• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jclinpathJournal of Clinical PathologyVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
J Clin Pathol. May 1987; 40(5): 535–540.
PMCID: PMC1141020

Granulomatous lobular mastitis.

Abstract

The clinical and pathological features of nine cases of granulomatous mastitis were compared with those of 10 cases of duct ectasia/periductal mastitis (DE/PM), all of which were associated with active granulomatous inflammation. Granulomatous mastitis affects a younger age group, and although there is some overlap with DE/PM, it has distinctive pathological features, particularly a lobule centred distribution, for which the term "granulomatous lobular mastitis" is recommended. There is a strong tendency for persistence or recurrence. Our cases of granulomatous mastitis all occurred in parous women, five of them within three years of pregnancy. Awareness of this condition is important, because surgery does not offer the best treatment of recurrent disease, and trials of adequate drug treatment, including corticosteroids, are required.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.9M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Kessler E, Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol. 1972 Dec;58(6):642–646. [PubMed]
  • Fletcher A, Magrath IM, Riddell RH, Talbot IC. Granulomatous mastitis: a report of seven cases. J Clin Pathol. 1982 Sep;35(9):941–945. [PMC free article] [PubMed]
  • Koelmeyer TD, MacCormick DE. Granulomatous mastitis. Aust N Z J Surg. 1976 May;46(2):173–176. [PubMed]
  • Cohen C. Granulomatous mastitis. A review of 5 cases. S Afr Med J. 1977 Jul 2;52(1):14–16. [PubMed]
  • DeHertogh DA, Rossof AH, Harris AA, Economou SG. Prednisone management of granulomatous mastitis. N Engl J Med. 1980 Oct 2;303(14):799–800. [PubMed]
  • Carmalt HL, Ramsey-Stewart G. Granulomatous mastitis. Med J Aust. 1981 Apr 4;1(7):356–359. [PubMed]
  • Rowe PH. Granulomatous mastitis associated with a pituitary prolactinoma. Br J Clin Pract. 1984 Jan;38(1):32–34. [PubMed]
  • Milward TM, Gough MH. Granulomatous lesions in the breast presenting as carcinoma. Surg Gynecol Obstet. 1970 Mar;130(3):478–482. [PubMed]
  • Davies JD, Burton PA. Postpartum lobular granulomatous mastitis. J Clin Pathol. 1983 Mar;36(3):363–363. [PMC free article] [PubMed]
  • Dixon JM, Anderson TJ, Lumsden AB, Elton RA, Roberts MM, Forrest AP. Mammary duct ectasia. Br J Surg. 1983 Oct;70(10):601–603. [PubMed]
  • Bundred NJ, Dixon JM, Lumsden AB, Radford D, Hood J, Miles RS, Chetty U, Forrest AP. Are the lesions of duct ectasia sterile? Br J Surg. 1985 Oct;72(10):844–845. [PubMed]
  • Miles RS, Hood J, Bundred NJ, Jeffrey RJ, Davies GC, Collee JG. The role of Robertson's cooked-meat broth in the bacteriological evaluation of surgical specimens. J Med Microbiol. 1985 Dec;20(3):373–378. [PubMed]
  • Studdy PR, Lapworth R, Bird R. Angiotensin-converting enzyme and its clinical significance--a review. J Clin Pathol. 1983 Aug;36(8):938–947. [PMC free article] [PubMed]
  • Banik S, Bishop PW, Ormerod LP, O'Brien TE. Sarcoidosis of the breast. J Clin Pathol. 1986 Apr;39(4):446–448. [PMC free article] [PubMed]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...