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Br Med J (Clin Res Ed). Jul 26, 1986; 293(6541): 237–239.
PMCID: PMC1341173

Prevalence of multiple sclerosis in a south London borough.

Abstract

A survey of multiple sclerosis in the London Borough of Sutton, population 169,600, yielded 195 cases, giving an overall prevalence of 115/100,000. This is the third highest prevalence for a first survey of a geographical area in the United Kingdom, exceeded only by 127/100,000 in north east Scotland and 134/100,000 in Shetland. On the classification system of Allison and Millar, three quarters of the cases were classified as probable multiple sclerosis, 15% as early probable and latent multiple sclerosis, and 10% as possible multiple sclerosis. The mean age was 49 years, the mean age at onset was 34 years, and the mean duration of the disease was 15.4 years. The age standardised female to male ratio was 2:1. The prevalence found in this survey does not differ significantly from that recorded in the first north east Scotland survey. This study suggests that, firstly, the prevalence of multiple sclerosis in south east England is probably about 100/100,000 and, secondly, the latitudinal effect on the prevalence of multiple sclerosis in the United Kingdom is less appreciable than previously believed.

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Selected References

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  • SUTHERLAND JM. Observations on the prevalence of multiple sclerosis in Northern Scotland. Brain. 1956 Dec;79(4):635–654. [PubMed]
  • POSKANZER DC, SCHAPIRA K, MILLER H. EPIDEMIOLOGY OF MULTIPLE SCLEROSIS IN THE COUNTIES OF NORTHUMBERLAND AND DURHAM. J Neurol Neurosurg Psychiatry. 1963 Aug;26:368–376. [PMC free article] [PubMed]
  • Fog M, Hyllested K. Prevalence of disseminated sclerosis in the Faroes, the Orkneys and Shetland. Acta Neurol Scand. 1966;42(Suppl):9–11. [PubMed]
  • Poskanzer DC, Prenney LB, Sheridan JL, Kondy JY. Multiple sclerosis in the Orkney and Shetland Islands. I: Epidemiology, clinical factors, and methodology. J Epidemiol Community Health. 1980 Dec;34(4):229–239. [PMC free article] [PubMed]
  • Shepherd DI, Downie AW. Prevalence of multiple sclerosis in north-east Scotland. Br Med J. 1978 Jul 29;2(6133):314–316. [PMC free article] [PubMed]
  • Shepherd DI, Downie AW. A further prevalence study of multiple sclerosis in north-east Scotland. J Neurol Neurosurg Psychiatry. 1980 Apr;43(4):310–315. [PMC free article] [PubMed]
  • HARGREAVES ER. Epidemiological studies in Cornwall. Proc R Soc Med. 1961 Mar;54:209–216. [PMC free article] [PubMed]
  • Kurtzke JF. Geographic distribution of multiple sclerosis: An update with special reference to Europe and the Mediterranean region. Acta Neurol Scand. 1980 Aug;62(2):65–80. [PubMed]
  • LIMBURG CC. The geographic distribution of multiple sclerosis and its estimated prevalence in the United States. Res Publ Assoc Res Nerv Ment Dis. 1950;28:15–24. [PubMed]

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