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Am J Public Health. 1998 June; 88(6): 893–896.
PMCID: PMC1508233

Exposure of young infants to environmental tobacco smoke: breast-feeding among smoking mothers.

Abstract

OBJECTIVES: This study examined the degree to which breast-feeding and cigarette smoking by mothers and smoking by other household members contribute to the exposure of infants to the products of tobacco smoke. METHODS: The subjects were 330 mother-infant pairs derived from a cohort of 1000 pairs enrolled in a longitudinal study of the pulmonary effects of prenatal and postnatal smoking. The main outcome measure was corrected urinary cotinine levels. RESULTS: Urinary cotinine levels were 10-fold higher in breast-fed infants of smoking mothers than among bottle-fed infants of smoking mothers. Among infants of nonsmoking mothers, urine cotinine levels were significantly increased in infants living in homes with other smokers; in this group there was no significant difference between bottle-fed and breast-fed infants. Infants whose mothers smoked in the same room as the infant had only nonsignificant increases in cotinine levels compared with infants whose mothers restricted their smoking to other rooms. CONCLUSIONS: Breast-fed infants of smoking mothers have urine cotinine levels 10-fold higher than bottle-fed infants whose mothers smoke, suggesting that breast-feeding, rather than direct inhalation of environmental tobacco smoke, is the primary determinant of cotinine levels in infants whose mothers smoke.

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Selected References

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  • Weitzman M, Gortmaker S, Walker DK, Sobol A. Maternal smoking and childhood asthma. Pediatrics. 1990 Apr;85(4):505–511. [PubMed]
  • Martinez FD, Cline M, Burrows B. Increased incidence of asthma in children of smoking mothers. Pediatrics. 1992 Jan;89(1):21–26. [PubMed]
  • Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med. 1995 Jan 19;332(3):133–138. [PubMed]
  • Haglund B, Cnattingius S. Cigarette smoking as a risk factor for sudden infant death syndrome: a population-based study. Am J Public Health. 1990 Jan;80(1):29–32. [PMC free article] [PubMed]
  • Schoendorf KC, Kiely JL. Relationship of sudden infant death syndrome to maternal smoking during and after pregnancy. Pediatrics. 1992 Dec;90(6):905–908. [PubMed]
  • Perlman HH, Dannenberg AM, Sokoloff N. The excretion of nicotine in breast milk and urine from cigarette smoking: its effect on lactation and the nursing. J Am Med Assoc. 1942 Nov 28;120(13):1003–1009. [PubMed]
  • Dahlström A, Lundell B, Curvall M, Thapper L. Nicotine and cotinine concentrations in the nursing mother and her infant. Acta Paediatr Scand. 1990 Feb;79(2):142–147. [PubMed]
  • Luck W, Nau H. Nicotine and cotinine concentrations in serum and milk of nursing smokers. Br J Clin Pharmacol. 1984 Jul;18(1):9–15. [PMC free article] [PubMed]
  • Schwartz-Bickenbach D, Schulte-Hobein B, Abt S, Plum C, Nau H. Smoking and passive smoking during pregnancy and early infancy: effects on birth weight, lactation period, and cotinine concentrations in mother's milk and infant's urine. Toxicol Lett. 1987 Jan;35(1):73–81. [PubMed]
  • Luck W, Nau H. Nicotine and cotinine concentrations in serum and urine of infants exposed via passive smoking or milk from smoking mothers. J Pediatr. 1985 Nov;107(5):816–820. [PubMed]
  • Schulte-Hobein B, Schwartz-Bickenbach D, Abt S, Plum C, Nau H. Cigarette smoke exposure and development of infants throughout the first year of life: influence of passive smoking and nursing on cotinine levels in breast milk and infant's urine. Acta Paediatr. 1992 Jun-Jul;81(6-7):550–557. [PubMed]
  • Chilmonczyk BA, Knight GJ, Palomaki GE, Pulkkinen AJ, Williams J, Haddow JE. Environmental tobacco smoke exposure during infancy. Am J Public Health. 1990 Oct;80(10):1205–1208. [PMC free article] [PubMed]
  • Woodward A, Grgurinovich N, Ryan P. Breast feeding and smoking hygiene: major influences on cotinine in urine of smokers' infants. J Epidemiol Community Health. 1986 Dec;40(4):309–315. [PMC free article] [PubMed]
  • Labrecque M, Marcoux S, Weber JP, Fabia J, Ferron L. Feeding and urine cotinine values in babies whose mothers smoke. Pediatrics. 1989 Jan;83(1):93–97. [PubMed]
  • Greenberg RA, Haley NJ, Etzel RA, Loda FA. Measuring the exposure of infants to tobacco smoke. Nicotine and cotinine in urine and saliva. N Engl J Med. 1984 Apr 26;310(17):1075–1078. [PubMed]
  • Langone JJ, Van Vunakis H. Radioimmunoassay of nicotine, cotinine, and gamma-(3-pyridyl)-gamma-oxo-N-methylbutyramide. Methods Enzymol. 1982;84:628–640. [PubMed]

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