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Published online Jul 2, 2005. doi:  10.1186/1471-2180-5-40

Table 1

Detailed analysis of the effects of preincubating cultures of A. awamori with 3,5-DCP, Cr6+ and Zn2+ on [Ca2+]c response to 5 mM external CaCl2

ToxicantFeatures of [Ca2+]C Signatures
ALT50FRL (%) 5 min pre-incubationRT (%) 5 min pre-incubationFRL (%) 30 min pre-incubationRT (%) 30 min pre-incubation

3,5-DCP0.112-111 ± 8.4 (↑)111 ± 8.4 (↑)106 ± 7.6 (-)98 ± 1.3 (-)
(mgl-1)11.2-120 ± 4.8 (↑)125 ± 4.6 (↑)127 ± 29.7 (-)134 ± 31.9 (↑)
112289 ± 17.6 (↑)292 ± 6.6 (↑)416 ± 23.2 (↑)416 ± 16.6 (↑)
Cr6+15-----
(mgl-1)120-----
260-----
Zn2+180-106 ± 9.2(-)127 ± 4.6 (↑)97 ± 6.9(-)92 ± 1.9(↓)
(mgl-1)350-153 ± 13.6(↑)167 ± 14.4(↑)149 ± 11.4(↑)143 ± 10.2(↑)
700164 ± 30.7(↑)179 ± 26.9(↑)245 ± 16.5(↑)261 ± 9.6(↑)
1300169 ± 14.8(↑)182 ± 10.4(↑)169± 12.6(↑)176 ± 16.5(↑)

Note: – no effect compared with untreated control), ↑ increase in parameter, ↓ decrease in parameter, A – amplitude, LT50 – Length of transient, FRL – Final Ca2+ resting level, RT – recovery time. A and LT50 are shown only for 5 min incubation. Results represent mean ± SD. The % values represent the absolute value of the parameter not the relative increase compared with control. N = 6