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Biochem J. 1982 Aug 1; 205(2): 461–463.
PMCID: PMC1158503

Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts is a feasible source of hydroxy radicals in vivo.

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Selected References

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  • Blake DR, Hall ND, Bacon PA, Dieppe PA, Halliwell B, Gutteridge JM. The importance of iron in rheumatoid disease. Lancet. 1981 Nov 21;2(8256):1142–1144. [PubMed]
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  • Gutteridge JM, Rowley DA, Halliwell B. Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Detection of 'free' iron in biological systems by using bleomycin-dependent degradation of DNA. Biochem J. 1981 Oct 1;199(1):263–265. [PMC free article] [PubMed]
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  • Repine JE, Fox RB, Berger EM. Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical. J Biol Chem. 1981 Jul 25;256(14):7094–7096. [PubMed]
  • Rowley DA, Halliwell B. Superoxide-dependent formation of hydroxyl radicals in the presence of thiol compounds. FEBS Lett. 1982 Feb 8;138(1):33–36. [PubMed]
  • Tangerås A, Flatmark T, Bäckström D, Ehrenberg A. Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state. Biochim Biophys Acta. 1980 Feb 8;589(2):162–175. [PubMed]
  • Winterbourn CC. Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals. Biochem J. 1979 Aug 15;182(2):625–628. [PMC free article] [PubMed]
  • Winterbourn CC. Hydroxyl radical production in body fluids. Roles of metal ions, ascorbate and superoxide. Biochem J. 1981 Jul 15;198(1):125–131. [PMC free article] [PubMed]
  • Wong SF, Halliwell B, Richmond R, Skowroneck WR. The role of superoxide and hydroxyl radicals in the degradation of hyaluronic acid induced by metal ions and by ascorbic acid. J Inorg Biochem. 1981 Apr;14(2):127–134. [PubMed]

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