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Journal List > Calif Med > v.90(1); Jan 1959

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Calif Med. 1959 January; 90(1): 26–28.
PMCID: PMC1577532
Copyright notice
USE OF METHOCARBAMOL IN ORTHOPEDICS
William B. Lewis
Abstract
A new skeletal muscle relaxant, methocarbamol, was used in the treatment of 38 patients with a variety of severe neurological disorders and skeletal muscle spasm states.
Eighty-two per cent of the patients studied obtained a beneficial result ranging from excellent to fair.
Mild side effects such as drowsiness were observed in five patients, mild weakness in three patients and excessive perspiration in one. In two of the five patients who complained of drowsiness, it disappeared upon reduction of dosage and did not reappear when original dosage was reinstituted.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • CARPENTER EB. Methocarbamol as a muscle relaxant: its clinical evaluation in acute trauma and chronic neurological states. South Med J. 1958 May;51(5):627–630. [PubMed]
  • FORSYTH HF. Methocarbamol (robaxin) in orthopedic conditions; preliminary report of one hundred cases. J Am Med Assoc. 1958 May 10;167(2):163–168. [PubMed]
  • GIBSON JW, BLUESTONE SS, LOWMAN EW. Zoxazolamine and/or chlorpromazine for muscle spasm. J Am Med Assoc. 1957 Sep 7;165(1):18–20. [PubMed]
  • GINZEL KH. Vergleichende Untersuchung einiger antikonvulsiv wirksamer Glyzerinäther. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1951;212(3-4):330–338. [PubMed]
  • MORGAN AM, TRUITT EH, Jr, LITTLE JM. Plasma levels of mephenesin, mephenesin carbamate, guaiacol glyceryl ether, and methocarbamol (AHR-85) after oral and intravenous administration in the dog. J Am Pharm Assoc Am Pharm Assoc (Baltim). 1957 Jun;46(6):374–377. [PubMed]
  • PARK HW. Clinical results with methocarbamol, a new interneuronal blocking agent. J Am Med Assoc. 1958 May 10;167(2):168–172. [PubMed]
  • RODRIGUEZ-GOMEZ M, VALDES-RODRIGUEZ A, DREW AL. Effect of zoxazolamine (flexin) in treatment of spasticity; preliminary report. J Am Med Assoc. 1956 Mar 3;160(9):752–754. [PubMed]
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