• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of geneticsGeneticsCurrent IssueInformation for AuthorsEditorial BoardSubscribeSubmit a Manuscript
Genetics. Feb 1993; 133(2): 335–345.
PMCID: PMC1205323

Bari-1, a New Transposon-like Family in Drosophila Melanogaster with a Unique Heterochromatic Organization

Abstract

We have identified a new middle repetitive DNA family in Drosophila melanogaster. This family is composed of a 1.7-kb element, called Bari-1, that shows common characteristics with many transposable elements. Bari-1 is present in a few euchromatic sites that vary in different stocks. However, it is peculiar in that most copies are homogeneously clustered with a unique location in a specific heterochromatic region close to the centromere of the second chromosome. The molecular analysis of different copies coming from the euchromatin and the heterochromatin has revealed that, independent of their location, all possess the same open reading frame. The putative protein encoded by Bari-1 shares similarity with the transposase of the Tc1 transposon of Caenorhabditis elegans. We compare the Bari-1 organization with other mobile DNA families and discuss the possibility of some functional role for the heterochromatic cluster.

Full Text

The Full Text of this article is available as a PDF (5.4M).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Appels R, Peacock WJ. The arrangement and evolution of highly repeated (satellite) DNA sequences with special reference to Drosophila. Int Rev Cytol Suppl. 1978;Suppl 8:69–126. [PubMed]
  • Bonaccorsi S, Gatti M, Pisano C, Lohe A. Transcription of a satellite DNA on two Y chromosome loops of Drosophila melanogaster. Chromosoma. 1990 Aug;99(4):260–266. [PubMed]
  • Brezinsky L, Wang GV, Humphreys T, Hunt J. The transposable element Uhu from Hawaiian Drosophila--member of the widely dispersed class of Tc1-like transposons. Nucleic Acids Res. 1990 Apr 25;18(8):2053–2059. [PMC free article] [PubMed]
  • Brierley HL, Potter SS. Distinct characteristics of loop sequences of two Drosophila foldback transposable elements. Nucleic Acids Res. 1985 Jan 25;13(2):485–500. [PMC free article] [PubMed]
  • Devlin RH, Bingham B, Wakimoto BT. The organization and expression of the light gene, a heterochromatic gene of Drosophila melanogaster. Genetics. 1990 May;125(1):129–140. [PMC free article] [PubMed]
  • Emmons SW, Yesner L, Ruan KS, Katzenberg D. Evidence for a transposon in Caenorhabditis elegans. Cell. 1983 Jan;32(1):55–65. [PubMed]
  • Finnegan DJ. Eukaryotic transposable elements and genome evolution. Trends Genet. 1989 Apr;5(4):103–107. [PubMed]
  • Ganetzky B. On the components of segregation distortion in Drosophila melanogaster. Genetics. 1977 Jun;86(2 Pt 1):321–355. [PMC free article] [PubMed]
  • Hartl DL. Genetic dissection of segregation distortion II. Mechanism of suppression of distortion by certain inversions. Genetics. 1975 Jul;(3):539–547. [PMC free article] [PubMed]
  • Henikoff S, Plasterk RH. Related transposons in C.elegans and D.melanogaster. Nucleic Acids Res. 1988 Jul 11;16(13):6234–6234. [PMC free article] [PubMed]
  • Higgins DG, Sharp PM. CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. Gene. 1988 Dec 15;73(1):237–244. [PubMed]
  • Hiraizumi Y, Martin DW, Eckstrand IA. A Modified Model of Segregation Distortion in DROSOPHILA MELANOGASTER. Genetics. 1980 Jul;95(3):693–706. [PMC free article] [PubMed]
  • Hiraizumi Y, Thomas AM. Suppressor Systems of Segregation Distorter (SD) Chromosomes in Natural Populations of DROSOPHILA MELANOGASTER. Genetics. 1984 Feb;106(2):279–292. [PMC free article] [PubMed]
  • Liao LW, Rosenzweig B, Hirsh D. Analysis of a transposable element in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 1983 Jun;80(12):3585–3589. [PMC free article] [PubMed]
  • Lohe AR, Brutlag DL. Adjacent satellite DNA segments in Drosophila structure of junctions. J Mol Biol. 1987 Mar 20;194(2):171–179. [PubMed]
  • Lyttle TW. The effect of novel chromosome position and variable dose on the genetic behavior of the Responder (Rsp) element of the Segregation distorter (SD) system of Drosophila melanogaster. Genetics. 1989 Apr;121(4):751–763. [PMC free article] [PubMed]
  • Martin DW, Hiraizumi Y. On the Models of Segregation Distortion in DROSOPHILA MELANOGASTER. Genetics. 1979 Oct;93(2):423–435. [PMC free article] [PubMed]
  • Pardue ML, Hennig W. Heterochromatin: junk or collectors item? Chromosoma. 1990 Dec;100(1):3–7. [PubMed]
  • Pimpinelli S, Dimitri P. Cytogenetic analysis of segregation distortion in Drosophila melanogaster: the cytological organization of the Responder (Rsp) locus. Genetics. 1989 Apr;121(4):765–772. [PMC free article] [PubMed]
  • Pimpinelli S, Sullivan W, Prout M, Sandler L. On biological functions mapping to the heterochromatin of Drosophila melanogaster. Genetics. 1985 Apr;109(4):701–724. [PMC free article] [PubMed]
  • Rosenzweig B, Liao LW, Hirsh D. Sequence of the C. elegans transposable element Tc1. Nucleic Acids Res. 1983 Jun 25;11(12):4201–4209. [PMC free article] [PubMed]
  • Ruan KS, Emmons SW. Precise and imprecise somatic excision of the transposon Tc1 in the nematode C. elegans. Nucleic Acids Res. 1987 Sep 11;15(17):6875–6881. [PMC free article] [PubMed]
  • Sandler L. The Regulation of Sex Chromosome Heterochromatic Activity by an Autosomal Gene in DROSOPHILA MELANOGASTER. Genetics. 1970 Mar;64(3-4):481–493. [PMC free article] [PubMed]
  • Schukkink RF, Plasterk RH. TcA, the putative transposase of the C. elegans Tc1 transposon, has an N-terminal DNA binding domain. Nucleic Acids Res. 1990 Feb 25;18(4):895–900. [PMC free article] [PubMed]
  • Spradling AC, Rubin GM. Drosophila genome organization: conserved and dynamic aspects. Annu Rev Genet. 1981;15:219–264. [PubMed]
  • Temin RG, Marthas M. Factors Influencing the Effect of Segregation Distortion in Natural Populations of DROSOPHILA MELANOGASTER. Genetics. 1984 Jul;107(3):375–393. [PMC free article] [PubMed]
  • Tokuyasu KT, Peacock WJ, Hardy RW. Dynamics of spermiogenesis in Drosophila melanogaster. VII. Effects of segregation distorter (SD) chromosome. J Ultrastruct Res. 1977 Jan;58(1):96–107. [PubMed]
  • Vaury C, Bucheton A, Pelisson A. The beta heterochromatic sequences flanking the I elements are themselves defective transposable elements. Chromosoma. 1989 Sep;98(3):215–224. [PubMed]
  • Wu CI, Lyttle TW, Wu ML, Lin GF. Association between a satellite DNA sequence and the Responder of Segregation Distorter in D. melanogaster. Cell. 1988 Jul 15;54(2):179–189. [PubMed]

Articles from Genetics are provided here courtesy of Genetics Society of America

Formats:

Related citations in PubMed

Cited by other articles in PMC

See all...

Links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...