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Genetics. Sep 1975; 81(1): 135–141.
PMCID: PMC1213379

Maleless, a Recessive Autosomal Mutant of DROSOPHILA MELANOGASTER That Specifically Kills Male Zygotes

Abstract

A second chromosome male-specific lethal gene, maleless ( mle), in D. melanogaster is described. It kills males but not females in homozygous condition, regardless of whether female parents are heterozygous or homozygous for mle. Many, if not most, homozygous males survive up to the third instar larval stage, but cannot pupate and die eventually as larvae. No interactions with sex-transforming genes, tra and dsx, were observed. It is proposed that mle interacts with a gene(s) on the X chromosome, which is not dosage compensated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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