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Journal List > J Clin Pathol > v.41(4); Apr 1988

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J Clin Pathol. 1988 April; 41(4): 441–443.
PMCID: PMC1141472
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Hepatic tumours induced by anabolic steroids in an athlete.
T M Creagh, A Rubin, and D J Evans
Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital.
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Abstract
A fatal rupture of an hepatic tumour occurred in an athlete who had been taking anabolic steroids for several years as an aid to body building. The case illustrates the hazards of non-therapeutic androgen administration, and emphasises the need for athletes to be made clear of the disturbances to gonadal function, liver structure and function, and the threat to life.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Ishak KG. Hepatic neoplasms associated with contraceptive and anabolic steroids. Recent Results Cancer Res. 1979;66:73–128. [PubMed]
  • Paradinas FJ, Bull TB, Westaby D, Murray-Lyon IM. Hyperplasia and prolapse of hepatocytes into hepatic veins during longterm methyltestosterone therapy: possible relationships of these changes to the developement of peliosis hepatis and liver tumours. Histopathology. 1977 Jul;1(4):225–246. [PubMed]
  • Farrell GC, Joshua DE, Uren RF, Baird PJ, Perkins KW, Kronenberg H. Androgen-induced hepatoma. Lancet. 1975 Feb 22;1(7904):430–432. [PubMed]
  • McCaughan GW, Bilous MJ, Gallagher ND. Long-term survival with tumor regression in androgen-induced liver tumors. Cancer. 1985 Dec 1;56(11):2622–2626. [PubMed]
  • Anthony PP. Letter: hepatoma associated with androgenic steroids. Lancet. 1975 Mar 22;1(7908):685–686. [PubMed]
  • Westaby D, Portmann B, Williams R. Androgen related primary hepatic tumors in non-Fanconi patients. Cancer. 1983 May 15;51(10):1947–1952. [PubMed]
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