• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of brjopthalBritish Journal of OphthalmologyCurrent TOCInstructions for authors
Br J Ophthalmol. Aug 1982; 66(8): 500–505.
PMCID: PMC1039835

Refractive change in hyperglycaemia: hyperopia, not myopia.

Abstract

Sudden changes in refraction are well recognised feature of hyperglycaemia. A tendency towards myopia has always been associated with elevations in blood glucose. Twelve diabetic patients were found to have experienced such refractive changes. Review of their records demonstrates that hyperglycaemia produces hyperopia. A theoretical mechanism for this phenomenon is discussed.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1013K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Duke-Elder WS. CHANGES IN REFRACTION IN DIABETES MELLITUS. Br J Ophthalmol. 1925 Apr;9(4):167–187. [PMC free article] [PubMed]
  • ROBERTS W. Rapid lens changes in diabetes mellitus. Am J Ophthalmol. 1950 Aug;33(8):1283–1285. [PubMed]
  • ROSEN M. Diabetes mellitus with relative hyperopia; a case report. Am J Ophthalmol. 1956 Apr;41(4):680–681. [PubMed]
  • Planten JT. Physiologic optic approach of lens and cataract. Ophthalmologica. 1975;171(4-5):249–253. [PubMed]
  • Keller JT. A mechanism for refractive changes in diabetes. Am J Optom Arch Am Acad Optom. 1973 Feb;50(2):108–111. [PubMed]
  • Planten JT, Kooijman AC, de Vries B, Woldringh JJ. Pathological-optic approach of cataract and lens. Ophthalmologica. 1978;176(6):331–334. [PubMed]
  • VAN HAYNINGEN R. The sorbital pathway in the lens. Exp Eye Res. 1962 Jun;1:396–404. [PubMed]
  • PIRIE A, VANHEYNINGEN R. THE EFFECT OF DIABETES ON THE CONTENT OF SORBITOL, GLUCOSE, FRUCTOSE AND INOSITOL IN THE HUMAN LENS. Exp Eye Res. 1964 Jun;3:124–131. [PubMed]
  • KUCK J., Jr The formation of fructose in the ocular lens. Arch Ophthalmol. 1961 Jun;65:840–846. [PubMed]
  • KINOSHITA JH, MEROLA LO, SATOH K, DIKMAK E. Osmotic changes caused by the accumulation of dulcitol in the lenses of rats fed with galactose. Nature. 1962 Jun 16;194:1085–1087. [PubMed]
  • KINOSHITA JH, MEROLA LO. HYDRATION OF THE LENS DURING THE DEVELOPMENT OF GALACTOSE CATARACT. Invest Ophthalmol. 1964 Dec;3:577–584. [PubMed]
  • Chylack LT, Jr, Kinoshita JH. A biochemical evaluation of a cataract induced in a high-glucose medium. Invest Ophthalmol. 1969 Aug;8(4):401–412. [PubMed]
  • Varma SD, El-Aguizy HK, Richards RD. Refractive change in alloxan diabetic rabbits. Control by flavonoids I. Acta Ophthalmol (Copenh) 1980 Oct;58(5):748–759. [PubMed]
  • PATTERSON JW. A REVIEW OF GLUCOSE TRANSPORT IN THE LENS. Invest Ophthalmol. 1965 Aug;4:667–679. [PubMed]
  • Varma SD, Schocket SS, Richards RD. Implications of aldose reductase in cataracts in human diabetes. Invest Ophthalmol Vis Sci. 1979 Mar;18(3):237–241. [PubMed]
  • Jedziniak JA, Chylack LT, Jr, Cheng HM, Gillis MK, Kalustian AA, Tung WH. The sorbitol pathway in the human lens: aldose reductase and polyol dehydrogenase. Invest Ophthalmol Vis Sci. 1981 Mar;20(3):314–326. [PubMed]
  • HUGGERT A. The appearance of the crystalline lens during different stages of transitory changes of refraction. II. Acta Ophthalmol (Copenh) 1954;32(4):375–389. [PubMed]
  • Planten JT. Changes of refraction in the adult eye due to changing refractive indices of the layers of the lens. Ophthalmologica. 1981;183(2):86–90. [PubMed]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • Compound
    Compound
    PubChem Compound links
  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles
  • Substance
    Substance
    PubChem Substance links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...