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The amyloid precursor protein: beyond amyloid
Hui Zheng, Edward H Koo
Mol Neurodegener. 2006; 1: 5. Published online 2006 July 3. doi: 10.1186/1750-1326-1-5
PMCID:
PMC1538601
Abstract Full Text PDF–519K

Is Cited by the Following 42 Articles in this Archive:

Knockdown of Amyloid Precursor Protein in Zebrafish Causes Defects in Motor Axon Outgrowth
Ping Song, Sanjay W. Pimplikar
PLoS One. 2012; 7(4): e34209. Published online 2012 April 24. doi: 10.1371/journal.pone.0034209
PMCID:
PMC3335837
Abstract Full Text PDF–779K Supplementary Material
Physiological Functions of APP Family Proteins
Ulrike C. Müller, Hui Zheng
Cold Spring Harb Perspect Med. 2012 February; 2(2): a006288. doi: 10.1101/cshperspect.a006288
PMCID:
PMC3281588
Abstract Full Text PDF–733K
Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells
Lin Zheng, Alexei Terman, Martin Hallbeck, Nodi Dehvari, Richard F. Cowburn, Eirikur Benedikz, Katarina Kågedal, Angel Cedazo-Minguez, Jan Marcusson
Autophagy. 2011 December 1; 7(12): 1528–1545. doi: 10.4161/auto.7.12.18051
PMCID:
PMC3288025
Free in PMC on 2012/12/01
APP physiological and pathophysiological functions: insights from animal models
Qinxi Guo, Zilai Wang, Hongmei Li, Mary Wiese, Hui Zheng
Cell Res. 2012 January; 22(1): 78–89. Published online 2011 July 19. doi: 10.1038/cr.2011.116
PMCID:
PMC3351924
Free in PMC on 2013/01/01
Alzheimer’s Disease
Dennis J. Selkoe
Cold Spring Harb Perspect Biol. 2011 July; 3(7): a004457. doi: 10.1101/cshperspect.a004457
PMCID:
PMC3119915
Free in PMC on 2013/07/01
Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling
Xuan Xu, Haiying Zhou, Thomas G Boyer
EMBO Rep. 2011 March 3; 12(3): 216–222. Published online 2011 February 4. doi: 10.1038/embor.2010.210
PMCID:
PMC3059912
Abstract Full Text PDF–758K Supplementary Material
Evidence from Solid-State NMR for Nonhelical Conformations in the Transmembrane Domain of the Amyloid Precursor Protein
Jun-Xia Lu, Wai-Ming Yau, Robert Tycko
Biophys J. 2011 February 2; 100(3): 711–719. doi: 10.1016/j.bpj.2010.12.3696
PMCID:
PMC3030151
Abstract Full Text PDF–359K Supplementary Material
APP processing in Alzheimer's disease
Yun-wu Zhang, Robert Thompson, Han Zhang, Huaxi Xu
Mol Brain. 2011; 4: 3. Published online 2011 January 7. doi: 10.1186/1756-6606-4-3
PMCID:
PMC3022812
Abstract Full Text PDF–561K
Cellular basis of Alzheimer’s disease
Jitin Bali, Saoussen Ben Halima, Boas Felmy, Zoe Goodger, Sebastian Zurbriggen, Lawrence Rajendran
Ann Indian Acad Neurol. 2010 December; 13(Suppl2): S89–S93. doi: 10.4103/0972-2327.74251
PMCID:
PMC3039159
Abstract Full Text
Tyr682 in the Intracellular Domain of APP Regulates Amyloidogenic APP Processing In Vivo
Alessia P. M. Barbagallo, Richard Weldon, Robert Tamayev, Dawang Zhou, Luca Giliberto, Oded Foreman, Luciano D'Adamio
PLoS One. 2010; 5(11): e15503. Published online 2010 November 16. doi: 10.1371/journal.pone.0015503
PMCID:
PMC2982846
Abstract Full Text PDF–746K
Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model
Xu Wang, Wei Zheng, Jing-Wei Xie, Tao Wang, Si-Ling Wang, Wei-Ping Teng, Zhan-You Wang
Mol Neurodegener. 2010; 5: 46. Published online 2010 November 2. doi: 10.1186/1750-1326-5-46
PMCID:
PMC2987993
Abstract Full Text PDF–4.8M
Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans
Mary Wiese, Adam Antebi, Hui Zheng
PLoS One. 2010; 5(9): e12790. Published online 2010 September 20. doi: 10.1371/journal.pone.0012790
PMCID:
PMC2942829
Abstract Full Text PDF–1.9M Supplementary Material
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
Hongmei Li, Baiping Wang, Zilai Wang, Qinxi Guo, Katsuhiko Tabuchi, Robert E. Hammer, Thomas C. Südhof, Hui Zheng
Proc Natl Acad Sci U S A. 2010 October 5; 107(40): 17362–17367. Published online 2010 September 20. doi: 10.1073/pnas.1012568107
PMCID:
PMC2951422
Abstract Full Text PDF–1022K Supplementary Material
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
Hongmei Li, Zilai Wang, Baiping Wang, Qinxi Guo, Georgia Dolios, Katsuhiko Tabuchi, Robert E. Hammer, Thomas C. Südhof, Rong Wang, Hui Zheng
J Biol Chem. 2010 October 1; 285(40): 30598–30605. Published online 2010 August 6. doi: 10.1074/jbc.M110.137729
PMCID:
PMC2945554
Abstract Full Text
Aging and excitotoxic stress exacerbate neural circuit reorganization in APP intracellular domain (AICD) transgenic mice
Kaushik Ghosal, Sanjay W. Pimplikar
Neurobiol Aging. Author manuscript; available in PMC 2012 December 1.
Published in final edited form as: Neurobiol Aging. 2011 December; 32(12): 2320.e1–2320.e9. Published online 2010 May 20. doi: 10.1016/j.neurobiolaging.2010.04.020
PMCID:
PMC2928862
Free in PMC on 2012/12/01
Dose-Responsive Gene Expression Changes in Juvenile and Adult Mummichogs (Fundulus heteroclitus) After Arsenic Exposure
Horacio O. Gonzalez, Jianjun Hu, Kristen M. Gaworecki, Jonathan A. Roling, William S. Baldwin, Jorge L. Gardea-Torresdey, Lisa J. Bain
Mar Environ Res. Author manuscript; available in PMC 2011 August 1.
Published in final edited form as: Mar Environ Res. 2010 August; 70(2): 133–141. Published online 2010 April 24. doi: 10.1016/j.marenvres.2010.04.003
PMCID:
PMC2900493
Abstract Full Text PDF–633K
Histone Deacetylase Inhibitor Valproic Acid Inhibits Cancer Cell Proliferation via Down-regulation of the Alzheimer Amyloid Precursor Protein
Vivek Venkataramani, Christian Rossner, Lara Iffland, Stefan Schweyer, Irfan Y. Tamboli, Jochen Walter, Oliver Wirths, Thomas A. Bayer
J Biol Chem. 2010 April 2; 285(14): 10678–10689. Published online 2010 February 9. doi: 10.1074/jbc.M109.057836
PMCID:
PMC2856276
Abstract Full Text Supplementary Material
Transgenic Mouse Models of Alzheimer’s Disease
Gregory A. Elder, Miguel A. Gama Sosa, Rita De Gasperi
Mt Sinai J Med. Author manuscript; available in PMC 2010 August 23.
Published in final edited form as: Mt Sinai J Med. 2010 January; 77(1): 69–81. doi: 10.1002/msj.20159
PMCID:
PMC2925685
Abstract Full Text PDF–94K
Amyloid Precursor Protein Regulates Cav1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-term Plasticity
Li Yang, Zilai Wang, Baiping Wang, Nicholas J. Justice, Hui Zheng
J Neurosci. Author manuscript; available in PMC 2010 June 16.
Published in final edited form as: J Neurosci. 2009 December 16; 29(50): 15660–15668. doi: 10.1523/JNEUROSCI.4104-09.2009
PMCID:
PMC2833283
Abstract Full Text PDF–1.4M Supplementary Material
Pharmacology of epigenetics in brain disorders
Pritika Narayan, Mike Dragunow
Br J Pharmacol. 2010 January; 159(2): 285–303. Published online 2009 December 15. doi: 10.1111/j.1476-5381.2009.00526.x
PMCID:
PMC2825351
Abstract Full Text PDF–423K
Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
Kaushik Ghosal, Daniel L. Vogt, Man Liang, Yong Shen, Bruce T. Lamb, Sanjay W. Pimplikar
Proc Natl Acad Sci U S A. 2009 October 27; 106(43): 18367–18372. Published online 2009 October 16. doi: 10.1073/pnas.0907652106
PMCID:
PMC2762847
Abstract Full Text PDF–1.6M Supplementary Material
Receptor-associated Protein Interacts with Amyloid-β Peptide and Promotes Its Cellular Uptake
Takahisa Kanekiyo, Guojun Bu
J Biol Chem. 2009 November 27; 284(48): 33352–33359. Published online 2009 October 13. doi: 10.1074/jbc.M109.015032
PMCID:
PMC2785178
Abstract Full Text Supplementary Material
Mechanism for Amyloid Precursor-like Protein 2 Enhancement of Major Histocompatibility Complex Class I Molecule Degradation
Amit Tuli, Mahak Sharma, Haley L. Capek, Naava Naslavsky, Steve Caplan, Joyce C. Solheim
J Biol Chem. 2009 December 4; 284(49): 34296–34307. Published online 2009 October 6. doi: 10.1074/jbc.M109.039727
PMCID:
PMC2797198
Abstract Full Text Supplementary Material
Alzheimer’s disease as homeostatic responses to age-related myelin breakdown
George Bartzokis
Neurobiol Aging. Author manuscript; available in PMC 2011 August 1.
Published in final edited form as: Neurobiol Aging. 2011 August; 32(8): 1341–1371. Published online 2009 September 22. doi: 10.1016/j.neurobiolaging.2009.08.007
PMCID:
PMC3128664
Abstract Full Text PDF–2.9M
Pre- and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
Zilai Wang, Baiping Wang, Li Yang, Qinxi Guo, Nadia Aithmitti, Zhou Songyang, Hui Zheng
J Neurosci. Author manuscript; available in PMC 2010 March 2.
Published in final edited form as: J Neurosci. 2009 September 2; 29(35): 10788–10801. doi: 10.1523/JNEUROSCI.2132-09.2009
PMCID:
PMC2757256
Abstract Full Text PDF–3.9M Supplementary Material
Intracellular Trafficking of Presenilin 1 Is Regulated by β-Amyloid Precursor Protein and Phospholipase D1
Yun Liu, Yun-wu Zhang, Xin Wang, Han Zhang, Xiaoqing You, Francesca-Fang Liao, Huaxi Xu
J Biol Chem. 2009 May 1; 284(18): 12145–12152. doi: 10.1074/jbc.M808497200
PMCID:
PMC2673283
Abstract Full Text
LRP1 shedding in human brain: roles of ADAM10 and ADAM17
Qiang Liu, Juan Zhang, Hien Tran, Marcel M Verbeek, Karina Reiss, Steven Estus, Guojun Bu
Mol Neurodegener. 2009; 4: 17. Published online 2009 April 16. doi: 10.1186/1750-1326-4-17
PMCID:
PMC2672942
Abstract Full Text PDF–558K
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
Xinglong Wang, Bo Su, Sandra L. Siedlak, Paula I. Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu
Proc Natl Acad Sci U S A. 2008 December 9; 105(49): 19318–19323. Published online 2008 December 2. doi: 10.1073/pnas.0804871105
PMCID:
PMC2614759
Abstract Full Text PDF–791K Supplementary Material
Genetic Dissection of γ-secretase-dependent and - independent Functions of Presenilin in Regulating Neuronal Cell Cycle and Cell Death
Verena Kallhoff-Munoz, Lingyun Hu, Xiaoli Chen, Robia G. Pautler, Hui Zheng
J Neurosci. Author manuscript; available in PMC 2009 April 29.
Published in final edited form as: J Neurosci. 2008 October 29; 28(44): 11421–11431. doi: 10.1523/JNEUROSCI.2873-08.2008
PMCID:
PMC2615184
Abstract Full Text PDF–2.5M Supplementary Material
Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer’s disease
Maria-Paz Marzolo, Guojun Bu
Semin Cell Dev Biol. Author manuscript; available in PMC 2010 April 1.
Published in final edited form as: Semin Cell Dev Biol. 2009 April; 20(2): 191–200. Published online 2008 October 17. doi: 10.1016/j.semcdb.2008.10.005
PMCID:
PMC2691858
Abstract Full Text PDF–660K
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