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Biochem J. Jul 15, 2002; 365(Pt 2): 343–347.
PMCID: PMC1222701

Fate of haem iron in the malaria parasite Plasmodium falciparum.


Chemical analysis has shown that Plasmodium falciparum trophozoites contain 61+/-2% of the iron within parasitized erythrocytes, of which 92+/-6% is located within the food vacuole. Of this, 88+/-9% is in the form of haemozoin. (57)Fe-Mössbauer spectroscopy shows that haemozoin is the only detectable iron species in trophozoites. Electron spectroscopic imaging confirms this conclusion.

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Selected References

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