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Genetics. Feb 2000; 154(2): 857–867.
PMCID: PMC1460941

A genetic map of tomato based on BC(1) Lycopersicon esculentum x Solanum lycopersicoides reveals overall synteny but suppressed recombination between these homeologous genomes.


F(1) hybrids between the cultivated tomato (Lycopersicon esculentum) and the wild nightshade Solanum lycopersicoides are male sterile and unilaterally incompatible, breeding barriers that impede further crosses to tomato. Meiosis is disrupted in 2x hybrids, with reduced chiasma formation and frequent univalents, but is normal in allotetraploid hybrids, indicating the genomes are homeologous. In this study, a partially male-fertile F(1) was backcrossed to tomato, producing the first BC(1) population suitable for genetic mapping from this cross. BC(1) plants were genotyped at marker loci to study the transmission of wild alleles and to measure rates of homeologous recombination. The pattern of segregation distortion, in favor of homozygotes on chromosomes 2 and 5 and heterozygotes on chromosomes 6 and 9, suggested linkage to a small number of loci under selection on each chromosome. Genome ratios nonetheless fit Mendelian expectations. Resulting genetic maps were essentially colinear with existing tomato maps but showed an overall reduction in recombination of approximately 27%. Recombination suppression was observed for all chromosomes except 9 and 12, affected both proximal and distal regions, and was most severe on chromosome 10 (70% reduction). Recombination between markers on the long arm of this chromosome was completely eliminated, suggesting a lack of colinearity between S. lycopersicoides and L. esculentum homeologues in this region. Results are discussed with respect to phylogenetic relationships between the species and their potential use for studies of homeologous pairing and recombination in a diploid plant genome.

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Selected References

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  • Ahn S, Tanksley SD. Comparative linkage maps of the rice and maize genomes. Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7980–7984. [PMC free article] [PubMed]
  • Ahn S, Anderson JA, Sorrells ME, Tanksley SD. Homoeologous relationships of rice, wheat and maize chromosomes. Mol Gen Genet. 1993 Dec;241(5-6):483–490. [PubMed]
  • Begun DJ, Aquadro CF. Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster. Nature. 1992 Apr 9;356(6369):519–520. [PubMed]
  • Bernacchi D, Tanksley SD. An interspecific backcross of Lycopersicon esculentum x L. hirsutum: linkage analysis and a QTL study of sexual compatibility factors and floral traits. Genetics. 1997 Oct;147(2):861–877. [PMC free article] [PubMed]
  • Menzel MY. Preferential Chromosome Pairing in Allotetraploid Lycopersicon Esculentum-solanum Lycopersicoides. Genetics. 1964 Nov;50(5):855–862. [PMC free article] [PubMed]
  • Paterson AH, DeVerna JW, Lanini B, Tanksley SD. Fine mapping of quantitative trait loci using selected overlapping recombinant chromosomes, in an interspecies cross of tomato. Genetics. 1990 Mar;124(3):735–742. [PMC free article] [PubMed]
  • Paterson AH, Lin YR, Li Z, Schertz KF, Doebley JF, Pinson SR, Liu SC, Stansel JW, Irvine JE. Convergent domestication of cereal crops by independent mutations at corresponding genetic Loci. Science. 1995 Sep 22;269(5231):1714–1718. [PubMed]
  • Paterson AH, Lan TH, Reischmann KP, Chang C, Lin YR, Liu SC, Burow MD, Kowalski SP, Katsar CS, DelMonte TA, et al. Toward a unified genetic map of higher plants, transcending the monocot-dicot divergence. Nat Genet. 1996 Dec;14(4):380–382. [PubMed]
  • Pereira MG, Lee M, Bramel-Cox P, Woodman W, Doebley J, Whitkus R. Construction of an RFLP map in sorghum and comparative mapping in maize. Genome. 1994 Apr;37(2):236–243. [PubMed]
  • Prince JP, Pochard E, Tanksley SD. Construction of a molecular linkage map of pepper and a comparison of synteny with tomato. Genome. 1993 Jun;36(3):404–417. [PubMed]
  • Rick CM. Hybrids Between Lycopersicon Esculentum Mill. And Solanum Lycopersicoides Dun. Proc Natl Acad Sci U S A. 1951 Nov;37(11):741–744. [PMC free article] [PubMed]
  • Faris JD, Laddomada B, Gill BS. Molecular mapping of segregation distortion loci in Aegilops tauschii. Genetics. 1998 May;149(1):319–327. [PMC free article] [PubMed]
  • Rick CM, De Verna JW, Chetelat RT, Stevens MA. Meiosis in sesquidiploid hybrids of Lycopersicon esculentum and Solanum lycopersicoides. Proc Natl Acad Sci U S A. 1986 Jun;83(11):3580–3583. [PMC free article] [PubMed]
  • Sawant AC. Cytogenetics of Interspecific Hybrids, Lycopersicon Esculentum Mill. x L. Hirsutum Humb. and Bonpl. Genetics. 1958 May;43(3):502–514. [PMC free article] [PubMed]
  • Sherman JD, Stack SM. Two-dimensional spreads of synaptonemal complexes from solanaceous plants. VI. High-resolution recombination nodule map for tomato (Lycopersicon esculentum). Genetics. 1995 Oct;141(2):683–708. [PMC free article] [PubMed]
  • Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newberg LA, Newburg L. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics. 1987 Oct;1(2):174–181. [PubMed]
  • Tanksley SD, Ganal MW, Prince JP, de Vicente MC, Bonierbale MW, Broun P, Fulton TM, Giovannoni JJ, Grandillo S, Martin GB, et al. High density molecular linkage maps of the tomato and potato genomes. Genetics. 1992 Dec;132(4):1141–1160. [PMC free article] [PubMed]

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