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Biochem J. Jan 15, 1994; 297(Pt 2): 249–260.
PMCID: PMC1137821

The structure and function of proline-rich regions in proteins.

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  • Balasubramanian R, Lakshminarayanan AV, Sabesan MN, Tegoni G, Venkatesan K, Ramachandran GN. Studies on the conformation of amino acids. VI. Conformation of the proline ring as observed in crystal structures of amino acids and peptides. Int J Protein Res. 1971;3(1):25–33. [PubMed]
  • Morris AL, MacArthur MW, Hutchinson EG, Thornton JM. Stereochemical quality of protein structure coordinates. Proteins. 1992 Apr;12(4):345–364. [PubMed]
  • MacArthur MW, Thornton JM. Influence of proline residues on protein conformation. J Mol Biol. 1991 Mar 20;218(2):397–412. [PubMed]
  • Nicholson H, Tronrud DE, Becktel WJ, Matthews BW. Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers. 1992 Nov;32(11):1431–1441. [PubMed]
  • Hurley JH, Mason DA, Matthews BW. Flexible-geometry conformational energy maps for the amino acid residue preceding a proline. Biopolymers. 1992 Nov;32(11):1443–1446. [PubMed]
  • Williams KA, Deber CM. Proline residues in transmembrane helices: structural or dynamic role? Biochemistry. 1991 Sep 17;30(37):8919–8923. [PubMed]
  • Sankararamakrishnan R, Vishveshwara S. Characterization of proline-containing alpha-helix (helix F model of bacteriorhodopsin) by molecular dynamics studies. Proteins. 1993 Jan;15(1):26–41. [PubMed]
  • Richardson JS, Richardson DC. Amino acid preferences for specific locations at the ends of alpha helices. Science. 1988 Jun 17;240(4859):1648–1652. [PubMed]
  • Deber CM, Bovey FA, Carver JP, Blout ER. Nuclear magnetic resonance evidence for cis-peptide bonds in proline oligomers. J Am Chem Soc. 1970 Oct 21;92(21):6191–6198. [PubMed]
  • Helbecque N, Loucheux-Lefebvre MH. Critical chain length for polyproline-II structure formation in H-Gly-(Pro)n-OH. Int J Pept Protein Res. 1982 Jan;19(1):94–101. [PubMed]
  • Okabayashi H, Isemura T, Sakakibara S. Steric structure of L-proline oligopeptides. II. Far-ultraviolet absorption spectra and optical rotations of L-proline oligopeptides. Biopolymers. 1968;6(3):323–330. [PubMed]
  • Dukor RK, Keiderling TA. Reassessment of the random coil conformation: vibrational CD study of proline oligopeptides and related polypeptides. Biopolymers. 1991 Dec;31(14):1747–1761. [PubMed]
  • Dukor RK, Keiderling TA, Gut V. Vibrational circular dichroism spectra of unblocked proline oligomers. Int J Pept Protein Res. 1991 Sep;38(3):198–203. [PubMed]
  • Blundell TL, Pitts JE, Tickle IJ, Wood SP, Wu CW. X-ray analysis (1. 4-A resolution) of avian pancreatic polypeptide: Small globular protein hormone. Proc Natl Acad Sci U S A. 1981 Jul;78(7):4175–4179. [PMC free article] [PubMed]
  • Darbon H, Bernassau JM, Deleuze C, Chenu J, Roussel A, Cambillau C. Solution conformation of human neuropeptide Y by 1H nuclear magnetic resonance and restrained molecular dynamics. Eur J Biochem. 1992 Oct 15;209(2):765–771. [PubMed]
  • Adzhubei AA, Sternberg MJ. Left-handed polyproline II helices commonly occur in globular proteins. J Mol Biol. 1993 Jan 20;229(2):472–493. [PubMed]
  • Grathwohl C, Wüthrich K. The X-Pro peptide bond as an nmr probe for conformational studies of flexible linear peptides. Biopolymers. 1976 Oct;15(10):2025–2041. [PubMed]
  • Lewis PN, Momany FA, Scheraga HA. Chain reversals in proteins. Biochim Biophys Acta. 1973 Apr 20;303(2):211–229. [PubMed]
  • Green JD, Perham RN, Ullrich SJ, Appella E. Conformational studies of the interdomain linker peptides in the dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. J Biol Chem. 1992 Nov 25;267(33):23484–23488. [PubMed]
  • Bhandari DG, Levine BA, Trayer IP, Yeadon ME. 1H-NMR study of mobility and conformational constraints within the proline-rich N-terminal of the LC1 alkali light chain of skeletal myosin. Correlation with similar segments in other protein systems. Eur J Biochem. 1986 Oct 15;160(2):349–356. [PubMed]
  • Frank G, Weeds AG. The amino-acid sequence of the alkali light chains of rabbit skeletal-muscle myosin. Eur J Biochem. 1974 May 15;44(2):317–334. [PubMed]
  • Hejtmancik JF, Thompson MA, Wistow G, Piatigorsky J. cDNA and deduced protein sequence for the beta B1-crystallin polypeptide of the chicken lens. Conservation of the PAPA sequence. J Biol Chem. 1986 Jan 15;261(2):982–987. [PubMed]
  • Berbers GA, Hoekman WA, Bloemendal H, de Jong WW, Kleinschmidt T, Braunitzer G. Proline- and alanine-rich N-terminal extension of the basic bovine beta-crystallin B1 chains. FEBS Lett. 1983 Sep 19;161(2):225–229. [PubMed]
  • Chen R, Schmidmayr W, Krämer C, Chen-Schmeisser U, Henning U. Primary structure of major outer membrane protein II (ompA protein) of Escherichia coli K-12. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4592–4596. [PMC free article] [PubMed]
  • Roditi I, Schwarz H, Pearson TW, Beecroft RP, Liu MK, Richardson JP, Bühring HJ, Pleiss J, Bülow R, Williams RO, et al. Procyclin gene expression and loss of the variant surface glycoprotein during differentiation of Trypanosoma brucei. J Cell Biol. 1989 Feb;108(2):737–746. [PMC free article] [PubMed]
  • Gaisser S, Braun V. The tonB gene of Serratia marcescens: sequence, activity and partial complementation of Escherichia coli tonB mutants. Mol Microbiol. 1991 Nov;5(11):2777–2787. [PubMed]
  • Brewer S, Tolley M, Trayer IP, Barr GC, Dorman CJ, Hannavy K, Higgins CF, Evans JS, Levine BA, Wormald MR. Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli. J Mol Biol. 1990 Dec 20;216(4):883–895. [PubMed]
  • Hedén LO, Frithz E, Lindahl G. Molecular characterization of an IgA receptor from group B streptococci: sequence of the gene, identification of a proline-rich region with unique structure and isolation of N-terminal fragments with IgA-binding capacity. Eur J Immunol. 1991 Jun;21(6):1481–1490. [PubMed]
  • Pancholi V, Fischetti VA. Isolation and characterization of the cell-associated region of group A streptococcal M6 protein. J Bacteriol. 1988 Jun;170(6):2618–2624. [PMC free article] [PubMed]
  • Fahnestock SR, Alexander P, Nagle J, Filpula D. Gene for an immunoglobulin-binding protein from a group G streptococcus. J Bacteriol. 1986 Sep;167(3):870–880. [PMC free article] [PubMed]
  • Li LJ, Dougan G, Novotny P, Charles IG. P.70 pertactin, an outer-membrane protein from Bordetella parapertussis: cloning, nucleotide sequence and surface expression in Escherichia coli. Mol Microbiol. 1991 Feb;5(2):409–417. [PubMed]
  • Takagi T, Suzuki M, Baba T, Minegishi K, Sasaki S. Complete amino acid sequence of amelogenin in developing bovine enamel. Biochem Biophys Res Commun. 1984 Jun 15;121(2):592–597. [PubMed]
  • Abillon E, Bremier L, Cardinaud R. Conformational calculations on the Ala14-Pro27 LC1 segment of rabbit skeletal myosin. Biochim Biophys Acta. 1990 Mar 1;1037(3):394–400. [PubMed]
  • Hannavy K, Barr GC, Dorman CJ, Adamson J, Mazengera LR, Gallagher MP, Evans JS, Levine BA, Trayer IP, Higgins CF. TonB protein of Salmonella typhimurium. A model for signal transduction between membranes. J Mol Biol. 1990 Dec 20;216(4):897–910. [PubMed]
  • Bennick A. Salivary proline-rich proteins. Mol Cell Biochem. 1982 Jun 11;45(2):83–99. [PubMed]
  • Layfield R, Bannister AJ, Pierce EJ, McDonald CJ. cDNA clones for mouse parotid proline-rich proteins. mRNA regulation by isoprenaline and the nucleotide sequence of proline-rich protein cDNA MP5. Eur J Biochem. 1992 Mar 1;204(2):591–597. [PubMed]
  • Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, Duhig T, Peat N, Burchell J, Pemberton L, Lalani EN, Wilson D. Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin. J Biol Chem. 1990 Sep 5;265(25):15286–15293. [PubMed]
  • Eichinger DJ, Arnot DE, Tam JP, Nussenzweig V, Enea V. Circumsporozoite protein of Plasmodium berghei: gene cloning and identification of the immunodominant epitopes. Mol Cell Biol. 1986 Nov;6(11):3965–3972. [PMC free article] [PubMed]
  • Field JM, Tatham AS, Shewry PR. The structure of a high-Mr subunit of durum-wheat (Triticum durum) gluten. Biochem J. 1987 Oct 1;247(1):215–221. [PMC free article] [PubMed]
  • Tatham AS, Drake AF, Shewry PR. A conformational study of a glutamine- and proline-rich cereal seed protein, C hordein. Biochem J. 1985 Mar 1;226(2):557–562. [PMC free article] [PubMed]
  • Noegel AA, Gerisch G, Lottspeich F, Schleicher M. A protein with homology to the C-terminal repeat sequence of Octopus rhodopsin and synaptophysin is a member of a multigene family in Dictyostelium discoideum. FEBS Lett. 1990 Jun 18;266(1-2):118–122. [PubMed]
  • Hall MD, Hoon MA, Ryba NJ, Pottinger JD, Keen JN, Saibil HR, Findlay JB. Molecular cloning and primary structure of squid (Loligo forbesi) rhodopsin, a phospholipase C-directed G-protein-linked receptor. Biochem J. 1991 Feb 15;274(Pt 1):35–40. [PMC free article] [PubMed]
  • Usheva A, Maldonado E, Goldring A, Lu H, Houbavi C, Reinberg D, Aloni Y. Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein. Cell. 1992 May 29;69(5):871–881. [PubMed]
  • McCaffery CA, DeGennaro LJ. Determination and analysis of the primary structure of the nerve terminal specific phosphoprotein, synapsin I. EMBO J. 1986 Dec 1;5(12):3167–3173. [PMC free article] [PubMed]
  • Mehansho H, Butler LG, Carlson DM. Dietary tannins and salivary proline-rich proteins: interactions, induction, and defense mechanisms. Annu Rev Nutr. 1987;7:423–440. [PubMed]
  • Hagerman AE, Butler LG. The specificity of proanthocyanidin-protein interactions. J Biol Chem. 1981 May 10;256(9):4494–4497. [PubMed]
  • Koleske AJ, Buratowski S, Nonet M, Young RA. A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell. 1992 May 29;69(5):883–894. [PubMed]
  • Mermod N, O'Neill EA, Kelly TJ, Tjian R. The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell. 1989 Aug 25;58(4):741–753. [PubMed]
  • Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns GA. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature. 1990 Feb 22;343(6260):774–778. [PubMed]
  • Trimble WS, Cowan DM, Scheller RH. VAMP-1: a synaptic vesicle-associated integral membrane protein. Proc Natl Acad Sci U S A. 1988 Jun;85(12):4538–4542. [PMC free article] [PubMed]
  • van der Bliek AM, Redelmeier TE, Damke H, Tisdale EJ, Meyerowitz EM, Schmid SL. Mutations in human dynamin block an intermediate stage in coated vesicle formation. J Cell Biol. 1993 Aug;122(3):553–563. [PMC free article] [PubMed]
  • Booker GW, Gout I, Downing AK, Driscoll PC, Boyd J, Waterfield MD, Campbell ID. Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase. Cell. 1993 May 21;73(4):813–822. [PubMed]
  • van der Bliek AM, Meyerowitz EM. Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic. Nature. 1991 May 30;351(6325):411–414. [PubMed]
  • Ren R, Mayer BJ, Cicchetti P, Baltimore D. Identification of a ten-amino acid proline-rich SH3 binding site. Science. 1993 Feb 19;259(5098):1157–1161. [PubMed]
  • Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Nature. 1993 May 6;363(6424):83–85. [PubMed]
  • Gigliotti S, Graziani F, De Ponti L, Rafti F, Manzi A, Lavorgna G, Gargiulo G, Malva C. Sex-, tissue-, and stage-specific expression of a vitelline membrane protein gene from region 32 of the second chromosome of Drosophila melanogaster. Dev Genet. 1989;10(1):33–41. [PubMed]
  • Waring GL, Hawley RJ, Schoenfeld T. Multiple proteins are produced from the dec-1 eggshell gene in Drosophila by alternative RNA splicing and proteolytic cleavage events. Dev Biol. 1990 Nov;142(1):1–12. [PubMed]
  • Janusz M, Wieczorek Z, Spiegel K, Kubik A, Szewczuk Z, Siemion I, Lisowski J. Immunoregulatory properties of synthetic peptides, fragments of a proline-rich polypeptide (PRP) from ovine colostrum. Mol Immunol. 1987 Oct;24(10):1029–1031. [PubMed]
  • McCormack T, Vega-Saenz de Miera EC, Rudy B. Molecular cloning of a member of a third class of Shaker-family K+ channel genes in mammals. Proc Natl Acad Sci U S A. 1990 Jul;87(13):5227–5231. [PMC free article] [PubMed]
  • Liu YS, Low TL, Infante A, Putnam FW. Complete covalent structure of a human IgA1 immunoglobulin. Science. 1976 Sep 10;193(4257):1017–1020. [PubMed]
  • Russell GC, Guest JR. Sequence similarities within the family of dihydrolipoamide acyltransferases and discovery of a previously unidentified fungal enzyme. Biochim Biophys Acta. 1991 Jan 29;1076(2):225–232. [PubMed]
  • Mottram JC, North MJ, Barry JD, Coombs GH. A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual C-terminal extension. FEBS Lett. 1989 Dec 4;258(2):211–215. [PubMed]
  • Adham IM, Klemm U, Maier WM, Hoyer-Fender S, Tsaousidou S, Engel W. Molecular cloning of preproacrosin and analysis of its expression pattern in spermatogenesis. Eur J Biochem. 1989 Jul 1;182(3):563–568. [PubMed]
  • Fuchs PG, Iftner T, Weninger J, Pfister H. Epidermodysplasia verruciformis-associated human papillomavirus 8: genomic sequence and comparative analysis. J Virol. 1986 May;58(2):626–634. [PMC free article] [PubMed]
  • Baer R, Bankier AT, Biggin MD, Deininger PL, Farrell PJ, Gibson TJ, Hatfull G, Hudson GS, Satchwell SC, Séguin C, et al. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature. 1984 Jul 19;310(5974):207–211. [PubMed]
  • Guerini D, Klee CB. Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9183–9187. [PMC free article] [PubMed]
  • Sasaki H, Yokoyama E, Kuroiwa A. Specific DNA binding of the two chicken Deformed family homeodomain proteins, Chox-1.4 and Chox-a. Nucleic Acids Res. 1990 Apr 11;18(7):1739–1747. [PMC free article] [PubMed]
  • Sigler PB. Transcriptional activation. Acid blobs and negative noodles. Nature. 1988 May 19;333(6170):210–212. [PubMed]
  • Suzuki M, Sohma H, Yazawa M, Yagi K, Ebashi S. Histone H1 kinase specific to the SPKK motif. J Biochem. 1990 Sep;108(3):356–364. [PubMed]
  • Brown JD, Beggs JD. Roles of PRP8 protein in the assembly of splicing complexes. EMBO J. 1992 Oct;11(10):3721–3729. [PMC free article] [PubMed]
  • De Camilli P, Greengard P. Synapsin I: a synaptic vesicle-associated neuronal phosphoprotein. Biochem Pharmacol. 1986 Dec 15;35(24):4349–4357. [PubMed]
  • Benfenati F, Valtorta F, Rubenstein JL, Gorelick FS, Greengard P, Czernik AJ. Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I. Nature. 1992 Oct 1;359(6394):417–420. [PubMed]
  • Benfenati F, Valtorta F, Greengard P. Computer modeling of synapsin I binding to synaptic vesicles and F-actin: implications for regulation of neurotransmitter release. Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):575–579. [PMC free article] [PubMed]
  • Trimble WS, Scheller RH. Molecular biology of synaptic vesicle-associated proteins. Trends Neurosci. 1988 Jun;11(6):241–242. [PubMed]
  • Bennett MK, Scheller RH. The molecular machinery for secretion is conserved from yeast to neurons. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2559–2563. [PMC free article] [PubMed]
  • Schlessinger J. How receptor tyrosine kinases activate Ras. Trends Biochem Sci. 1993 Aug;18(8):273–275. [PubMed]
  • Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature. 1993 May 6;363(6424):85–88. [PubMed]
  • Buday L, Downward J. Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell. 1993 May 7;73(3):611–620. [PubMed]
  • Cicchetti P, Mayer BJ, Thiel G, Baltimore D. Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science. 1992 Aug 7;257(5071):803–806. [PubMed]
  • Panayotou G, Waterfield MD. Phosphatidyl-inositol 3-kinase: a key enzyme in diverse signalling processes. Trends Cell Biol. 1992 Dec;2(12):358–360. [PubMed]
  • Collins CA. Dynamin: a novel microtubule-associated GTPase. Trends Cell Biol. 1991 Aug;1(2-3):57–60. [PubMed]
  • Meluh PB, Rose MD. KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell. 1990 Mar 23;60(6):1029–1041. [PubMed]
  • Yu H, Rosen MK, Shin TB, Seidel-Dugan C, Brugge JS, Schreiber SL. Solution structure of the SH3 domain of Src and identification of its ligand-binding site. Science. 1992 Dec 4;258(5088):1665–1668. [PubMed]
  • Musacchio A, Noble M, Pauptit R, Wierenga R, Saraste M. Crystal structure of a Src-homology 3 (SH3) domain. Nature. 1992 Oct 29;359(6398):851–855. [PubMed]
  • Whitney RM, Brunner JR, Ebner KE, Farrell HM, Jr, Josephson RV, Morr CV, Swaisgood HE. Nomemclature of the proteins of cow's milk: fourth revision. J Dairy Sci. 1976 May;59(5):795–815. [PubMed]
  • Farrell HM., Jr Models for casein micelle formation. J Dairy Sci. 1973 Sep;56(9):1195–1206. [PubMed]
  • Rogers S, Wells R, Rechsteiner M. Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science. 1986 Oct 17;234(4774):364–368. [PubMed]
  • Chevaillier P. Pest sequences in nuclear proteins. Int J Biochem. 1993 Apr;25(4):479–482. [PubMed]
  • Radford SE, Laue ED, Perham RN, Martin SR, Appella E. Conformational flexibility and folding of synthetic peptides representing an interdomain segment of polypeptide chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. J Biol Chem. 1989 Jan 15;264(2):767–775. [PubMed]
  • Machado RS, Guest JR, Williamson MP. Mobility in pyruvate dehydrogenase complexes with multiple lipoyl domains. FEBS Lett. 1993 Jun 1;323(3):243–246. [PubMed]
  • Turner SL, Russell GC, Williamson MP, Guest JR. Restructuring an interdomain linker in the dihydrolipoamide acetyltransferase component of the pyruvate dehydrogenase complex of Escherichia coli. Protein Eng. 1993 Jan;6(1):101–108. [PubMed]
  • Eyre DR. Collagen: molecular diversity in the body's protein scaffold. Science. 1980 Mar 21;207(4437):1315–1322. [PubMed]
  • Reid KB. Amino acid sequence of the N-terminal forty-two amino acid residues of the C chain of subcomponent C1q of the first component of human complement. Biochem J. 1977 Feb 1;161(2):247–251. [PMC free article] [PubMed]
  • Chen J, Varner JE. An extracellular matrix protein in plants: characterization of a genomic clone for carrot extensin. EMBO J. 1985 Sep;4(9):2145–2151. [PMC free article] [PubMed]
  • Li XB, Kieliszewski M, Lamport DT. A chenopod extensin lacks repetitive tetrahydroxyproline blocks. Plant Physiol. 1990 Feb;92(2):327–333. [PMC free article] [PubMed]
  • Raz R, Crétin C, Puigdomènech P, Martínez-Izquierdo JA. The sequence of a hydroxyproline-rich glycoprotein gene from Sorghum vulgare. Plant Mol Biol. 1991 Feb;16(2):365–367. [PubMed]
  • Mann K, Schäfer W, Thoenes U, Messerschmidt A, Mehrabian Z, Nalbandyan R. The amino acid sequence of a type I copper protein with an unusual serine- and hydroxyproline-rich C-terminal domain isolated from cucumber peelings. FEBS Lett. 1992 Dec 21;314(3):220–223. [PubMed]
  • Ertl H, Mengele R, Wenzl S, Engel J, Sumper M. The extracellular matrix of Volvox carteri: molecular structure of the cellular compartment. J Cell Biol. 1989 Dec;109(6 Pt 2):3493–3501. [PMC free article] [PubMed]
  • Esquerré-Tugayé MT. Cell Surfaces in Plant-Microorganism Interactions: I. A Structural Investigation of Cell Wall Hydroxyproline-rich Glycoproteins Which Accumulate in Fungus-infected Plants. Plant Physiol. 1979 Aug;64(2):314–319. [PMC free article] [PubMed]
  • McNeil M, Darvill AG, Fry SC, Albersheim P. Structure and function of the primary cell walls of plants. Annu Rev Biochem. 1984;53:625–663. [PubMed]
  • Williamson G, Belshaw NJ, Williamson MP. O-glycosylation in Aspergillus glucoamylase. Conformation and role in binding. Biochem J. 1992 Mar 1;282(Pt 2):423–428. [PMC free article] [PubMed]
  • Gilkes NR, Henrissat B, Kilburn DG, Miller RC, Jr, Warren RA. Domains in microbial beta-1, 4-glycanases: sequence conservation, function, and enzyme families. Microbiol Rev. 1991 Jun;55(2):303–315. [PMC free article] [PubMed]
  • Jentoft N. Why are proteins O-glycosylated? Trends Biochem Sci. 1990 Aug;15(8):291–294. [PubMed]
  • Page MI, Jencks WP. Entropic contributions to rate accelerations in enzymic and intramolecular reactions and the chelate effect. Proc Natl Acad Sci U S A. 1971 Aug;68(8):1678–1683. [PMC free article] [PubMed]
  • Williams DH, Searle MS, Mackay JP, Gerhard U, Maplestone RA. Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics. Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1172–1178. [PMC free article] [PubMed]
  • Cerundolo V, Elliott T, Elvin J, Bastin J, Rammensee HG, Townsend A. The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules. Eur J Immunol. 1991 Sep;21(9):2069–2075. [PubMed]
  • Baron M, Norman DG, Campbell ID. Protein modules. Trends Biochem Sci. 1991 Jan;16(1):13–17. [PubMed]
  • Corden JL. Tails of RNA polymerase II. Trends Biochem Sci. 1990 Oct;15(10):383–387. [PubMed]
  • Veis A, Nawrot CF. Basicity differences among peptide bonds. J Am Chem Soc. 1970 Jul 1;92(13):3910–3914. [PubMed]
  • Laurent BC, Treitel MA, Carlson M. The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes. Mol Cell Biol. 1990 Nov;10(11):5616–5625. [PMC free article] [PubMed]
  • Feigl G, Gram M, Pongs O. A member of the steroid hormone receptor gene family is expressed in the 20-OH-ecdysone inducible puff 75B in Drosophila melanogaster. Nucleic Acids Res. 1989 Sep 25;17(18):7167–7178. [PMC free article] [PubMed]
  • Wootton JC, Drummond MH. The Q-linker: a class of interdomain sequences found in bacterial multidomain regulatory proteins. Protein Eng. 1989 May;2(7):535–543. [PubMed]

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