Terker, Allison Kreger, Polachai Sakchalathorn, Barry Robinson, Michael Fialkow, Gretchen Lentz, Florian Hladik
Antimicrob Agents Chemother. 2010 February; 54(2): 763–772. Published online 2009 November 30. doi: 10.1128/AAC.00891-09
PMCID:
PMC2812173
Abstract Full Text PDF–2.5M Supplementary Material
Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells
Ana Ceballos, Federico Remes Lenicov, Juan Sabatté, Christian Rodríguez Rodrígues, Mercedes Cabrini, Carolina Jancic, Silvina Raiden, Mónica Donaldson, Rodolfo Agustín Pasqualini, Jr., Clara Marin-Briggiler, Mónica Vazquez-Levin, Francisco Capani, Sebastián Amigorena, Jorge Geffner
J Exp Med. 2009 November 23; 206(12): 2717–2733. doi: 10.1084/jem.20091579
PMCID:
PMC2806607
Abstract Full Text PDF–4.1M Supplementary Material
Development of Topical Microbicides to Prevent the Sexual Transmission of HIV
Robert W. Buckheit, Jr., Karen M. Watson, Kathleen M. Morrow, Anthony S. Ham
Antiviral Res. Author manuscript; available in PMC 2011 January 1.
Published in final edited form as: Antiviral Res. 2010 January; 85(1): 142. Published online 2009 October 27. doi: 10.1016/j.antiviral.2009.10.013
PMCID:
PMC2815091
Abstract Full Text PDF–1.4M
Multisite Comparison of Anti-Human Immunodeficiency Virus Microbicide Activity in Explant Assays Using a Novel Endpoint Analysis
Nicola Richardson-Harman, Carol Lackman-Smith, Patricia S. Fletcher, Peter A. Anton, James W. Bremer, Charlene S. Dezzutti, Julie Elliott, Jean-Charles Grivel, Patricia Guenthner, Phalguni Gupta, Maureen Jones, Nell S. Lurain, Leonid B. Margolis, Swarna Mohan, Deena Ratner, Patricia Reichelderfer, Paula Roberts, Robin J. Shattock, James E. Cummins, Jr.
J Clin Microbiol. 2009 November; 47(11): 3530–3539. Published online 2009 September 2. doi: 10.1128/JCM.00673-09
PMCID:
PMC2772583
Abstract Full Text PDF–830K Supplementary Material
Human Immunodeficiency Virus Type 1 Nucleocapsid Inhibitors Impede trans Infection in Cellular and Explant Models and Protect Nonhuman Primates from Infection
Gregory S. Wallace, Cecilia Cheng-Mayer, Marco L. Schito, Patricia Fletcher, Lisa M. Miller Jenkins, Ryo Hayashi, A. Robert Neurath, Ettore Appella, Robin J. Shattock
J Virol. 2009 September; 83(18): 9175–9182. Published online 2009 July 8. doi: 10.1128/JVI.00820-09
PMCID:
PMC2738238
Abstract Full Text PDF–857K Supplementary Material
Enhancement of Human Immunodeficiency Virus Type 1 Replication Is Not Intrinsic to All Polyanion-Based Microbicides
Secondo Sonza, Adam Johnson, David Tyssen, Tim Spelman, Gareth R. Lewis, Jeremy R. A. Paull, Gilda Tachedjian
Antimicrob Agents Chemother. 2009 August; 53(8): 3565–3568. Published online 2009 June 15. doi: 10.1128/AAC.00102-09
PMCID:
PMC2715623
Abstract Full Text PDF–487K
The Differential Binding and Activity of PRO 2000 Against Diverse HIV-1 Envelopes
Darpun D. Sachdev, Bouchra Zerhouni-Layachi, Mila Ortigoza, Albert T. Profy, Michael Tuen, Catarina E. Hioe, Mary E. Klotman
J Acquir Immune Defic Syndr. Author manuscript; available in PMC 2010 June 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2009 June 1; 51(2): 125–129. doi: 10.1097/QAI.0b013e31819f9e31
PMCID:
PMC2718789
Abstract Full Text PDF–336K
Packaging Limits and Stability of HIV-1 Sequences in a Coxsackievirus B Vector
John P. Miller, Yongzhi Geng, Hwee L. Ng, Otto O. Yang, Paul Krogstad
Vaccine. Author manuscript; available in PMC 2010 June 19.
Published in final edited form as: Vaccine. 2009 June 19; 27(30): 3992–4000. Published online 2009 May 3. doi: 10.1016/j.vaccine.2009.04.035
PMCID:
PMC2745320
Abstract Full Text PDF–1.1M
Inhibition of Human Immunodeficiency Virus Type 1 Infection by the Candidate Microbicide Dapivirine, a Nonnucleoside Reverse Transcriptase Inhibitor
P. Fletcher, S. Harman, H. Azijn, N. Armanasco, P. Manlow, D. Perumal, M.-P. de Bethune, J. Nuttall, J. Romano, R. Shattock
Antimicrob Agents Chemother. 2009 February; 53(2): 487–495. Published online 2008 November 24. doi: 10.1128/AAC.01156-08
PMCID:
PMC2630639
Abstract Full Text PDF–560K
Short Communication: Enhancement of HIV Infection by Cellulose Sulfate
Wang Tao, Chris Richards, Dean Hamer
AIDS Res Hum Retroviruses. 2008 July; 24(7): 925–929. doi: 10.1089/aid.2008.0043
PMCID:
PMC2927036
Abstract Full Text PDF–110K
Inhibitory Effect of PRO 2000, a Candidate Microbicide, on Dendritic Cell-Mediated Human Immunodeficiency Virus Transfer
Natalia Teleshova, Theresa Chang, Albert Profy, Mary E. Klotman
Antimicrob Agents Chemother. 2008 May; 52(5): 1751–1758. Published online 2008 March 10. doi: 10.1128/AAC.00707-07
PMCID:
PMC2346652
Abstract Full Text PDF–762K
Preclinical evaluation of lime juice as a topical microbicide candidate
Patricia S Fletcher, Sarah J Harman, Adrienne R Boothe, Gustavo F Doncel, Robin J Shattock
Retrovirology. 2008; 5: 3. Published online 2008 January 11. doi: 10.1186/1742-4690-5-3
PMCID:
PMC2259360
Abstract Full Text PDF–643K
HUMAN CYTOMEGALOVIRUS AND HUMAN IMMUNODEFICIENCY VIRUS TYPE-1 CO-INFECTION IN HUMAN CERVICAL TISSUE
Andrea M. Fox-Canale, Thomas J. Hope, Jeffrey Martinson, John R. Lurain, Alfred W. Rademaker, JamesW. Bremer, Alan Landay, Gregory T. Spear, Nell S. Lurain
Virology. Author manuscript; available in PMC 2008 December 5.
Published in final edited form as: Virology. 2007 December 5; 369(1): 55–68. Published online 2007 August 22. doi: 10.1016/j.virol.2007.07.008
PMCID:
PMC2174066
Abstract Full Text PDF–1.2M
Role of seminal plasma in the anti-HIV-1 activity of candidate microbicides
A Robert Neurath, Nathan Strick, Yun-Yao Li
BMC Infect Dis. 2006; 6: 150. Published online 2006 October 16. doi: 10.1186/1471-2334-6-150
PMCID:
PMC1618840
Abstract Full Text PDF–321K
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