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Ann Surg. 1995 Nov; 222(5): 654–662.
PMCID: PMC1234993

Mortality and morbidity rates, postoperative course, quality of life, and prognosis after extended radical lymphadenectomy for esophageal cancer. Comparison of three-field lymphadenectomy with two-field lymphadenectomy.


PURPOSE: The authors evaluated the efficacy of extended radical (three-field) lymphadenectomy for esophageal cancer compared with less radical (two-field) lymphadenectomy. STUDY SUBJECTS AND ANALYTIC METHODS: The mortality and morbidity rates, postoperative courses, and survival rates were compared between 63 patients who underwent three-field lymph node dissection and 65 who underwent two-field lymph node dissection at Kurume University Hospital from 1986 to 1991. Long-term quality of life after surgery was compared between 37 patients who underwent three-field dissection and 35 who underwent two-field dissection from 1980 to 1991. RESULTS: Three-field dissection resulted in better survival for patients with positive lymph node metastasis from a carcinoma in the upper thoracic or midthoracic esophagus compared with two-field dissection. The mortality rates, postoperative courses and quality of life were the same for both procedures. CONCLUSIONS: Three-field dissection is preferred for upper thoracic or midthoracic esophageal cancer because of improved survival, acceptable mortality and morbidity rates, and good postoperative course and quality of life.

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Selected References

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  • Kato H, Watanabe H, Tachimori Y, Iizuka T. Evaluation of neck lymph node dissection for thoracic esophageal carcinoma. Ann Thorac Surg. 1991 Jun;51(6):931–935. [PubMed]
  • Zhang GH, Fujita H, Yamana H, Kakegawa T. A prediction of hospital mortality after surgical treatment for esophageal cancer. Surg Today. 1994;24(2):122–127. [PubMed]
  • Isono K, Ochiai T, Okuyama K, Onoda S. The treatment of lymph node metastasis from esophageal cancer by extensive lymphadenectomy. Jpn J Surg. 1990 Mar;20(2):151–157. [PubMed]
  • Noguchi Y, Baba M, Nakano S, Fukumoto T, Yoshinaka H, Aikou T, Shimazu H. [Quality of life of patients after esophagectomy for esophageal cancer]. Nihon Geka Gakkai Zasshi. 1991 Mar;92(3):281–287. [PubMed]
  • Hirano M, Tanaka S, Fujita M, Fujita H. Vocal cord paralysis caused by esophageal cancer surgery. Ann Otol Rhinol Laryngol. 1993 Mar;102(3 Pt 1):182–185. [PubMed]
  • Fujita H, Hawahara H, Yamana H, Shirohazu G, Yoshimura Y, Minami T, Negoto Y, Irie H, Shima I, Machi J, et al. Mediastinal lymphnode dissection procedure during esophageal cancer operation--carefully considered for preserving respiratory function. Jpn J Surg. 1988 Jan;18(1):31–34. [PubMed]
  • Skinner DB. En bloc resection for neoplasms of the esophagus and cardia. J Thorac Cardiovasc Surg. 1983 Jan;85(1):59–71. [PubMed]
  • Fujita H, Kawahara H, Hidaka M, Nagano T, Yoshimatsu H. An experimental study on viability of the devascularized trachea. Jpn J Surg. 1988 Jan;18(1):77–83. [PubMed]
  • Isono K, Sato H, Nakayama K. Results of a nationwide study on the three-field lymph node dissection of esophageal cancer. Oncology. 1991;48(5):411–420. [PubMed]
  • Fujita H, Kakegawa T, Yamana H, Shima I, Rikitake H, Hyodo M, Yokoyama T, Fujii T, Toh U, Tsugane S. Cervico-thoraco-abdominal (3-field) lymph node dissection for carcinoma in the thoracic esophagus. Kurume Med J. 1992;39(3):167–174. [PubMed]
  • Fujita H, Kakegawa T, Yamana H, Shima I, Tanaka H, Ikeda S, Nogami S, Toh Y. Lymph node metastasis and recurrence in patients with a carcinoma of the thoracic esophagus who underwent three-field dissection. World J Surg. 1994 Mar-Apr;18(2):266–272. [PubMed]

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