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Br Med J (Clin Res Ed). 1982 November 6; 285(6351): 1304–1306. | PMCID: PMC1500200 |
Haemolytic uraemic syndrome: therapeutic effect of plasma infusion. R Misiani, A C Appiani, A Edefonti, E Gotti, A Bettinelli, M Giani, E Rossi, G Remuzzi, and G Mecca Abstract The therapeutic effect of plasma infusion was evaluated in 10 children and seven adults with haemolytic uraemic syndrome. All but one patient responded to this treatment with rapid disappearance of haematological abnormalities. The patient who apparently failed to respond to plasma infusion obtained complete remission of the disease after plasmapheresis. Although 15 of the 17 patients were anuric or oliguric on admission, renal function recovered completely in eight children and two adults. Seven patients showed residual chronic renal failure and two required long-term maintenance haemodialysis. Treatment with plasma was also successful in patients with relapses or recurrent episodes. Plasma infusion is a promising therapeutic approach for the haemolytic uraemic syndrome and deserves further study in clinical trials. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (669K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - Habib R, Mathieu H, Royer P. Le syndrome hémolytique et urémique de l'enfant,. Aspects cliniques et anatomiques dans 27 observations. Nephron. 1967;4(3):139–172. [PubMed]
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