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Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
Thomas Pap, Ulf Müller-Ladner, Renate E Gay, Steffen Gay
Arthritis Res. 2000; 2(5): 361–367. Published online 2000 June 8. doi: 10.1186/ar113
PMCID:
PMC130137
Abstract Full Text PDF–212K

Is Cited by the Following 50 Articles in this Archive:

Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change
Kurt R. Stenmark, Maria G. Frid, Michael Yeager, Min Li, Suzette Riddle, Timothy McKinsey, Karim C. El Kasmi
Pulm Circ. 2012 Jan-Mar; 2(1): 3–14. doi: 10.4103/2045-8932.94817
PMCID:
PMC3342746
Abstract Full Text
Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70
Devapregasan Moodley, Girish M Mody, Anil A Chuturgoon
J Inflamm (Lond) 2011; 8: 30. Published online 2011 November 3. doi: 10.1186/1476-9255-8-30
PMCID:
PMC3215641
Abstract Full Text PDF–1.3M
Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets
Xinli Hu, Hyun Kim, Eli Stahl, Robert Plenge, Mark Daly, Soumya Raychaudhuri
Am J Hum Genet. 2011 October 7; 89(4): 496–506. doi: 10.1016/j.ajhg.2011.09.002
Correction in:
Am J Hum Genet. 2011 November 11; 89(5): 682.
PMCID:
PMC3188838
Abstract Full Text PDF–624K Supplementary Material Correction
High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts
Heidi Wähämaa, Hanna Schierbeck, Hulda S Hreggvidsdottir, Karin Palmblad, Anne-Charlotte Aveberger, Ulf Andersson, Helena Erlandsson Harris
Arthritis Res Ther. 2011; 13(4): R136. Published online 2011 August 26. doi: 10.1186/ar3450
PMCID:
PMC3239379
Abstract Full Text PDF–569K
EMERGENCE OF FIBROBLASTS WITH A PROINFLAMMATORY EPIGENETICALLY ALTERED PHENOTYPE IN SEVERE HYPOXIC PULMONARY HYPERTENSION
Min Li, Suzette R. Riddle, Maria G. Frid, Karim C. El Kasmi, Timothy A. McKinsey, Ronald J. Sokol, Derek Strassheim, Barbara Meyrick, Michael E. Yeager, Amanda R. Flockton, B. Alexandre McKeon, Douglas D. Lemon, Todd R. Horn, Adil Anwar, Carlos Barajas, Kurt R. Stenmark
J Immunol. Author manuscript; available in PMC 2012 September 1.
Published in final edited form as: J Immunol. 2011 September 1; 187(5): 2711–2722. Published online 2011 August 3. doi: 10.4049/jimmunol.1100479
PMCID:
PMC3159707
Free in PMC on 2012/09/01
A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases
Nishkantha Arulkumaran, Robert J. Unwin, Frederick W. K. Tam
Expert Opin Investig Drugs. Author manuscript; available in PMC 2011 July 1.
Published in final edited form as: Expert Opin Investig Drugs. 2011 July; 20(7): 897–915. Published online 2011 April 21. doi: 10.1517/13543784.2011.578068
PMCID:
PMC3114873
Abstract Full Text PDF–391K
Adrenomedullin increases fibroblast-like synoviocyte adhesion to extracellular matrix proteins by upregulating integrin activation
Marie-Dominique Ah Kioon, Carine Asensio, Hang-Korng Ea, Benjamin Uzan, Martine Cohen-Solal, Frédéric Lioté
Arthritis Res Ther. 2010; 12(5): R190. Published online 2010 October 14. doi: 10.1186/ar3160
PMCID:
PMC2991025
Abstract Full Text PDF–1.1M
BRAF Drives Synovial Fibroblast Transformation in Rheumatoid Arthritis
Richard H. Weisbart, Grace Chan, Emil Heinze, Rachel Mory, Robert N. Nishimura, Keith Colburn
J Biol Chem. 2010 November 5; 285(45): 34299–34303. Published online 2010 September 15. doi: 10.1074/jbc.C110.168195
PMCID:
PMC2966042
Abstract Full Text
Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
Elena Neumann, Birgit Riepl, Anette Knedla, Stephanie Lefèvre, Ingo H Tarner, Joachim Grifka, Jurgen Steinmeyer, Jurgen Schölmerich, Steffen Gay, Ulf Müller-Ladner
Arthritis Res Ther. 2010; 12(3): R83. Published online 2010 May 12. doi: 10.1186/ar3010
PMCID:
PMC2911867
Abstract Full Text PDF–901K
Increased Cytokine Production in Interleukin-18 Receptor α-deficient Cells Is Associated with Dysregulation of Suppressors of Cytokine Signaling
Claudia A. Nold-Petry, Marcel F. Nold, Jason W. Nielsen, Alex Bustamante, Jarod A. Zepp, Kathleen A. Storm, Jae-Woo Hong, Soo-Hyun Kim, Charles A. Dinarello
J Biol Chem. 2009 September 18; 284(38): 25900–25911. Published online 2009 July 10. doi: 10.1074/jbc.M109.004184
PMCID:
PMC2757991
Abstract Full Text
Galectin 3 Induces a Distinctive Pattern of Cytokine and Chemokine Production in Rheumatoid Synovial Fibroblasts via Selective Signaling Pathways
Andrew Filer, Magdalena Bik, Greg N. Parsonage, John Fitton, Emily Trebilcock, Katherine Howlett, Michelle Cook, Karim Raza, David L. Simmons, Andrew M. C. Thomas, Mike Salmon, Dagmar Scheel-Toellner, Janet M. Lord, Gabriel A. Rabinovich, Christopher D. Buckley
Arthritis Rheum. Author manuscript; available in PMC 2011 June 16.
Published in final edited form as: Arthritis Rheum. 2009 June; 60(6): 1604–1614. doi: 10.1002/art.24574
PMCID:
PMC3116228
Abstract Full Text PDF–457K
In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage
David Pretzel, Dirk Pohlers, Sönke Weinert, Raimund W Kinne
Arthritis Res Ther. 2009; 11(1): R25. Published online 2009 February 18. doi: 10.1186/ar2618
PMCID:
PMC2688258
Abstract Full Text PDF–5.5M
Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent
Noreen Pundt, Marvin A Peters, Christina Wunrau, Simon Strietholt, Carsten Fehrmann, Katja Neugebauer, Christine Seyfert, Frans van Valen, Thomas Pap, Ingmar Meinecke
Arthritis Res Ther. 2009; 11(1): R16. Published online 2009 February 5. doi: 10.1186/ar2607
PMCID:
PMC2688248
Abstract Full Text PDF–1.2M
Immune interactions in hepatic fibrosis. or “Leucocyte-stromal interactions in hepatic fibrosis”
Andrew P Holt, Mike Salmon, Christopher D Buckley, David H Adams
Clin Liver Dis. Author manuscript; available in PMC 2009 November 1.
Published in final edited form as: Clin Liver Dis. 2008 November; 12(4): 861–x. doi: 10.1016/j.cld.2008.07.002
PMCID:
PMC2605646
Abstract Full Text PDF–978K
Fibroblasts as novel therapeutic targets in chronic inflammation
S J Flavell, T Z Hou, S Lax, A D Filer, M Salmon, C D Buckley
Br J Pharmacol. 2008 March; 153(S1): S241–S246. Published online 2007 October 29. doi: 10.1038/sj.bjp.0707487
PMCID:
PMC2268075
Abstract Full Text PDF–136K
The GTPase Rac Regulates the Proliferation and Invasion of Fibroblast-Like Synoviocytes from Rheumatoid Arthritis Patients
Amanda Chan, Mumtaz Akhtar, Max Brenner, Yi Zheng, Percio S Gulko, Marc Symons
Mol Med. 2007 May-Jun; 13(5-6): 297–304. doi: 10.2119/2007-00025.Chan
PMCID:
PMC1906689
Abstract Full Text PDF–1.1M
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts
Ingmar Meinecke, Antje Cinski, Anja Baier, Marvin A. Peters, Berno Dankbar, Aline Wille, Andreas Drynda, Heidi Mendoza, Renate E. Gay, Ronald T. Hay, Barbara Ink, Steffen Gay, Thomas Pap
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5073–5078. Published online 2007 March 14. doi: 10.1073/pnas.0608773104
PMCID:
PMC1829266
Abstract Full Text PDF–552K
Proinflammatory cytokine synthesis by mucosal fibroblasts from mouse colitis is enhanced by interferon-γ-mediated up-regulation of CD40 signalling
Karlson T De L, C V Whiting, P W Bland
Clin Exp Immunol. 2007 February; 147(2): 313–323. doi: 10.1111/j.1365-2249.2006.03267.x
Correction in:
Clin Exp Immunol. 2007 April; 148(1): 188.
PMCID:
PMC1810481
Abstract Full Text PDF–626K Correction
MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis
Jinah Jang, Dae-Seog Lim, Young-Eun Choi, Yong Jeong, Seung-Ah Yoo, Wan-Uk Kim, Yong-Soo Bae
Arthritis Res Ther. 2006; 8(6): R170. Published online 2006 November 14. doi: 10.1186/ar2079
PMCID:
PMC1794514
Abstract Full Text PDF–879K
An essential role of NF-κB in the “tumor-like” phenotype of arthritic synoviocytes
Xiangli Li, Sergei S. Makarov
Proc Natl Acad Sci U S A. 2006 November 14; 103(46): 17432–17437. Published online 2006 November 6. doi: 10.1073/pnas.0607939103
PMCID:
PMC1859946
Abstract Full Text PDF–665K
Local treatment with the selective IκB kinase β inhibitor NEMO-binding domain peptide ameliorates synovial inflammation
Sander W Tas, Margriet J Vervoordeldonk, Najat Hajji, Michael J May, Sankar Ghosh, Paul P Tak
Arthritis Res Ther. 2006; 8(4): R86. Published online 2006 May 9. doi: 10.1186/ar1958
PMCID:
PMC1779420
Abstract Full Text PDF–892K
Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis
Tetsuya Honda, Eri Segi-Nishida, Yoshiki Miyachi, Shuh Narumiya
J Exp Med. 2006 February 20; 203(2): 325–335. doi: 10.1084/jem.20051310
PMCID:
PMC2118213
Abstract Full Text PDF–1.6M Supplementary Material
The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis
Pnina Fishman, Sara Bar-Yehuda, Lea Madi, Lea Rath-Wolfson, Avivit Ochaion, Shira Cohen, Ehud Baharav
Arthritis Res Ther. 2006; 8(1): R33. Published online 2006 January 13. doi: 10.1186/ar1887
PMCID:
PMC1526584
Abstract Full Text PDF–844K
A Novel Mechanism of Neutrophil Recruitment in a Coculture Model of the Rheumatoid Synovium
Frank Lally, Emily Smith, Andrew Filer, Michael A. Stone, John S. Shaw, Gerard B. Nash, Christopher D. Buckley, G. Ed Rainger
Arthritis Rheum. Author manuscript; available in PMC 2011 June 21.
Published in final edited form as: Arthritis Rheum. 2005 November; 52(11): 3460–3469. doi: 10.1002/art.21394
PMCID:
PMC3119436
Abstract Full Text PDF–1.1M
Insights into the role of fibroblasts in human autoimmune diseases
TJ Smith
Clin Exp Immunol. 2005 September; 141(3): 388–397. doi: 10.1111/j.1365-2249.2005.02824.x
PMCID:
PMC1809453
Abstract Full Text PDF–303K
Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease
Satoshi Yamasaki, Naoko Yagishita, Kaneyuki Tsuchimochi, Kusuki Nishioka, Toshihiro Nakajima
Arthritis Res Ther. 2005; 7(5): 181–186. Published online 2005 August 17. doi: 10.1186/ar1808
PMCID:
PMC1257448
Abstract Full Text PDF–316K
MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle?
Lars-Henrik Meyer, Thomas Pap
Arthritis Res Ther. 2005; 7(5): 177–178. Published online 2005 August 16. doi: 10.1186/ar1810
PMCID:
PMC1257450
Abstract Full Text PDF–39K
Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production
Ping Zhu, Jin Ding, Jun Zhou, Wei-Jia Dong, Chun-Mei Fan, Zhi-Nan Chen
Arthritis Res Ther. 2005; 7(5): R1023–R1033. Published online 2005 June 23. doi: 10.1186/ar1778
PMCID:
PMC1257431
Abstract Full Text PDF–1.2M
The needle and the damage done*
J Franz, G Burmester
Ann Rheum Dis. 2005 June; 64(6): 798–800. doi: 10.1136/ard.2005.039248
PMCID:
PMC1755515
Summary PDF–61K
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin
Karim Raza, Francesco Falciani, S John Curnow, Emma J Ross, Chi-Yeung Lee, Arne N Akbar, Janet M Lord, Caroline Gordon, Christopher D Buckley, Mike Salmon
Arthritis Res Ther. 2005; 7(4): R784–R795. Published online 2005 April 7. doi: 10.1186/ar1733
PMCID:
PMC1175027
Abstract Full Text PDF–519K
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