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J Clin Pathol. Jan 1988; 41(1): 93–96.
PMCID: PMC1141342

Tuberculous lymphadenitis associated with human immunodeficiency virus (HIV) in Uganda.

Abstract

Sixteen adults presented with lymphadenopathy which was tuberculous on biopsy; they were all seropositive for human immunodeficiency virus (HIV-1), but none had the clinical criteria of the acquired immunodeficiency syndrome (AIDS). The biopsy specimen showed caseating tuberculosis, with scanty or no visible acid fast bacilli in seven cases; the remaining nine had a poor cellular reactivity with numerous bacilli. Antituberculous chemotherapy for two months reduced the lymphadenopathy. Two patients subsequently developed AIDS. Mycobacterial cultures were not performed, but the infection was almost certainly Mycobacterium tuberculosis. The space-time clustering of tuberculous lymphadenitis now seen in Kampala, and the unusual non-reactive histopathology, are typical of the impairment of cellular immunity induced by HIV infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Fauci AS, Masur H, Gelmann EP, Markham PD, Hahn BH, Lane HC. NIH conference. The acquired immunodeficiency syndrome: an update. Ann Intern Med. 1985 Jun;102(6):800–813. [PubMed]
  • Mann J, Snider DE, Jr, Francis H, Quinn TC, Colebunders RL, Piot P, Curran JW, Nzilambi N, Bosenge N, Malonga M, et al. Association between HTLV-III/LAV infection and tuberculosis in Zaire. JAMA. 1986 Jul 18;256(3):346–346. [PubMed]
  • Duncanson FP, Hewlett D, Jr, Maayan S, Estepan H, Perla EN, McLean T, Rodriguez A, Miller SN, Lenox T, Wormser GP. Mycobacterium tuberculosis infection in the acquired immunodeficiency syndrome. A review of 14 patients. Tubercle. 1986 Dec;67(4):295–302. [PubMed]
  • Pitchenik AE, Cole C, Russell BW, Fischl MA, Spira TJ, Snider DE., Jr Tuberculosis, atypical mycobacteriosis, and the acquired immunodeficiency syndrome among Haitian and non-Haitian patients in south Florida. Ann Intern Med. 1984 Nov;101(5):641–645. [PubMed]
  • O'BRIEN JR. Non-reactive tuberculosis. J Clin Pathol. 1954 Aug;7(3):216–225. [PMC free article] [PubMed]
  • Tuberculosis in Kenya: a national sampling survey of drug resistance and other factors. Tubercle. 1968 Jun;49(2):136–169. [PubMed]

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