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Genetics. Jul 1984; 107(3): 355–365.
PMCID: PMC1202328

Coincident Gene Conversion during Mitosis in Saccharomyces

Abstract

During mitosis, gene conversion events at the TRP5 locus on chromosome VII are coupled with conversion events at LEU1 , a locus 18 cM away, 1200 times more frequently than would be expected for two independent acts of recombination. Such coincident conversion events that occur over relatively long distances could be due to several mechanisms. We discuss these possibilities and describe an experiment that indicates that a portion of coincident events is due to extensive heteroduplexes. The phenomenon of coincident gene conversion is discussed in relation to our earlier evidence that spontaneous recombination between homologues occurs prereplicationally in mitosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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