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Environmental and dietary estrogens and human health: is there a problem?
S H Safe
Environ Health Perspect. 1995 April; 103(4): 346–351.
PMCID: PMC1519094
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 Is Cited by the Following Articles in this Archive:
Maternal Pregnancy Levels of Polychlorinated Biphenyls and Risk of Hypospadias and Cryptorchidism in Male Offspring
Katherine A. McGlynn, Xuguang Guo, Barry I. Graubard, John W. Brock, Mark A. Klebanoff, and Matthew P. Longnecker
Environ Health Perspect. 2009 September; 117(9): 1472–1476. Published online 2009 April 20. doi: 10.1289/ehp.0800389.
PMCID: PMC2737028
Cadmium - a metallohormone?
Celia Byrne, Shailaja D. Divekar, Geoffrey B. Storchan, Daniela A. Parodi, and Mary Beth Martin
Toxicol Appl Pharmacol. Author manuscript; available in PMC 2009 August 1.
PMCID: PMC2709711
Published in final edited form as: Toxicol Appl Pharmacol. 2009 August 1; 238(3): 266–271. Published online 2009 April 9. doi: 10.1016/j.taap.2009.03.025.
Manuscript: | Abstract | Full Text | PDF–199K |
Co-planar 3,3′,4,4′,5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes
Jason Matthews, Björn Wihlén, Nina Heldring, Laura MacPherson, Luisa Helguero, Eckardt Treuter, Lars-Arne Haldosén, and Jan-Åke Gustafsson
Biochem J. 2007 September 1; 406(Pt 2): 343–353. Prepublished online 2007 May 18. Published online 2007 August 13. doi: 10.1042/BJ20070585.
PMCID: PMC1948966
Temporal Changes in Gene Expression in Rainbow Trout Exposed to Ethynyl Estradiol
Sharon E. Hook, Ann D. Skillman, Jack A. Small, and Irvin R. Schultz
Comp Biochem Physiol C Toxicol Pharmacol. Author manuscript; available in PMC 2008 February 1.
PMCID: PMC1885221
Published in final edited form as: Comp Biochem Physiol C Toxicol Pharmacol. 2007 February; 145(1): 73–85. Published online 2006 November 25. doi: 10.1016/j.cbpc.2006.10.011.
Pesticide exposure: the hormonal function of the female reproductive system disrupted?
Reini W Bretveld, Chris MG Thomas, Paul TJ Scheepers, Gerhard A Zielhuis, and Nel Roeleveld
Reprod Biol Endocrinol. 2006; 4: 30. Published online 2006 May 31. doi: 10.1186/1477-7827-4-30.
PMCID: PMC1524969
Assessment of Xenoestrogens Using Three Distinct Estrogen Receptors and the Zebrafish Brain Aromatase Gene in a Highly Responsive Glial Cell System
Yann Le Page, Martin Scholze, Olivier Kah, and Farzad Pakdel
Environ Health Perspect. 2006 May; 114(5): 752–758. Published online 2005 December 8. doi: 10.1289/ehp.8141.
PMCID: PMC1459931
Environmental pollutants and breast cancer.
Julia Green Brody and Ruthann A Rudel
Environ Health Perspect. 2003 June; 111(8): 1007–1019.
PMCID: PMC1241551
Breast cancer and serum organochlorine residues
C Charlier, A Albert, P Herman, E Hamoir, U Gaspard, M Meurisse, and G Plomteux
Occup Environ Med. 2003 May; 60(5): 348–351. doi: 10.1136/oem.60.5.348.
PMCID: PMC1740527
Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: oogenetic, population, and evolutionary implications of endocrine disruption
Augustine Arukwe and Anders Goksøyr
Comp Hepatol. 2003; 2: 4. Published online 2003 March 6. doi: 10.1186/1476-5926-2-4.
PMCID: PMC153486
Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action.
Nissanka Rajapakse, Elisabete Silva, and Andreas Kortenkamp
Environ Health Perspect. 2002 September; 110(9): 917–921.
PMCID: PMC1240992
Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels.
B S Rubin, M K Murray, D A Damassa, J C King, and A M Soto
Environ Health Perspect. 2001 July; 109(7): 675–680.
PMCID: PMC1240370
Modulatory effects of neonatal exposure to TCDD, or a mixture of PCBs, p,p'-DDT, and p-p'-DDE, on methylnitrosourea-induced mammary tumor development in the rat.
D Desaulniers, K Leingartner, J Russo, G Perkins, B G Chittim, M C Archer, M Wade, and J Yang
Environ Health Perspect. 2001 July; 109(7): 739–747.
PMCID: PMC1240379
ARE PROBLEMS WITH MALE REPRODUCTIVE HEALTH CAUSED BY ENDOCRINE DISRUPTION?
M. Joffe
Occup Environ Med. 2001 April; 58(4): 281–288. doi: 10.1136/oem.58.4.281.
PMCID: PMC1740113
Cross-species and interassay comparisons of phytoestrogen action.
P L Whitten and H B Patisaul
Environ Health Perspect. 2001 March; 109(Suppl 1): 5–20.
PMCID: PMC1240538
Estrogenic activity assessment of environmental chemicals using in vitro assays: identification of two new estrogenic compounds.
I Lascombe, D Beffa, U Rüegg, J Tarradellas, and W Wahli
Environ Health Perspect. 2000 July; 108(7): 621–629.
PMCID: PMC1638169
Endocrine disruptors and human health--is there a problem? An update.
S H Safe
Environ Health Perspect. 2000 June; 108(6): 487–493.
PMCID: PMC1638151
Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men.
S Telisman, P Cvitković, J Jurasović, A Pizent, M Gavella, and B Rocić
Environ Health Perspect. 2000 January; 108(1): 45–53.
PMCID: PMC1637869
Anaerobic Dehalogenation of Hydroxylated Polychlorinated Biphenyls by Desulfitobacterium dehalogenans
Juergen Wiegel, Xiaoming Zhang, and Qingzhong Wu
Appl Environ Microbiol. 1999 May; 65(5): 2217–2221.
PMCID: PMC91319
Developmental synergism of steroidal estrogens in sex determination.
J M Bergeron, E Willingham, C T Osborn, 3rd, T Rhen, and D Crews
Environ Health Perspect. 1999 February; 107(2): 93–97.
PMCID: PMC1566333
Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food.
K Gaido, L Dohme, F Wang, I Chen, B Blankvoort, K Ramamoorthy, and S Safe
Environ Health Perspect. 1998 December; 106(Suppl 6): 1347–1351.
PMCID: PMC1533429
Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach.
S H Safe
Environ Health Perspect. 1998 August; 106(Suppl 4): 1051–1058.
PMCID: PMC1533329
Breast cancer in Norway 1970-1993: a population-based study on incidence, mortality and survival.
H. Wang, S. O. Thoresen, and S. Tretli
Br J Cancer. 1998 May; 77(9): 1519–1524.
PMCID: PMC2150186
Identification and assessment of endocrine disruptors: limitations of in vivo and in vitro assays.
T Zacharewski
Environ Health Perspect. 1998 April; 106(Suppl 2): 577–582.
PMCID: PMC1533380
Environmental endocrine disruption: an effects assessment and analysis.
T M Crisp, E D Clegg, R L Cooper, W P Wood, D G Anderson, K P Baetcke, J L Hoffmann, M S Morrow, D J Rodier, J E Schaeffer, L W Touart, M G Zeeman, and Y M Patel
Environ Health Perspect. 1998 February; 106(Suppl 1): 11–56.
PMCID: PMC1533291
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
Barry D. Gehm, Joanne M. McAndrews, Pei-Yu Chien, and J. Larry Jameson
Proc Natl Acad Sci U S A. 1997 December 9; 94(25): 14138–14143.
PMCID: PMC28446
Estrogenic responses in estrogen receptor-α deficient mice reveal a distinct estrogen signaling pathway
S. K. Das, Julia A. Taylor, Kenneth S. Korach, B. C. Paria, S. K. Dey, and Dennis B. Lubahn
Proc Natl Acad Sci U S A. 1997 November 25; 94(24): 12786–12791.
PMCID: PMC24216
Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155).
M R Fielden, I Chen, B Chittim, S H Safe, and T R Zacharewski
Environ Health Perspect. 1997 November; 105(11): 1238–1248.
PMCID: PMC1470342
Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture.
D T Zava, M Blen, and G Duwe
Environ Health Perspect. 1997 April; 105(Suppl 3): 637–645.
PMCID: PMC1469890
Developing a marker of exposure to xenoestrogen mixtures in human serum.
A M Soto, M F Fernandez, M F Luizzi, A S Oles Karasko, and C Sonnenschein
Environ Health Perspect. 1997 April; 105(Suppl 3): 647–654.
PMCID: PMC1469891
Breast cancer and pesticides in Hawaii: the need for further study.
R H Allen, M Gottlieb, E Clute, M J Pongsiri, J Sherman, and G I Obrams
Environ Health Perspect. 1997 April; 105(Suppl 3): 679–683.
PMCID: PMC1469894
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