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Journal List > Trans Am Ophthalmol Soc > v.79; 1981

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Trans Am Ophthalmol Soc. 1981; 79: 810–839.
PMCID: PMC1312204
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A long-term follow-up study of cystoid macular edema in aphakic and pseudophakic eyes.
C P Wilkinson
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Abstract
Forty-four aphakic and 45 pseudophakic eyes with typical cystoid macular edema following cataract surgery were reevaluated one to four years following their initial fluorescein angiograms in an effort to compare the natural courses of the macular lesions in the two groups of eyes. Both aphakic and pseudophakic eyes in which the edema was associated with vitreous adhesions to the cataract wound experienced a lower rate of resolution than comparable cases without such adhesions. Macular edema cleared significantly more frequently in aphakic eyes than in pseudophakic cases. Pseudophakic eyes in which iris fixation had been employed had a particularly poor prognosis, which was significantly worse than the natural course observed in pseudophakic eyes associated with capsular fixation. The latter group of eyes cleared significantly less frequently than did the group of aphakic eyes without vitreous adhesions. The reasons that the natural course of cystoid macular edema in pseudophakic eyes is relatively poor are unknown, but chronic inflammation may play a significant role in the pathogenesis of this important complication.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Meredith TA, Kenyon KR, Singerman LJ, Fine SL. Perifoveal vascular leakage and macular oedema after intracapsular cataract extraction. Br J Ophthalmol. 1976 Nov;60(11):765–769. [PubMed]
  • IRVINE SR. A newly defined vitreous syndrome following cataract surgery. Am J Ophthalmol. 1953 May;36(5):499–619. [PubMed]
  • KIRSCH RE, STEINMAN W. Spontaneous rupture of the anterior hyaloid membrane following intracapsular cataract surgery. Am J Ophthalmol. 1954 May;37(5):657–665. [PubMed]
  • CHANDLER PA. Complications after cataract extraction: clinical aspects. Trans Am Acad Ophthalmol Otolaryngol. 1954 May–Jun;58(3):382–396. [PubMed]
  • NICHOLLS JV. Macular edema in association with cataract extraction. Am J Ophthalmol. 1954 May;37(5):665–672. [PubMed]
  • WELCH RB, COOPER JC. Macular edema, papilledema, and optic atrophy after cataract extraction. AMA Arch Ophthalmol. 1958 May;59(5):665–675. [PubMed]
  • GARTNER S. OPTIC NEURITIS AND MACULAR EDEMA FOLLOWING CATARACT EXTRACTION. Eye Ear Nose Throat Mon. 1964 Feb;43:45–49. [PubMed]
  • REESE AB, CARROLL FD. Optic neuritis following cataract extraction. Trans Am Acad Ophthalmol Otolaryngol. 1958 Nov–Dec;62(6):765–770. [PubMed]
  • Gass JD, Norton EW. Cystoid macular edema and papilledema following cataract extraction. A fluorescein fundoscopic and angiographic study. Arch Ophthalmol. 1966 Nov;76(5):646–661. [PubMed]
  • DUNNINGTON JH, REGAN EF. Late fistulization of operative wounds; diagnosis and treatment. Trans Am Ophthalmol Soc. 1949;47:63–79. [PubMed]
  • Tolentino FI, Schepens CL. Edema of posterior pole after cataract extraction. A biomicroscopic study. Arch Ophthalmol. 1965 Dec;74(6):781–786. [PubMed]
  • Reese AB, Jones IS, Cooper WC. Macular changes secondary to vitreous traction. Trans Am Ophthalmol Soc. 1966;64:123–134. [PubMed]
  • Maumenee AE. Further advances in the study of the macula. Arch Ophthalmol. 1967 Aug;78(2):151–165. [PubMed]
  • Jaffe NS. Vitreous traction at the posterior pole of the fundus due to alterations in the vitreous posterior. Trans Am Acad Ophthalmol Otolaryngol. 1967 Jul–Aug;71(4):642–652. [PubMed]
  • Irvine AR. Cystoid maculopathy. Surv Ophthalmol. 1976 Jul–Aug;21(1):1–17. [PubMed]
  • WELCH RB, MAUMENEE AE, WAHLEN HE. Peripheral posterior segment inflammation, vitreous opacities, and edema of the posterior pole. Arch Ophthalmol. 1960 Oct;64:540–549. [PubMed]
  • Maumenee AE. Clinical entities in "uveitis": an approach to the study of intraocular inflammation. Trans Am Acad Ophthalmol Otolaryngol. 1970 May–Jun;74(3):473–504. [PubMed]
  • Ryan SJ., Jr Cystoid maculopathy in phakic retinal detachment procedures. Am J Ophthalmol. 1973 Oct;76(4):519–522. [PubMed]
  • West CE, Fitzgerald CR, Sewell JH. Cystoid macular edema following aphakic keratoplasty. Am J Ophthalmol. 1973 Jan;75(1):77–81. [PubMed]
  • Kimball RW, Morse PH, Benson WE. Cystoid macular edema after cryotherapy. Am J Ophthalmol. 1978 Oct;86(4):572–573. [PubMed]
  • Lobes LA, Jr, Grand MG. Incidence of cystoid macular edema following scleral buckling procedure. Arch Ophthalmol. 1980 Jul;98(7):1230–1232. [PubMed]
  • Wilkinson CP, Rowsey JJ. Closed vitrectomy for the vitreous touch syndrome. Am J Ophthalmol. 1980 Sep;90(3):304–308. [PubMed]
  • Kramer SG. Cystoid macular edema after aphakic penetrating keratoplasty. Ophthalmology. 1981 Aug;88(8):782–787. [PubMed]
  • Kottow M, Hendrickson P. Iris angiography in cystoid macular edema after cataract extraction. Arch Ophthalmol. 1975 Jul;93(7):487–493. [PubMed]
  • Easty D, Dallas N, O'Malley R. Aphakic macular oedema following prosthetic lens implantation. Br J Ophthalmol. 1977 May;61(5):321–326. [PubMed]
  • Norton AL, Brown WJ, Carlson M, Pilger IS, Riffenburgh RS. Pathogenesis of aphakic macular edema. Am J Ophthalmol. 1975 Jul;80(1):96–101. [PubMed]
  • Martin NF, Green WR, Martin LW. Retinal phlebitis in the Irvine-Gass syndrome. Am J Ophthalmol. 1977 Mar;83(3):377–386. [PubMed]
  • Miyake K. Prophylaxis of aphakic cystoid macular edema using topical indomethacin. J Am Intraocul Implant Soc. 1978 Oct;4(4):174–179. [PubMed]
  • Yannuzzi LA, Klein RM, Wallyn RH, Cohen N, Katiz I. Ineffectiveness of indomethacin in the treatment of chronic cystoid macular edema. Am J Ophthalmol. 1977 Oct;84(4):517–519. [PubMed]
  • Obstbaum SA, Galin MA. Cystoid macular oedema and ocular inflammation. The corneo-retinal inflammatory syndrome. Trans Ophthalmol Soc U K. 1979 Apr;99(1):187–191. [PubMed]
  • Binkhorst CD. Corneal and retinal complications after cataract extraction. The mechanical aspect of endophthalmodonesis. Ophthalmology. 1980 Jul;87(7):609–617. [PubMed]
  • Worst J. Extracapsular surgery in lens implantation (Binkhorst lecture). Part iv. Some anatomical and pathophysiological implications. J Am Intraocul Implant Soc. 1978 Jan;4(1):7–14. [PubMed]
  • Kolker AE, Becker B. Epinephrine maculopathy. Arch Ophthalmol. 1968 May;79(5):552–562. [PubMed]
  • Michels RG, Maumenee AE. Cystoid macular edema associated with topically applied epinephrine in aphakic eyes. Am J Ophthalmol. 1975 Sep;80(3 Pt 1):379–388. [PubMed]
  • Roper DL, Nisbet RM. Effect of hyaluronidase on the incidence of cystoid macular edema. Ann Ophthalmol. 1978 Dec;10(12):1673–1678. [PubMed]
  • Henry MM, Henry LM, Henry LM. A possible cause of chronic cystic maculopathy. Ann Ophthalmol. 1977 Apr;9(4):455–457. [PubMed]
  • Tso MO, Shih CY. Experimental macular edema after lens extraction. Invest Ophthalmol Vis Sci. 1977 May;16(5):381–392. [PubMed]
  • Irvine AR. Extracapsular cataract extraction and pseudophakos implantation in primates: a clinico-pathologic study. Trans Am Ophthalmol Soc. 1980;78:780–807. [PubMed]
  • Kramer SG. Considerations on epinephrine therapy in glaucoma. Ann Ophthalmol. 1978 Aug;10(8):1077–1078. [PubMed]
  • Klein RM, Katzin HM, Yannuzzi LA. The effect of indomethacin pretreatment on aphakic cystoid macular edema. Am J Ophthalmol. 1979 Apr;87(4):487–489. [PubMed]
  • Gass JD, Norton EW. Follow-up study of cystoid macular edema following cataract extraction. Trans Am Acad Ophthalmol Otolaryngol. 1969 Jul–Aug;73(4):665–682. [PubMed]
  • Jacobson DR, Dellaporta A. Natural history of cystoid macular edema after cataract extraction. Am J Ophthalmol. 1974 Apr;77(4):445–447. [PubMed]
  • Hitchings RA, Chisholm IH, Bird AC. Aphakic macular edema: incidence and pathogenesis. Invest Ophthalmol. 1975 Jan;14(1):68–72. [PubMed]
  • Hitchings RA. Aphakic macular oedema: a two-year follow-up study. Br J Ophthalmol. 1977 Oct;61(10):628–630. [PubMed]
  • Berrocal JA. Incidence of cystoid macular edema after different cataract operations. Mod Probl Ophthalmol. 1977;18:518–520. [PubMed]
  • Fung WE. Phacoemulsification. Ophthalmology. 1978 Jan;85(1):46–51. [PubMed]
  • Winslow RL, Taylor BC, Harris WS. A one-year follow-up of cystoid macular edema following intraocular lens implantation. Ophthalmology. 1978 Feb;85(2):190–196. [PubMed]
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