Logo of ajhgLink to Publisher's site
Am J Hum Genet. 1998 Nov; 63(5): 1271–1276.
PMCID: PMC1377537

6-n-Propylthiouracil: a genetic marker for taste, with implications for food preference and dietary habits.

Full Text

The Full Text of this article is available as a PDF (293K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Anliker JA, Bartoshuk L, Ferris AM, Hooks LD. Children's food preferences and genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP). Am J Clin Nutr. 1991 Aug;54(2):316–320. [PubMed]
  • Bartoshuk LM, Duffy VB, Miller IJ. PTC/PROP tasting: anatomy, psychophysics, and sex effects. Physiol Behav. 1994 Dec;56(6):1165–1171. [PubMed]
  • Drewnowski A, Henderson SA, Barratt-Fornell A. Genetic sensitivity to 6-n-propylthiouracil and sensory responses to sugar and fat mixtures. Physiol Behav. 1998 Mar;63(5):771–777. [PubMed]
  • Drewnowski A, Henderson SA, Shore AB. Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. Am J Clin Nutr. 1997 Aug;66(2):391–397. [PubMed]
  • Drewnowski A, Henderson SA, Shore AB, Barratt-Fornell A. Nontasters, tasters, and supertasters of 6-n-propylthiouracil (PROP) and hedonic response to sweet. Physiol Behav. 1997 Sep;62(3):649–655. [PubMed]
  • Drewnowski A, Rock CL. The influence of genetic taste markers on food acceptance. Am J Clin Nutr. 1995 Sep;62(3):506–511. [PubMed]
  • Drewnowski A, Schwartz M. Invisible fats: sensory assessment of sugar/fat mixtures. Appetite. 1990 Jun;14(3):203–217. [PubMed]
  • Karrer T, Bartoshuk L. Capsaicin desensitization and recovery on the human tongue. Physiol Behav. 1991 Apr;49(4):757–764. [PubMed]
  • Liu L, Simon SA. Similarities and differences in the currents activated by capsaicin, piperine, and zingerone in rat trigeminal ganglion cells. J Neurophysiol. 1996 Sep;76(3):1858–1869. [PubMed]
  • Looy H, Weingarten HP. Facial expressions and genetic sensitivity to 6-n-propylthiouracil predict hedonic response to sweet. Physiol Behav. 1992 Jul;52(1):75–82. [PubMed]
  • Olson JM, Boehnke M, Neiswanger K, Roche AF, Siervogel RM. Alternative genetic models for the inheritance of the phenylthiocarbamide taste deficiency. Genet Epidemiol. 1989;6(3):423–434. [PubMed]
  • Prescott J, Stevenson RJ. Psychophysical responses to single and multiple presentations of the oral irritant zingerone: relationship to frequency of chili consumption. Physiol Behav. 1996 Aug;60(2):617–624. [PubMed]
  • Reddy BM, Rao DC. Phenylthiocarbamide taste sensitivity revisited: complete sorting test supports residual family resemblance. Genet Epidemiol. 1989;6(3):413–421. [PubMed]
  • Reed DR, Bartoshuk LM, Duffy V, Marino S, Price RA. Propylthiouracil tasting: determination of underlying threshold distributions using maximum likelihood. Chem Senses. 1995 Oct;20(5):529–533. [PubMed]
  • Stevenson RJ, Prescott J. The effects of prior experience with capsaicin on ratings of its burn. Chem Senses. 1994 Dec;19(6):651–656. [PubMed]
  • Tepper BJ, Nurse RJ. Fat perception is related to PROP taster status. Physiol Behav. 1997 Jun;61(6):949–954. [PubMed]
  • Whissell-Buechy D, Wills C. Male and female correlations for taster (P.T.C.) phenotypes and rate of adolescent development. Ann Hum Biol. 1989 Mar-Apr;16(2):131–146. [PubMed]

Articles from American Journal of Human Genetics are provided here courtesy of American Society of Human Genetics


Save items

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


  • Compound
    PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
  • OMIM
    Genome Survey Sequence (GSS) nucleotide records reported in the current articles.
  • PubMed
    PubMed citations for these articles
  • Substance
    PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...