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Genetics. Nov 1983; 105(3): 767–779.
PMCID: PMC1202185

Estimation of the Coancestry Coefficient: Basis for a Short-Term Genetic Distance

Abstract

A distance measure for populations diverging by drift only is based on the coancestry coefficient θ, and three estimators of the distance D = -ln(1 - θ) are constructed for multiallelic, multilocus data. Simulations of a monoecious population mating at random showed that a weighted ratio of single-locus estimators performed better than an unweighted average or a least squares estimator. Jackknifing over loci provided satisfactory variance estimates of distance values. In the drift situation, in which mutation is excluded, the weighted estimator of D appears to be a better measure of distance than others that have appeared in the literature.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Nei M. The theory of genetic distance and evolution of human races. Jinrui Idengaku Zasshi. 1978 Dec;23(4):341–369. [PubMed]
  • Nei M, Roychoudhury AK. Sampling variances of heterozygosity and genetic distance. Genetics. 1974 Feb;76(2):379–390. [PMC free article] [PubMed]

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