Photograph of bladder biopsy (HP00/4013): A 56-year male with T-6 paraplegia has been managing the bladder by long-term indwelling urethral catheter. Histology shows moderate to severe superficial, acute and chronic inflammation without ulceration. Polymorphs extend into the overlying urothelium. A lymphoid follicle with germinal centre is included in the mucosa. Approximately one-third of the surface epithelium shows non-keratinising squamous metaplasia.