pmc logo image
Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period?
Dan Qiao, Frederic J Seidler, Stephanie Padilla, and Theodore A Slotkin
Environ Health Perspect. 2002 November; 110(11): 1097–1103.
PMCID: PMC1241065
 Is Cited by the Following Articles in this Archive:
Potential developmental neurotoxicity of pesticides used in Europe
Marina Bjørling-Poulsen, Helle Raun Andersen, and Philippe Grandjean
Environ Health. 2008; 7: 50. Published online 2008 October 22. doi: 10.1186/1476-069X-7-50.
PMCID: PMC2577708
Long-Term Effects on Hypothalamic Neuropeptides after Developmental Exposure to Chlorpyrifos in Mice
Sabrina Tait, Laura Ricceri, Aldina Venerosi, Francesca Maranghi, Alberto Mantovani, and Gemma Calamandrei
Environ Health Perspect. 2009 January; 117(1): 112–116. Published online 2008 August 22. doi: 10.1289/ehp.11696.
PMCID: PMC2627853
Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Impairment of Acetylcholine Systems in Brain Regions during Adolescence and Adulthood
Theodore A. Slotkin, Bethany E. Bodwell, Ian T. Ryde, Edward D. Levin, and Frederic J. Seidler
Environ Health Perspect. 2008 October; 116(10): 1308–1314. Published online 2008 May 19. doi: 10.1289/ehp.11451.
PMCID: PMC2569087
Neonatal Exposure to Low Doses of Diazinon: Long-Term Effects on Neural Cell Development and Acetylcholine Systems
Theodore A. Slotkin, Bethany E. Bodwell, Edward D. Levin, and Frederic J. Seidler
Environ Health Perspect. 2008 March; 116(3): 340–348. Published online 2007 December 13. doi: 10.1289/ehp.11005.
PMCID: PMC2265026
Developmental Neurotoxicity of Low-Dose Diazinon Exposure of Neonatal Rats: Effects on Serotonin Systems in Adolescence and Adulthood
Theodore A. Slotkin, Ian T. Ryde, Edward D. Levin, and Frederic J. Seidler
Brain Res Bull. Author manuscript; available in PMC 2009 March 28.
PMCID: PMC2322865
Published in final edited form as: Brain Res Bull. 2008 March 28; 75(5): 640–647. Published online 2007 November 12. doi: 10.1016/j.brainresbull.2007.10.008.
Manuscript: | Abstract | Full Text | PDF–893K |
Comparative Developmental Neurotoxicity of Organophosphates In Vivo: Transcriptional Responses of Pathways for Brain Cell Development, Cell Signaling, Cytotoxicity and Neurotransmitter Systems
Theodore A. Slotkin and Frederic J. Seidler
Brain Res Bull. Author manuscript; available in PMC 2008 May 30.
PMCID: PMC1945108
Published in final edited form as: Brain Res Bull. 2007 May 30; 72(4-6): 232–274. Published online 2007 January 25. doi: 10.1016/j.brainresbull.2007.01.005.
Manuscript: | Abstract | Full Text | PDF–3.3M |
Organophosphate Insecticides Target the Serotonergic System in Developing Rat Brain Regions: Disparate Effects of Diazinon and Parathion at Doses Spanning the Threshold for Cholinesterase Inhibition
Theodore A. Slotkin, Charlotte A. Tate, Ian T. Ryde, Edward D. Levin, and Frederic J. Seidler
Environ Health Perspect. 2006 October; 114(10): 1542–1546. Published online 2006 July 27. doi: 10.1289/ehp.9337.
PMCID: PMC1626396
Organophosphates and Outdoor Air Concentrations
Robert K.D. Peterson
Environ Health Perspect. 2006 June; 114(6): A338–A339.
PMCID: PMC1480511
Organophosphates and Outdoor Air: Harnly et al. Respond
Martha Harnly, Robert McLaughlin, Robert Gunier, Asa Bradman, and Meredith Anderson
Environ Health Perspect. 2006 June; 114(6): A339–A340.
PMCID: PMC1480530
Comparative Developmental Neurotoxicity of Organophosphate Insecticides: Effects on Brain Development Are Separable from Systemic Toxicity
Theodore A. Slotkin, Edward D. Levin, and Frederic J. Seidler
Environ Health Perspect. 2006 May; 114(5): 746–751. Published online 2006 February 2. doi: 10.1289/ehp.8828.
PMCID: PMC1459930
A Case for Revisiting the Safety of Pesticides: A Closer Look at Neurodevelopment
Theo Colborn
Environ Health Perspect. 2006 January; 114(1): 10–17. Published online 2005 September 7. doi: 10.1289/ehp.7940.
PMCID: PMC1332649
Correlating Agricultural Use of Organophosphates with Outdoor Air Concentrations: A Particular Concern for Children
Martha Harnly, Robert McLaughlin, Asa Bradman, Meredith Anderson, and Robert Gunier
Environ Health Perspect. 2005 September; 113(9): 1184–1189. Published online 2005 May 13. doi: 10.1289/ehp.7493.
PMCID: PMC1280399
Alterations in Central Nervous System Serotonergic and Dopaminergic Synaptic Activity in Adulthood after Prenatal or Neonatal Chlorpyrifos Exposure
Justin E. Aldridge, Armando Meyer, Frederic J. Seidler, and Theodore A. Slotkin
Environ Health Perspect. 2005 August; 113(8): 1027–1031. Published online 2005 April 28. doi: 10.1289/ehp.7968.
PMCID: PMC1280344
Developmental Exposure of Rats to Chlorpyrifos Leads to Behavioral Alterations in Adulthood, Involving Serotonergic Mechanisms and Resembling Animal Models of Depression
Justin E. Aldridge, Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin
Environ Health Perspect. 2005 May; 113(5): 527–531. Published online 2005 February 2. doi: 10.1289/ehp.7867.
PMCID: PMC1257542
Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure.
Armando Meyer, Frederic J Seidler, Justin E Aldridge, Charlotte A Tate, Mandy M Cousins, and Theodore A Slotkin
Environ Health Perspect. 2004 March; 112(3): 295–301.
PMCID: PMC1241857
Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling.
Justin E Aldridge, Frederic J Seidler, and Theodore A Slotkin
Environ Health Perspect. 2004 February; 112(2): 148–155.
PMCID: PMC1241823
Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling.
Armando Meyer, Frederic J Seidler, and Theodore A Slotkin
Environ Health Perspect. 2004 February; 112(2): 170–178.
PMCID: PMC1241826
Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target?
Armando Meyer, Frederic J Seidler, Mandy M Cousins, and Theodore A Slotkin
Environ Health Perspect. 2003 December; 111(16): 1871–1876.
PMCID: PMC1241759
Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods.
Justin E Aldridge, Frederic J Seidler, Armando Meyer, Indira Thillai, and Theodore A Slotkin
Environ Health Perspect. 2003 November; 111(14): 1736–1743.
PMCID: PMC1241716
Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood.
Dan Qiao, Frederic J Seidler, Charlotte A Tate, Mandy M Cousins, and Theodore A Slotkin
Environ Health Perspect. 2003 April; 111(4): 536–544.
PMCID: PMC1241441
Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospecific proteins indicate changing vulnerabilities.
Stephanie J Garcia, Frederic J Seidler, and Theodore A Slotkin
Environ Health Perspect. 2003 March; 111(3): 297–303.
PMCID: PMC1241386