• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jepicomhInstructions for authorsCurrent TOCJournal of Epidemiology and Community Health
J Epidemiol Community Health. Aug 1992; 46(4): 437–442.
PMCID: PMC1059616

Pulmonary function development in children with past history of asthma.

Abstract

STUDY OBJECTIVE--The aim was to examine whether or not the children with a past history of asthma but free from asthmatic attacks for several years show a different growth pattern in pulmonary function from control children. DESIGN--A community based cohort was surveyed three times during a four year follow up period. SETTING--Kashima district in Ibaraki prefecture, Japan. PARTICIPANTS--In 1980, 441 primary school children between 113 and 124 months of age were enrolled as an initial cohort; 325 of these provided reliable results in each of the three surveys. MAIN RESULTS--A level and a slope of FVC, FEV1, Vmax50, and Vmax25 were calculated for each child, based on a general linear model analysis. Past histories of each child were determined from a standardised questionnaire. The children with a history of doctor diagnosed asthma showed a lower Vmax50 level (p < 0.005) and a lower level and slope of Vmax25 (p < 0.005, p < 0.01) than control children, even when only those who did not suffer from wheezing attacks during the follow up period were considered. CONCLUSIONS--Indices of peripheral airways function in children with an asthmatic history were reduced even if they had been in remission for several years. The difference in pulmonary function in comparison to control children might become greater at the time of the adolescent growth spurt.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Kelly WJ, Hudson I, Raven J, Phelan PD, Pain MC, Olinsky A. Childhood asthma and adult lung function. Am Rev Respir Dis. 1988 Jul;138(1):26–30. [PubMed]
  • Isawa T, Teshima T, Hirano T, Shiraishi K, Matsuda T, Konno K. Regulation of regional perfusion distribution in the lungs: effect of regional oxygen concentration. Am Rev Respir Dis. 1978 Jul;118(1):55–63. [PubMed]
  • Davis GS, Brody AR, Craighead JE. Analysis of airspace and interstitial mononuclear cell populations in human diffuse interstitial lung disease. Am Rev Respir Dis. 1978 Jul;118(1):7–15. [PubMed]
  • Berkey CS, Ware JH, Dockery DW, Ferris BG, Jr, Speizer FE. Indoor air pollution and pulmonary function growth in preadolescent children. Am J Epidemiol. 1986 Feb;123(2):250–260. [PubMed]
  • Kerrebijn KF, Fioole AC, van Bentveld RD. Lung function in asthmatic children after year or more without symptoms or treatment. Br Med J. 1978 Apr 8;1(6117):886–888. [PMC free article] [PubMed]
  • Woolcock AJ, Leeder SR, Peat JK, Blackburn CR. The influence of lower respiratory illness in infancy and childhood and subsequent cigarette smoking on lung function in Sydney schoolchildren. Am Rev Respir Dis. 1979 Jul;120(1):5–14. [PubMed]
  • Martin AJ, Landau LI, Phelan PD. Lung function in young adults who had asthma in childhood. Am Rev Respir Dis. 1980 Oct;122(4):609–616. [PubMed]
  • Yarnell JW, St Leger AS. Respiratory infections and their influence on lung function in children: a multiple regression analysis. Thorax. 1981 Nov;36(11):847–851. [PMC free article] [PubMed]
  • Martinez FD, Morgan WJ, Wright AL, Holberg CJ, Taussig LM. Diminished lung function as a predisposing factor for wheezing respiratory illness in infants. N Engl J Med. 1988 Oct 27;319(17):1112–1117. [PubMed]
  • Park SS. Effect of effort versus volume on forced expiratory flow measurement. Am Rev Respir Dis. 1988 Oct;138(4):1002–1005. [PubMed]
  • Tager IB, Segal MR, Munoz A, Weiss ST, Speizer FE. The effect of maternal cigarette smoking on the pulmonary function of children and adolescents. Analyses of data from two populations. Am Rev Respir Dis. 1987 Dec;136(6):1366–1370. [PubMed]
  • Anderson HR, Bland JM, Patel S, Peckham C. The natural history of asthma in childhood. J Epidemiol Community Health. 1986 Jun;40(2):121–129. [PMC free article] [PubMed]

Articles from Journal of Epidemiology and Community Health are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...