Figure 4
Plasma cholesterol levels in the Gulo mutant males (A) and
females (B). Mean ± SEM. Homozygotes (−/−) were on chow with vitamin C supplement until 3–5 weeks before the determinations. Heterozygotes andwild-type mice were on unsupplemented chow at all times. Correlation between plasma ascorbic acid (AA) andplasma total cholesterol (C) andHDL cholesterol (D) levels in individual animals including all three genotypes. Some homozygotes were with vitamin C supplement andothers were unsupplemented. ○, females; ■, males.
females (B). Mean ± SEM. Homozygotes (−/−) were on chow with vitamin C supplement until 3–5 weeks before the determinations. Heterozygotes andwild-type mice were on unsupplemented chow at all times. Correlation between plasma ascorbic acid (AA) andplasma total cholesterol (C) andHDL cholesterol (D) levels in individual animals including all three genotypes. Some homozygotes were with vitamin C supplement andothers were unsupplemented. ○, females; ■, males.