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Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
Karin Lundberg, Suzanne Nijenhuis, Erik R Vossenaar, Karin Palmblad, Walter J van Venrooij, Lars Klareskog, AJW Zendman, Helena Erlandsson Harris
Arthritis Res Ther. 2005; 7(3): R458–R467. Published online 2005 February 21. doi: 10.1186/ar1697
PMCID:
PMC1174941
Abstract Full Text PDF–876K

Is Cited by the Following 26 Articles in this Archive:

Detection and Quantification of Citrullinated Chemokines
Eva A. V. Moelants, Jo Van Damme, Paul Proost
PLoS One. 2011; 6(12): e28976. Published online 2011 December 16. doi: 10.1371/journal.pone.0028976
PMCID:
PMC3241686
Abstract Full Text PDF–678K
Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis
Hirofumi Shoda, Keishi Fujio, Mihoko Shibuya, Tomohisa Okamura, Shuji Sumitomo, Akiko Okamoto, Tetsuji Sawada, Kazuhiko Yamamoto
Arthritis Res Ther. 2011; 13(6): R191. Published online 2011 November 22. doi: 10.1186/ar3520
PMCID:
PMC3334641
Abstract Full Text PDF–416K Supplementary Material
The development of N-α-(2-carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide (o-F-amidine) and N α-(2-carboxyl)benzoyl-N5-(2-Chloro-1-iminoethyl)-L-ornithine amide (o-Cl-amidine) as second generation Protein Arginine Deiminase (PAD) inhibitors.
Corey P. Causey, Justin E. Jones, Jessica L Slack, Daisuke Kamei, Larry E. Jones, Jr, Venkataraman Subramanian, Bryan Knuckley, Pedram Ebrahimi, Alexander A. Chumanevich, Yuan Luo, Hiroshi Hashimoto, Mamoru Sato, Lorne J. Hofseth, Paul R. Thompson
J Med Chem. Author manuscript; available in PMC 2012 October 13.
Published in final edited form as: J Med Chem. 2011 October 13; 54(19): 6919–6935. Published online 2011 September 16. doi: 10.1021/jm2008985
PMCID:
PMC3196593
Free in PMC on 2012/10/13
Identification of Cit H3 as a Potential Serum Protein Biomarker in a Lethal Model of LPS-induced Shock
Yongqing Li, Baoling Liu, Eugene Y. Fukudome, Jenifer Lu, Wei Chong, Guang Jin, Zhengcai Liu, George C. Velmahos, Marc deMoya, David R. King, Hasan B. Alam
Surgery. Author manuscript; available in PMC 2012 September 1.
Published in final edited form as: Surgery. 2011 September; 150(3): 442–451. doi: 10.1016/j.surg.2011.07.003
PMCID:
PMC3170094
Free in PMC on 2012/09/01
Discovery of Peptidylarginine Deiminase-4 Substrates by Protein Array: Antagonistic Citrullination and Methylation of Human Ribosomal Protein S2
Qin Guo, Mark T. Bedford, Walter Fast
Mol Biosyst. Author manuscript; available in PMC 2012 July 1.
Published in final edited form as: Mol Biosyst. 2011 July; 7(7): 2286–2295. Published online 2011 May 16. doi: 10.1039/c1mb05089c
PMCID:
PMC3251905
Free in PMC on 2012/07/01
The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis
Katleen Van Steendam, Kelly Tilleman, Dieter Deforce
Rheumatology (Oxford) 2011 May; 50(5): 830–837. Published online 2011 January 27. doi: 10.1093/rheumatology/keq419
PMCID:
PMC3077912
Abstract Full Text PDF–76K
Rheumatoid Arthritis: A Role for Immunosenescence?
Tamsin M. Lindstrom, William H. Robinson
J Am Geriatr Soc. Author manuscript; available in PMC 2011 August 1.
Published in final edited form as: J Am Geriatr Soc. 2010 August; 58(8): 1565–1575. Published online 2010 July 19. doi: 10.1111/j.1532-5415.2010.02965.x
PMCID:
PMC3055796
Abstract Full Text PDF–708K
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis
Zoltán Jakus, Edina Simon, Bálint Balázs, Attila Mócsai
Arthritis Rheum. 2010 July; 62(7): 1899–1910. doi: 10.1002/art.27438
PMCID:
PMC2972644
Abstract Full Text PDF–1.3M
Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study
So-Young Bang, Tae-Un Han, Chan-Bum Choi, Yoon-Kyoung Sung, Sang-Cheol Bae, Changwon Kang
Arthritis Res Ther. 2010; 12(3): R115. Published online 2010 June 10. doi: 10.1186/ar3051
PMCID:
PMC2911908
Abstract Full Text PDF–739K Supplementary Material
Carbamylation-Dependent Activation of T Cells: A Novel Mechanism in the Pathogenesis of Autoimmune Arthritis
Piotr Mydel, Zeneng Wang, Mikael Brisslert, Annelie Hellvard, Leif E. Dahlberg, Stanley L. Hazen, Maria Bokarewa
J Immunol. Author manuscript; available in PMC 2010 December 1.
Published in final edited form as: J Immunol. 2010 June 15; 184(12): 6882–6890. Published online 2010 May 19. doi: 10.4049/jimmunol.1000075
PMCID:
PMC2925534
Abstract Full Text PDF–1.4M Supplementary Material
Pre-Clinical Rheumatoid Arthritis: Identification, Evaluation and Future Directions for Investigation
Kevin D. Deane, Jill M. Norris, V. Michael Holers
Rheum Dis Clin North Am. Author manuscript; available in PMC 2011 May 1.
Published in final edited form as: Rheum Dis Clin North Am. 2010 May; 36(2): 213–241. doi: 10.1016/j.rdc.2010.02.001
PMCID:
PMC2879710
Abstract Full Text PDF–415K
The Rheumatoid Arthritis HLA-DRB1 Shared Epitope
Joseph Holoshitz
Curr Opin Rheumatol. Author manuscript; available in PMC 2011 May 1.
Published in final edited form as: Curr Opin Rheumatol. 2010 May; 22(3): 293–298. doi: 10.1097/BOR.0b013e328336ba63
PMCID:
PMC2921962
Abstract Full Text PDF–309K
Smoking and nicotine exposure delay development of collagen-induced arthritis in mice
Sofia S Lindblad, Piotr Mydel, Ing-Marie Jonsson, Robert M Senior, Andrej Tarkowski, Maria Bokarewa
Arthritis Res Ther. 2009; 11(3): R88. Published online 2009 June 11. doi: 10.1186/ar2728
PMCID:
PMC2714144
Abstract Full Text PDF–407K
Mutual Information for Testing Gene-Environment Interaction
Xuesen Wu, Li Jin, Momiao Xiong
PLoS ONE. 2009; 4(2): e4578. Published online 2009 February 24. doi: 10.1371/journal.pone.0004578
PMCID:
PMC2642626
Abstract Full Text PDF–349K Supplementary Material
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system
Abdiwahab A. Musse, Zhen Li, Cameron A. Ackerley, Dorothee Bienzle, Helena Lei, Roberto Poma, George Harauz, Mario A. Moscarello, Fabrizio G. Mastronardi
Dis Model Mech. 2008 Nov-Dec; 1(4-5): 229–240. Published online 2008 November 6. doi: 10.1242/dmm.000729
PMCID:
PMC2590822
Abstract Full Text
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis
Xiaoyan Zhao, Nwora Lance Okeke, Orr Sharpe, Franak M Batliwalla, Annette T Lee, Peggy P Ho, Beren H Tomooka, Peter K Gregersen, William H Robinson
Arthritis Res Ther. 2008; 10(4): R94. Published online 2008 August 18. doi: 10.1186/ar2478
PMCID:
PMC2575608
Abstract Full Text PDF–1.0M
An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4)
Corey P. Causey, Paul R. Thompson
Tetrahedron Lett. Author manuscript; available in PMC 2009 July 7.
Published in final edited form as: Tetrahedron Lett. 2008 July 7; 49(28): 4383–4385. doi: 10.1016/j.tetlet.2008.05.021
PMCID:
PMC2597826
Abstract Full Text PDF–248K Supplementary Material
Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice
Jonathan A. Hill, David A. Bell, William Brintnell, David Yue, Bret Wehrli, Anthony M. Jevnikar, David M. Lee, Wolfgang Hueber, William H. Robinson, Ewa Cairns
J Exp Med. 2008 April 14; 205(4): 967–979. doi: 10.1084/jem.20072051
PMCID:
PMC2292232
Abstract Full Text PDF–3.2M Supplementary Material
Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis
Therese Östberg, Heidi Wähämaa, Karin Palmblad, Norimasa Ito, Pernilla Stridh, Maria Shoshan, Michael T Lotze, Helena Erlandsson Harris, Ulf Andersson
Arthritis Res Ther. 2008; 10(1): R1. Published online 2008 January 7. doi: 10.1186/ar2347
PMCID:
PMC2374449
Abstract Full Text PDF–1.5M
Profiling Protein Arginine Deiminase 4 (PAD4): A novel screen to identify PAD4 inhibitors
Bryan Knuckley, Yuan Luo, Paul R. Thompson
Bioorg Med Chem. Author manuscript; available in PMC 2009 January 15.
Published in final edited form as: Bioorg Med Chem. 2008 January 15; 16(2): 739–745. Published online 2007 October 13. doi: 10.1016/j.bmc.2007.10.021
PMCID:
PMC2267747
Abstract Full Text PDF–1.1M
Protein Arginine Deiminase 4: Evidence for a reverse protonation mechanism
Bryan Knuckley, Monica Bhatia, Paul R. Thompson
Biochemistry. Author manuscript; available in PMC 2008 January 23.
Published in final edited form as: Biochemistry. 2007 June 5; 46(22): 6578–6587. Published online 2007 May 12. doi: 10.1021/bi700095s
PMCID:
PMC2212595
Abstract Full Text PDF–1.3M Supplementary Material
Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis
Henrik Källberg, Leonid Padyukov, Robert M. Plenge, Johan Rönnelid, Peter K. Gregersen, Annette H. M. van der Helm-van Mil, Rene E. M. Toes, Tom W. Huizinga, Lars Klareskog, Lars Alfredsson, Epidemiological Investigation of Rheumatoid Arthritis (EIRA) Study Group
Am J Hum Genet. 2007 May; 80(5): 867–875. Published online 2007 April 2.
PMCID:
PMC1852748
Abstract Full Text PDF–167K
Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization
Yuan Luo, Kyouhei Arita, Monica Bhatia, Bryan Knuckley, Young-Ho Lee, Michael R. Stallcup, Mamoru Sato, Paul R. Thompson
Biochemistry. Author manuscript; available in PMC 2007 March 2.
Published in final edited form as: Biochemistry. 2006 October 3; 45(39): 11727–11736. doi: 10.1021/bi061180d
PMCID:
PMC1808342
Abstract Full Text PDF–865K Supplementary Material
Post-translational modifications of the major linear epitope 169–190aa of Ro60 kDa autoantigen alter the autoantibody binding
A G Terzoglou, J G Routsias, H M Moutsopoulos, A G Tzioufas
Clin Exp Immunol. 2006 October; 146(1): 60–65. doi: 10.1111/j.1365-2249.2006.03192.x
PMCID:
PMC1809728
Abstract Full Text PDF–210K
In the rat, citrullinated autologous fibrinogen is immunogenic but the induced autoimmune response is not arthritogenic
V Duplan, C Foulquier, C Clavel, R Al Badine, G Serre, A Saoudi, M Sebbag
Clin Exp Immunol. 2006 September 1; 145(3): 502–512. doi: 10.1111/j.1365-2249.2006.03168.x
PMCID:
PMC1809699
Abstract Full Text PDF–433K
Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study
Luis M Amezcua-Guerra, Rashidi Springall, Ricardo Marquez-Velasco, Lorena Gómez-García, Angélica Vargas, Rafael Bojalil
Arthritis Res Ther. 2006; 8(5): R144. Published online 2006 August 25. doi: 10.1186/ar2036
PMCID:
PMC1779435
Abstract Full Text PDF–127K
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