• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of geneticsGeneticsCurrent IssueInformation for AuthorsEditorial BoardSubscribeSubmit a Manuscript
Genetics. Nov 1992; 132(3): 713–723.
PMCID: PMC1205209

Dynamics of Cytoplasmic Incompatibility and Mtdna Variation in Natural Drosophila Simulans Populations

Abstract

In Drosophila simulans a cytoplasmically transmitted microorganism causes reduced egg hatch when infected males mate with uninfected females. The infection is rapidly spreading northward in California. Data on a specific mtDNA restriction site length polymorphism show that changes in the frequency of mtDNA variants are associated with this spread. All infected flies possess the same mtDNA allele, whereas the uninfected flies are polymorphic. Given that both paternal inheritance of the infection and imperfect maternal transmission have been demonstrated, one might expect instead that both infected and uninfected flies would possess both mtDNA variants. Our data suggest that imperfect female transmission of the infection (and/or the loss of the infection among progeny) is more common in nature than paternal transmission. A simple model of intrapopulation dynamics, with empirically supported parameter values, adequately describes the joint frequencies of the mtDNA variants and incompatibility types.

Full Text

The Full Text of this article is available as a PDF (1.0M).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Asmussen MA, Arnold J, Avise JC. Definition and properties of disequilibrium statistics for associations between nuclear and cytoplasmic genotypes. Genetics. 1987 Apr;115(4):755–768. [PMC free article] [PubMed]
  • Baba-Aïssa F, Solignac M, Dennebouy N, David JR. Mitochondrial DNA variability in Drosophila simulans: quasi absence of polymorphism within each of the three cytoplasmic races. Heredity (Edinb) 1988 Dec;61(Pt 3):419–426. [PubMed]
  • Curtis CF. Population replacement in Culex fatigans by means of cytoplasmic incompatibility. 2. Field cage experiments with overlapping generations. Bull World Health Organ. 1976;53(1):107–119. [PMC free article] [PubMed]
  • Curtis CF. Selfish genes in mosquitoes. Nature. 1992 Jun 11;357(6378):450–450. [PubMed]
  • Fine PE. On the dynamics of symbiote-dependent cytoplasmic incompatibility in culicine mosquitoes. J Invertebr Pathol. 1978 Jan;31(1):10–18. [PubMed]
  • Hoffmann AA, Turelli M. Unidirectional incompatibility in Drosophila simulans: inheritance, geographic variation and fitness effects. Genetics. 1988 Jun;119(2):435–444. [PMC free article] [PubMed]
  • Hoffmann AA, Turelli M, Harshman LG. Factors affecting the distribution of cytoplasmic incompatibility in Drosophila simulans. Genetics. 1990 Dec;126(4):933–948. [PMC free article] [PubMed]
  • Kondo R, Satta Y, Matsuura ET, Ishiwa H, Takahata N, Chigusa SI. Incomplete maternal transmission of mitochondrial DNA in Drosophila. Genetics. 1990 Nov;126(3):657–663. [PMC free article] [PubMed]
  • Nigro L, Prout T. Is there selection on RFLP differences in mitochondrial DNA? Genetics. 1990 Jul;125(3):551–555. [PMC free article] [PubMed]
  • O'Neill SL, Karr TL. Bidirectional incompatibility between conspecific populations of Drosophila simulans. Nature. 1990 Nov 8;348(6297):178–180. [PubMed]
  • O'Neill SL, Giordano R, Colbert AM, Karr TL, Robertson HM. 16S rRNA phylogenetic analysis of the bacterial endosymbionts associated with cytoplasmic incompatibility in insects. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2699–2702. [PMC free article] [PubMed]
  • Rousset F, Vautrin D, Solignac M. Molecular identification of Wolbachia, the agent of cytoplasmic incompatibility in Drosophila simulans, and variability in relation with host mitochondrial types. Proc Biol Sci. 1992 Mar 23;247(1320):163–168. [PubMed]
  • Stevens L. Environmental factors affecting reproductive incompatibility in flour beetles, genus Tribolium. J Invertebr Pathol. 1989 Jan;53(1):78–84. [PubMed]
  • Stevens L, Wade MJ. Cytoplasmically inherited reproductive incompatibility in Tribolium flour beetles: the rate of spread and effect on population size. Genetics. 1990 Feb;124(2):367–372. [PMC free article] [PubMed]
  • Tamura K, Aotsuka T. Rapid isolation method of animal mitochondrial DNA by the alkaline lysis procedure. Biochem Genet. 1988 Dec;26(11-12):815–819. [PubMed]
  • Turelli M, Hoffmann AA. Rapid spread of an inherited incompatibility factor in California Drosophila. Nature. 1991 Oct 3;353(6343):440–442. [PubMed]

Articles from Genetics are provided here courtesy of Genetics Society of America

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...