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Am J Hum Genet. Nov 1998; 63(5): 1271–1276.
PMCID: PMC1377537

6-n-Propylthiouracil: a genetic marker for taste, with implications for food preference and dietary habits.

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Selected References

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  • Anliker JA, Bartoshuk L, Ferris AM, Hooks LD. Children's food preferences and genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP). Am J Clin Nutr. 1991 Aug;54(2):316–320. [PubMed]
  • Bartoshuk LM, Duffy VB, Miller IJ. PTC/PROP tasting: anatomy, psychophysics, and sex effects. Physiol Behav. 1994 Dec;56(6):1165–1171. [PubMed]
  • Drewnowski A, Henderson SA, Barratt-Fornell A. Genetic sensitivity to 6-n-propylthiouracil and sensory responses to sugar and fat mixtures. Physiol Behav. 1998 Mar;63(5):771–777. [PubMed]
  • Drewnowski A, Henderson SA, Shore AB. Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. Am J Clin Nutr. 1997 Aug;66(2):391–397. [PubMed]
  • Drewnowski A, Henderson SA, Shore AB, Barratt-Fornell A. Nontasters, tasters, and supertasters of 6-n-propylthiouracil (PROP) and hedonic response to sweet. Physiol Behav. 1997 Sep;62(3):649–655. [PubMed]
  • Drewnowski A, Rock CL. The influence of genetic taste markers on food acceptance. Am J Clin Nutr. 1995 Sep;62(3):506–511. [PubMed]
  • Drewnowski A, Schwartz M. Invisible fats: sensory assessment of sugar/fat mixtures. Appetite. 1990 Jun;14(3):203–217. [PubMed]
  • Karrer T, Bartoshuk L. Capsaicin desensitization and recovery on the human tongue. Physiol Behav. 1991 Apr;49(4):757–764. [PubMed]
  • Liu L, Simon SA. Similarities and differences in the currents activated by capsaicin, piperine, and zingerone in rat trigeminal ganglion cells. J Neurophysiol. 1996 Sep;76(3):1858–1869. [PubMed]
  • Looy H, Weingarten HP. Facial expressions and genetic sensitivity to 6-n-propylthiouracil predict hedonic response to sweet. Physiol Behav. 1992 Jul;52(1):75–82. [PubMed]
  • Olson JM, Boehnke M, Neiswanger K, Roche AF, Siervogel RM. Alternative genetic models for the inheritance of the phenylthiocarbamide taste deficiency. Genet Epidemiol. 1989;6(3):423–434. [PubMed]
  • Prescott J, Stevenson RJ. Psychophysical responses to single and multiple presentations of the oral irritant zingerone: relationship to frequency of chili consumption. Physiol Behav. 1996 Aug;60(2):617–624. [PubMed]
  • Reddy BM, Rao DC. Phenylthiocarbamide taste sensitivity revisited: complete sorting test supports residual family resemblance. Genet Epidemiol. 1989;6(3):413–421. [PubMed]
  • Reed DR, Bartoshuk LM, Duffy V, Marino S, Price RA. Propylthiouracil tasting: determination of underlying threshold distributions using maximum likelihood. Chem Senses. 1995 Oct;20(5):529–533. [PubMed]
  • Stevenson RJ, Prescott J. The effects of prior experience with capsaicin on ratings of its burn. Chem Senses. 1994 Dec;19(6):651–656. [PubMed]
  • Tepper BJ, Nurse RJ. Fat perception is related to PROP taster status. Physiol Behav. 1997 Jun;61(6):949–954. [PubMed]
  • Whissell-Buechy D, Wills C. Male and female correlations for taster (P.T.C.) phenotypes and rate of adolescent development. Ann Hum Biol. 1989 Mar-Apr;16(2):131–146. [PubMed]

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