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J Med Genet. Apr 1986; 23(2): 178–180.
PMCID: PMC1049578

Multifocal meningiomas in a patient with a constitutional ring chromosome 22.

Abstract

We report a patient with a constitutional ring chromosome 22, in whom multifocal meningiomas were confirmed at necropsy, and discuss the relationship between the constitutional chromosome change and tumourigenesis of meningiomas in this patient.

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Selected References

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  • Stoll C, Roth MP. Segregation of a 22 ring chromosome in three generations. Hum Genet. 1983;63(3):294–296. [PubMed]
  • Zankl H, Zang KD. Cytological and cytogenetical studies on brain tumors. 4. Identification of the missing G chromosome in human meningiomas as no. 22 by fluorescence technique. Humangenetik. 1972;14(2):167–169. [PubMed]
  • Kondo I, Hamaguchi H, Nakajima S, Haneda T. A cytogenetic survey of 449 patients in a Japanese institution for the mentally retarded. Clin Genet. 1980;17(3):177–182. [PubMed]
  • Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, Gallie BL, Murphree AL, Strong LC, White RL. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature. 305(5937):779–784. [PubMed]
  • Swan DC, McBride OW, Robbins KC, Keithley DA, Reddy EP, Aaronson SA. Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells. Proc Natl Acad Sci U S A. 1982 Aug;79(15):4691–4695. [PMC free article] [PubMed]

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