• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of narLink to Publisher's site
Nucleic Acids Res. Jan 1, 1998; 26(1): 1–7.
PMCID: PMC147205

GenBank.

Abstract

The GenBank(R) sequence database (http://www.ncbi.nlm.nih.gov/) incorporates DNA sequences from all available public sources, primarily through the direct submission of sequence data from individual laboratories and from large-scale sequencing projects. Most submitters use the BankIt (WWW) or Sequin programs to send their sequence data. Data exchange with the EMBL Data Library and the DNA Data Bank of Japan helps ensure comprehensive worldwide coverage. GenBank data is accessible through NCBI's integrated retrieval system, Entrez , which integrates data from the major DNA and protein sequence databases along with taxonomy, genome and protein structure information. MEDLINE(R) abstracts from published articles describing the sequences are also included as an additional source of biological annotation. Sequence similarity searching is offered through the BLAST series of database search programs. In addition to FTP, e-mail and server/client versions of Entrez and BLAST, NCBI offers a wide range of World Wide Web retrieval and analysis services of interest to biologists.

Full Text

The Full Text of this article is available as a PDF (234K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Benson DA, Boguski MS, Lipman DJ, Ostell J. GenBank. Nucleic Acids Res. 1997 Jan 1;25(1):1–6. [PMC free article] [PubMed]
  • Aaronson JS, Eckman B, Blevins RA, Borkowski JA, Myerson J, Imran S, Elliston KO. Toward the development of a gene index to the human genome: an assessment of the nature of high-throughput EST sequence data. Genome Res. 1996 Sep;6(9):829–845. [PubMed]
  • Hillier LD, Lennon G, Becker M, Bonaldo MF, Chiapelli B, Chissoe S, Dietrich N, DuBuque T, Favello A, Gish W, et al. Generation and analysis of 280,000 human expressed sequence tags. Genome Res. 1996 Sep;6(9):807–828. [PubMed]
  • Ouellette BF, Boguski MS. Database divisions and homology search files: a guide for the perplexed. Genome Res. 1997 Oct;7(10):952–955. [PubMed]
  • Schuler GD, Boguski MS, Stewart EA, Stein LD, Gyapay G, Rice K, White RE, Rodriguez-Tomé P, Aggarwal A, Bajorek E, et al. A gene map of the human genome. Science. 1996 Oct 25;274(5287):540–546. [PubMed]
  • Hudson TJ, Stein LD, Gerety SS, Ma J, Castle AB, Silva J, Slonim DK, Baptista R, Kruglyak L, Xu SH, et al. An STS-based map of the human genome. Science. 1995 Dec 22;270(5244):1945–1954. [PubMed]
  • Zhang J, Madden TL. PowerBLAST: a new network BLAST application for interactive or automated sequence analysis and annotation. Genome Res. 1997 Jun;7(6):649–656. [PMC free article] [PubMed]
  • Hogue CW, Ohkawa H, Bryant SH. A dynamic look at structures: WWW-Entrez and the Molecular Modeling Database. Trends Biochem Sci. 1996 Jun;21(6):226–229. [PubMed]
  • Hogue CW. Cn3D: a new generation of three-dimensional molecular structure viewer. Trends Biochem Sci. 1997 Aug;22(8):314–316. [PubMed]
  • Gibrat JF, Madej T, Bryant SH. Surprising similarities in structure comparison. Curr Opin Struct Biol. 1996 Jun;6(3):377–385. [PubMed]
  • Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997 Sep 1;25(17):3389–3402. [PMC free article] [PubMed]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • Compound
    Compound
    PubChem Compound links
  • PubMed
    PubMed
    PubMed citations for these articles
  • Substance
    Substance
    PubChem Substance links

Recent Activity

  • GenBank.
    GenBank.
    Nucleic Acids Research. Jan 1, 1998; 26(1)1
    PMC

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...