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Ann Surg. 1983 December; 198(6): 701–704. | PMCID: PMC1353217 |
Aminopyrine breath test predicts surgical risk for patients with liver disease. R A Gill, M W Goodman, G R Golfus, G R Onstad, and M P Bubrick Abstract To determine whether the [14C] aminopyrine breath test (ABT) predicts surgical risk in patients with liver disease, it was obtained prior to various surgeries in 38 patients with known or suspected liver disease. A modified Child's classification was also determined. Six of the seven operative deaths (three Child's A, two B, two C) had ABTs less than 2.3%, while 30 of 31 survivors (24 Child's A, seven B) had ABTs greater than 2.3% (p less than 0.000018). Seven of the 16 patients with normal ABTs had biopsy-proven cirrhosis and had postoperative courses indistinguishable from the remainder of the group. We conclude that surgery in patients with ABTs less than 2.3% is associated with extremely high mortality. In addition, cirrhotics with normal ABTs tolerate elective surgery well. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (630K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - Greenwood SM, Leffler CT, Minkowitz S. The increased mortality rate of open liver biopsy in alcoholic hepatitis. Surg Gynecol Obstet. 1972 Apr;134(4):600–604. [PubMed]
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