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Logo of brjopthalBritish Journal of OphthalmologyCurrent TOCInstructions for authors
Br J Ophthalmol. Apr 1977; 61(4): 260–262.
PMCID: PMC1042935

Intraocular gentamicin as intraoperative prophylaxis in South India eye camps.

Abstract

The incidence of bacterial endophthalmitis has been 3-6% after cataract extraction in the eye camps of South India from 1961-75. During this time 50 791 cases were operated using systemic and topical chloramphenicol prophylaxis. This study evaluated the prophylactic intracameral injection of 50 microng of gentamicin in eye camp cataract extractions. Only 6 of 1626 patients treated with intracameral gentamicin at operation developed bacterial endophthalmitis, an incidence of 0-37%.

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Selected References

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  • ALLEN HF, MANGIARACINE AB. BACTERIAL ENDOPHTHALMITIS AFTER CATARACT EXTRACTION. A STUDY OF 22 INFECTIONS IN 20,000 OPERATIONS. Arch Ophthalmol. 1964 Oct;72:454–462. [PubMed]
  • May DR, Ericson ES, Peyman GA, Axelrod AJ. Intraocular injection of gentamicin. Single injection therapy of experimental bacterial endophthalmitis. Arch Ophthalmol. 1974 Jun;91(6):487–489. [PubMed]
  • Peyman GA, May DR, Ericson ES, Apple D. Intraocular injection of gentamicin. Toxic effects of clearance. Arch Ophthalmol. 1974 Jul;92(1):42–47. [PubMed]

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